Pancreatin-LekT

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Pancreatin-LekT: instructions for use and reviews

1. Release form and composition
2. Pharmacological properties
3. Indications for use
4. Contraindications
5. Method of application and dosage
6. Side effects
7. Overdose
8. Special instructions
9. Application during pregnancy and lactation
10. Use in childhood
11. Drug interactions
12. Analogs
13. Terms and conditions of storage
14. Terms of dispensing from pharmacies
15. Reviews
16. Price in pharmacies

Latin name: Pancreatin-LekT

ATX code: A09AA02

Active ingredient: Pancreatin (Pancreatin)

Producer: Tyumen Chemical-Pharmaceutical Plant (Russia)

Description and photo update: 2018-24-10

Prices in pharmacies: from 36 rubles.

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Pancreatin-LekT is an enzymatic digestive agent.

Release form and composition

Dosage form - enteric-coated tablets: biconvex, pink or dark pink, with a specific odor, without risks; the cross section shows two layers. Packing: blisters - 10, 15 and 20 pcs., In a cardboard box 3, 4 or 6 packages; polymer or orange glass jars - 60 pcs., 1 can in a cardboard box.

Active ingredient: pancreatin, in 1 tablet - 90 mg:

lipolytic activity - not less than 3500 FIP units;
amylolytic activity - not less than 3500 FIP units;
proteolytic activity - not less than 200 FIP units.

Additional components: polysorbate (tween-80), copolymer of methacrylic acid with ethyl acrylate, macrogol (polyethylene glycol 6000), titanium dioxide (titanium dioxide pigment grade A), lactose (lactopress), microcrystalline cellulose, lactose monohydrate (milk sugar), talc, calcium stearate, povidone (low molecular weight polyvinylpyrrolidone), azorubin dye (acid red 2C).

Pharmacological properties

Pharmacodynamics

The active component of Pancreatin-LekT is pancreatin - a substance that compensates for the insufficiency of the exocrine function of the pancreas, providing lipolytic, amylolytic and proteolytic effects.

The enzymes included in the preparation (alpha-amylase, chymotrypsin, trypsin, lipase) promote the breakdown of fats to fatty acids and glycerol, proteins to amino acids, starch to monosaccharides and dextrins.

Trypsin suppresses the stimulated secretion of the pancreas, due to which it has an analgesic effect.

Pancreatin normalizes digestion processes, improves the functional state of the digestive system.

As part of the Pancreatin-LekT preparation, enzymes are protected by a membrane from the action of gastric juice, therefore they are released in the alkaline medium of the small intestine.

The maximum enzymatic activity after taking the drug inside is noted after 30-45 minutes.

Indications for use

violation of food assimilation (conditions after resection of the small intestine or stomach);
inaccuracies in nutrition (irregular eating, eating a large amount of food or fatty foods), prolonged immobilization or a sedentary lifestyle, impaired chewing function - to improve food digestion in people with normal gastrointestinal tract function;
exocrine pancreatic insufficiency (for replacement therapy): flatulence, dyspepsia, diarrhea of non-infectious origin, pancreatectomy, cystic fibrosis, chronic pancreatitis, Remheld syndrome (gastrocardial syndrome), condition after irradiation;
preparing the patient for an ultrasound or X-ray examination of the abdominal organs.

Contraindications

children under 3 years old;
exacerbation of chronic pancreatitis;
acute pancreatitis;
increased sensitivity to the drug.

Instructions for the use of Pancreatin-LekT: method and dosage

Pancreatin-LekT should be taken orally, during or immediately after a meal, swallowing the tablets whole.

Adults are prescribed 1-3 tablets 3-4 times a day.

The attending physician selects the dose for children.

The duration of therapy is individual, it can range from several days (if there are disturbances in the digestive processes due to inaccuracies in nutrition) to several months and even years (during replacement therapy).

Side effects

Pancreatin-LECT may cause allergic reactions. There are isolated cases of a feeling of discomfort in the stomach, constipation, diarrhea, nausea, however, the causal relationship of their development with the action of the drug has not been reliably established, since these phenomena can also be signs of exocrine pancreatic insufficiency.

With prolonged use of the drug in high doses, there is a possibility of an increase in the level of uric acid in the blood plasma and the development of hyperuricosuria. In children, when taking high doses of pancreatin, irritation of the oral mucosa and perianal irritation may occur, in patients with cystic fibrosis - strictures in the ascending colon and ileocecal region.

Overdose

In case of an overdose of pancreatin, hyperuricemia / hyperuricosuria is possible, in children - constipation. In this case, the drug is canceled and symptomatic therapy is performed.

special instructions

If long-term treatment is necessary, it is worth taking iron supplements at the same time.

Patients with cystic fibrosis are not recommended to take Pancreatin-LekT in high doses because of the risk of developing fibrous colonopathy (strictures). The dose must be calculated in such a way that it is adequate for the amount of enzymes required for fat absorption. In this case, the quality and quantity of food consumed must be taken into account.

Influence on the ability to drive vehicles and complex mechanisms

Pancreatin-LekT has no effect on the ability to concentrate and the speed of psychomotor reactions.

Application during pregnancy and lactation

The experience of using pancreatin during pregnancy is not enough to assess the extent of its effect. In the course of experimental studies, it was found that pancreatin does not have teratogenic properties. In this regard, the appointment of Pancreatin-LekT is possible if the intended benefit outweighs the potential risks.

Pediatric use

According to the instructions, Pancreatin-LekT can be used to treat children over 3 years old. It should be borne in mind that with a high activity of lipase contained in pancreatin, children have an increased risk of constipation.

Drug interactions

The activity of pancreatin can be reduced by antacids containing magnesium hydroxide and / or calcium carbonate.

Pancreatin can reduce the absorption of iron preparations.

Analogs

The analogues of Pancreatin-LekT are: Mezim 20,000, Creon 10,000, Creon 25,000, Creon 40,000, Panzim forte, Penzital, Hermital, Mezim forte, Mezim forte 10,000, Gastenorm forte 10,000, Pancreatin forte, PanziKam, Micrasim, Pancreatin, Pangrol 25 000, Enzistal-P, Gastenorm forte, Pancreasim.

Terms and conditions of storage

Shelf life - no more than 2 years from the date of production, subject to the recommended storage regime: dry, protected from light, place inaccessible to children, temperature - up to 20 ° C.

Terms of dispensing from pharmacies

Available without a prescription.

Reviews about Pancreatin-LekT

Reviews about Pancreatin-LekT are positive: the drug helps with impaired absorption of food and errors in nutrition, effectively eliminates heaviness and pain in the stomach, improves digestion. An additional advantage of this tool is its low price.

Price for Pancreatin-Lect in pharmacies

The price for Pancreatin-LekT is 36–47 rubles. per pack of 60 tablets.

Pancreatin-LekT: prices in online pharmacies

Drug name

Price

Pharmacy

Pancreatin-LekT enteric-coated tablets 60 pcs.

RUB 36

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Pancreatin-LekT enteric-coated tablets 60 pcs.

RUB 39

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Pancreatin-LekT tablets p.o. enteric solution. 90mg 60 pcs.

RUB 53

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Pancreatin-LekT enteric-coated tablets 90 pcs.

RUB 65

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Maria Kulkes Medical journalist About the author

Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!