Panadol extra
Panadol extra: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. In case of impaired renal function
- 12. For violations of liver function
- 13. Drug interactions
- 14. Analogs
- 15. Terms and conditions of storage
- 16. Terms of dispensing from pharmacies
- 17. Reviews
- 18. Price in pharmacies
Latin name: Panadol extra
ATX code: N02BE71
Active ingredient: paracetamol (Paracetamol) + caffeine (Caffeine)
Manufacturer: Famar S. A. (Famar SA) (Greece); GlaxoSmithKline Dungarvan, Ltd (Ireland)
Description and photo update: 2019-31-10
Panadol extra is a combined analgesic drug with antipyretic effect.
Release form and composition
Dosage forms:
- coated tablets (12 pcs. in blisters, in a cardboard box 1 blister);
- soluble tablets (2 pcs. in laminated strips, 6 strips in a cardboard box).
Each pack also contains instructions for using Panadol extra.
In one coated tablet and in one soluble tablet, the content of active components is: paracetamol - 500 mg, caffeine - 65 mg.
Pharmacological properties
Pharmacodynamics
Panadol extra is a combined preparation of the anilide group, which has antipyretic and analgesic effects.
The pharmacological action is due to the following properties of the active ingredients that make up Panadol extra:
- paracetamol: inhibiting the synthesis of prostaglandins, it helps to reduce the excitability of the heat center and increase heat transfer;
- caffeine: stimulates the central nervous system; its action provides an increase in the permeability of the blood-brain and other histohematological barriers, which leads to an increase in the concentration of paracetamol in the brain tissues and an increase in the analgesic effect.
The drug does not irritate the mucous membrane of the gastrointestinal tract (GIT), has good tolerance.
Pharmacokinetics
After oral administration, the active ingredients are well absorbed in the digestive tract.
Paracetamol and caffeine are evenly distributed in tissues and penetrate into the brain.
Metabolism takes place in the liver.
Paracetamol and caffeine are excreted unchanged and in the form of metabolites mainly through the kidneys.
Indications for use
The use of Panadol Extra is indicated in the following conditions:
- weak or moderate severity of pain syndrome of various origins (migraine, headache, toothache, myalgia, neuralgia, back pain, muscle and rheumatic pain);
- colds, flu, tonsillitis - in order to lower body temperature, relieve pain, relieve the condition.
Contraindications
Absolute:
- simultaneous use of other paracetamol-containing agents;
- period of pregnancy;
- breast-feeding;
- age up to 12 years;
- hypersensitivity to the components in Panadol extra.
The drug should be taken with caution in patients with severely impaired liver and / or kidney function.
Panadol extra, instructions for use: method and dosage
Film-coated tablets
Panadol extra coated tablets are taken orally with plenty of water.
Recommended dosage: 2 pcs. with an interval of at least 4 hours.
The maximum daily dose is 8 pcs.
Soluble tablets
The finished solution of the drug is taken orally, after dissolving the tablets in 100 ml of water.
Recommended dosage: 2 pcs. 1-4 times a day. Break between receptions - at least 4 hours.
The maximum daily dose is 8 pcs.
Without a doctor's prescription, the duration of the course of taking the drug as an anesthetic is no more than 5 days, antipyretic - no more than 3 days.
Side effects
Against the background of taking the combined drug, it is possible to develop allergic reactions in the form of skin rashes.
Overdose
A significant excess of the dose of the drug may be accompanied by an increase in blood pressure (BP), impaired renal and liver function.
Symptomatic therapy is used to relieve signs of drug overdose.
special instructions
During the period of taking Panadol extra, it is recommended to limit the use of tea or coffee.
It should be borne in mind that with alcoholic liver diseases of a non-cirrhotic nature, the risk of overdose increases in patients.
Application during pregnancy and lactation
The use of Panadol extra is contraindicated during pregnancy and lactation.
Pediatric use
Do not use Panadol extra tablets to treat children under 12 years of age.
With impaired renal function
It is recommended to take the drug with caution in case of severe renal dysfunction.
For violations of liver function
It is recommended to take Panadol extra with caution in case of severe liver dysfunction.
Drug interactions
With the simultaneous use of Panadol extra with other drugs, the following reactions may develop:
- indirect anticoagulants: enhance their effect;
- metoclopramide, domperidone: increase the absorption of the active components of the drug;
- cholestyramine: combined administration helps to reduce the absorption of paracetamol and caffeine;
- ethanol: the use of alcoholic beverages and ethanol-containing medicines is contraindicated.
Analogs
The analogues of Panadol extra are Migrenol, Migrenium, Solpadein Fast, Strike Plus, etc.
Terms and conditions of storage
Keep out of the reach of children.
Store at temperatures up to 25 ° C.
Shelf life is 4 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Panadola extra
Reviews about Panadol extra in the form of film-coated tablets are positive. Patients indicate the efficacy of the drug, a quick analgesic effect and the absence of adverse events. In addition, a wide spectrum of action is noted for pain syndrome.
Patients' dissatisfaction is caused by the lack of the drug on sale.
Price for Panadol extra in pharmacies
The price for Panadol extra has not been established due to the lack of the drug in the pharmacy chain.
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
