Cyclodinone
Cyclodinone: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Drug interactions
- 11. Analogs
- 12. Terms and conditions of storage
- 13. Terms of dispensing from pharmacies
- 14. Reviews
- 15. Price in pharmacies
Latin name: Cyclodynon
ATX code: G02CX
Active ingredient: common prutnyak fruit extract (Vitex agni casti fructuum extract)
Manufacturer: Bionorica CE (Germany)
Description and photo updated: 2018-26-11
Prices in pharmacies: from 443 rubles.
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Cyclodinone is a herbal remedy that has a dopaminomimetic effect.
Release form and composition
- film-coated tablets: round, biconvex, with a matte surface, greenish-blue color (15 pcs. in blisters, in a cardboard box 2 or 4 blisters);
- drops for oral administration: transparent liquid of yellow-brown color with the smell of common barnacle fruits, during its storage a slight sediment may fall out (50 and 100 ml in vials, 1 vial in a cardboard box).
Composition of 1 coated tablet:
- active substance: dry extract of common barnacles (Agnus castus) - 3.2-4.8 mg (corresponds to 40 mg of medicinal plant materials);
- auxiliary components: microcrystalline cellulose, lactose monohydrate, colloidal silicon dioxide, magnesium stearate, povidone, potato starch;
- shell composition: copolymer of methacrylic and ethacrylic acids, macrogol 6000, titanium dioxide (IV) (E 171), talc, indigotine (E 132), iron oxide yellow (E 172).
Composition of 100 g drops for oral administration:
- active substance: dry extract of common rod (Agnus castus) - 0.192-0.288 g (corresponds to 2.4 g of medicinal plant materials);
- auxiliary components: sodium saccharate dihydrate, sorbitol 70% (non-crystallizing), ethanol 96%, polysorbate 20, povidone, purified water, peppermint flavor.
Pharmacological properties
Pharmacodynamics
The components of Cyclodinone help to normalize the concentration of sex hormones.
The drug causes a decrease in prolactin production, which eliminates hyperprolactinemia. Due to the increased concentration of prolactin, the secretion of gonadotropins is disrupted, which can lead to disruption of follicular maturation, ovulation and the formation of the corpus luteum. In the future, this leads to an imbalance between progesterone and estradiol, which is fraught with menstrual irregularities and the development of mastodynia. Prolactin, unlike estrogens and other hormones, also has a direct stimulating effect on proliferative processes in the mammary glands, causing the expansion of the milk ducts and enhancing the formation of connective tissue. With a decrease in the content of prolactin, the reverse development of pathological processes in the mammary glands occurs, the pain syndrome is stopped. With the rhythmic production and normalization of the ratio of gonadotropic hormones, the second phase of the menstrual cycle is normalized.
Indications for use
- premenstrual syndrome;
- menstrual irregularities;
- mammalgia.
Contraindications
According to the instructions, Cyclodinone is contraindicated in case of hypersensitivity to its components.
Due to the ethanol content in the form of drops, the drug is not recommended for patients who have undergone successful treatment for alcoholism.
Instructions for the use of Cyclodinone: method and dosage
The drug should be taken orally in the morning: tablets - swallow whole and wash down with water, drops - with a little water. Shake the bottle of liquid before taking it.
Usually prescribed 1 tablet or 40 drops 1 time per day. The duration of the therapeutic course is at least 3 months (without a break for the time of menstruation). After the condition improves and the unpleasant symptoms disappear, it is recommended to continue taking the drug for several more weeks. If, after discontinuation of Cyclodinone, the symptoms recur, a doctor's consultation is required.
Side effects
In rare cases, Cyclodinone causes allergic skin reactions. There are isolated reports of the development of transient psychomotor agitation, hallucinations and confusion.
Overdose
To date, no cases of overdose have been reported.
special instructions
Cyclodinone tablets contain milk sugar (lactose) - it can cause diarrhea and pain in the epigastric region.
In both dosage forms, the drug can be prescribed to patients with diabetes mellitus, since a single dose contains less than 0.03 XE.
In case of menstrual irregularities, the development of pain in the mammary glands, weakness and / or depression, you should seek the advice of your doctor.
When stored in a bottle with drops, a slight sediment may fall out. This phenomenon does not affect the effectiveness of the drug.
Influence on the ability to drive vehicles and complex mechanisms
The components of Cyclodinone drops and tablets do not adversely affect the cognitive and psychophysical functions of a person.
Application during pregnancy and lactation
Cyclodinone should not be used during pregnancy and lactation.
Drug interactions
With the simultaneous use of dopamine receptor antagonists, a mutual decrease in effects may be noted.
Cases of interaction with other drugs have not yet been established.
Analogs
Cyclodinone analogues are Agnucaston, Bromcriptine, Mastodinon, Indinol, Prefemin, Mastopol.
Terms and conditions of storage
Store at temperatures up to 25 ° C in a place protected from light, out of reach of children.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Dispensed by prescription.
Reviews of Cyclodinone
Reviews of Cyclodinone are controversial, but more positive. In them, women describe it as an effective remedy that normalizes the menstrual cycle and eliminates the negative symptoms inherent in premenstrual syndrome and mastodynia. Additional benefits include herbal composition and good tolerance. The disadvantages of Cyclodinone are the high cost and long course of treatment.
Negative reviews contain complaints about the lack of the necessary therapeutic effect or the development of side effects, such as a rash on the face (including acne), increased oily skin, hair loss, and weight gain.
The price of Cyclodinone in pharmacies
Approximate prices of Cyclodinone: coated tablets (30 pcs. Per package) - 455-570 rubles, drops for oral administration (1 bottle) - 435-500 rubles.
Cyclodinone: prices in online pharmacies
Drug name Price Pharmacy |
Cyclodinone drops for oral administration 50 ml 1 pc. 443 r Buy |
Cyclodinone film-coated tablets 30 pcs. RUB 481 Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!