PROSTOLOR protargol
PROSTOLOR Protargol: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Drug interactions
- 11. Analogs
- 12. Terms and conditions of storage
- 13. Terms of dispensing from pharmacies
- 14. Reviews
- 15. Price in pharmacies
Latin name: Prostolor protargol
ATX code: R01AX10, D08AL
Active ingredient: Silver proteinate
Producer: Obninsk Chemical-Pharmaceutical Company, CJSC (Russia)
Description and photo update: 2019-30-11
PROSTOLOR protargol is an antiseptic drug.
Release form and composition
Dosage form - tablets for preparation of a solution for topical use: flat-cylindrical, round, yellow-brown or brown, with a line on one side and a chamfer on both sides; non-uniformity of staining is possible [in a cardboard box 1 blister containing 1 tablet, 1 polyethylene ampoule with 10 ml of solvent (water for injection), 1 dark glass bottle with a pipette cap and instructions for use of PROSTOLOR Protargol].
Composition of 1 tablet:
- active substance: protargol (silver proteinate) - 200 mg;
- auxiliary component: povidone K-17 - 20 mg.
Pharmacological properties
Pharmacodynamics
When entering the body, silver proteinate dissociates to form silver ions, which have anti-inflammatory, antiseptic and astringent properties. By disrupting the replication of deoxyribonucleic acid (DNA) of bacteria, the bacteriostatic effect of silver ions is manifested.
The main mechanism of action of the drug is that silver ions, falling on the damaged mucous membrane, precipitate proteins and form a protective film that contributes to the narrowing of blood vessels (this leads to a decrease in edema) and a decrease in the sensitivity of nerve endings, which in turn leads to inhibition inflammatory reactions.
Silver ions inhibit the growth of various bacteria. PROSTOLOR protargol is active against gram-positive and gram-negative microorganisms, such as:
- wax bacillus;
- candida albicans;
- colibacillus;
- Pseudomonas aeruginosa;
- Staphylococcus aureus;
- aspergillus black;
- salmonella enteric.
Pharmacokinetics
When applied topically, PROSTOLOR Protargol is practically not absorbed. Its content in plasma is extremely low, systemic side effects and cases of silver intoxication in clinical practice have not been identified.
Indications for use
PROSTOLOR Protargol is prescribed for the symptomatic treatment of sinusitis and acute nasopharyngitis (rhinitis).
Contraindications
- atrophic rhinitis;
- pregnancy;
- period of breastfeeding;
- individual intolerance to the components of the drug.
PROSTOLOR protargol, instructions for use: method and dosage
The solution prepared from the tablet is applied topically. To obtain a 2% solution, 1 tablet is dissolved in 10 ml of water for injection (solvent included in the kit). The finished solution can be stored in a refrigerator at a temperature of 2–8 ° С for a 30-day period (no more).
The drug should be shaken immediately before use.
PROSTOLOR Protargol for children under 6 years of age is prescribed 1-2 drops 2-3 times a day in each nostril. PROSTOLOR protargol children over 6 years old and adults should be used 3-5 drops 2-3 times a day in each nostril.
Side effects
Possible adverse reactions (> 10% - very common;> 1% and 0.1% and 0.01% and <0.1% - rarely; <0.01%, including isolated messages - very rare):
- immune system: rarely - urticaria, itchy skin (allergic reactions); very rarely - atopic dermatitis, Quincke's edema, anaphylactic shock;
- general disorders and disorders at the injection site: rarely - a feeling of numbness and burning of the nasal mucosa, irritation;
- others: rarely - redness of the eyes, dry mouth.
In cases of development of side effects, it is recommended to cancel the use of the drug and seek medical advice.
Overdose
Overdose cases of PROSTOLOR Protargol have not been registered.
special instructions
It is important to carefully read the instructions for use and consult a doctor before starting drug therapy.
The drug should be used individually, by one patient. You should not transfer the drug to other persons, even if there are similar manifestations of pathology, since its use may harm their health.
Before instilling the solution, the nasal passages should be cleaned.
It is important not to exceed the recommended doses of PROSTOLOR protargol, especially in children and elderly patients.
The drug should not be used for more than 7 days, unless a different duration of therapy is recommended by the doctor. In cases where after this period the manifestations of the disease persist, it is necessary to consult a doctor.
It should be borne in mind that the use of a solution can lead to staining of the discharge from the nose in blue or gray.
Influence on the ability to drive vehicles and complex mechanisms
The use of the drug on a person's ability to drive vehicles and work with complex mechanisms has no effect.
Application during pregnancy and lactation
PROSTOLOR Protargol is not prescribed during pregnancy / lactation. If necessary, its use during lactation, breastfeeding is stopped.
Drug interactions
There are no data on the interaction of protargol with other drugs.
Analogs
Protargol PROSTOLOR analogs are Sialor, Protargol-ENT, Protargol.
Terms and conditions of storage
Store in a place protected from light and moisture at temperatures up to 30 ° C. Keep out of the reach of children.
Shelf life is 2 years.
The shelf life of the finished solution should not exceed 30 days.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about PROSTOLOR Protargol
According to reviews, PROSTOLOR Protargol is a safe, effective and fast-acting drug used in the treatment of rhinitis.
Price for PROSTOLOR Protargol in pharmacies
The approximate price of PROSTOLOR Protargol (1 tablet and 10 ml of solvent in the package) is 130 rubles.
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
