Fleet Phospho-Soda
Fleet Phospho-soda: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. In case of impaired renal function
- 12. Use in the elderly
- 13. Drug interactions
- 14. Analogs
- 15. Terms and conditions of storage
- 16. Terms of dispensing from pharmacies
- 17. Reviews
- 18. Price in pharmacies
Latin name: Fleet Phospho-soda
ATX code: A06AD10
Active ingredient: sodium phosphate
Manufacturer: Laboratorios Casen Fleet (Spain)
Description and photo update: 2018-22-10
Fleet Phospho-Soda is a laxative with osmotic properties.
Release form and composition
Dosage form Fleet Phospho-soda - oral solution: transparent, colorless, with a ginger-lemon odor (45 ml in polyethylene bottles, 2 bottles in a cardboard box; 50 and 100 bottles in a cardboard box - packaging for hospitals).
Active substances in 1 ml solution (1 bottle):
- sodium dihydrogen phosphate dihydrate - 542 mg (24.4 g);
- sodium hydrogen phosphate dodecahydrate - 240 mg (10.8 g).
Auxiliary components: sodium saccharin, glycerol 99%, sodium benzoate (E211), purified water, lemon and ginger flavor (citric acid, partially stabilized lemon oil, lemon oil, alcohol, water, ginger oil).
Pharmacological properties
Pharmacodynamics
Fleet Phospho-soda is a saline laxative, the mechanism of action of which is based on the ability to increase water retention in the lumen of the small intestine (using osmotic processes). Due to the accumulation of fluid in the ileum, peristalsis increases and, as a result, the intestines are cleansed.
Pharmacokinetics
The drug has only a local, local effect, so there is no need for pharmacokinetic studies. Sodium phosphate is poorly absorbed in the gastrointestinal tract, however, there is a slight absorption of sodium ions and phosphates, which depends on the dose taken.
Indications for use
- preparation for surgery on the colon;
- preparation for X-ray / endoscopic examination of the colon.
Contraindications
- acute inflammatory bowel disease;
- violation of the integrity of the intestine;
- intestinal obstruction (both complete and partial);
- congenital or acquired megacolon;
- abdominal pain, nausea, vomiting;
- renal failure;
- heart failure;
- age up to 15 years;
- hypersensitivity to drug components.
Instructions for the use of Fleet Phospho-soda: method and dosage
Fleet Phospho-soda is taken orally.
For administration, the contents of one bottle are dissolved in half a glass of cold water (120 ml), drunk and washed down with at least one glass of cold water.
1 bottle = 1 dose.
It is necessary to start taking the drug the day before the X-ray / endoscopic procedure. If the procedure is scheduled for the first half of the day, you must follow the instructions for the morning appointment, if in the afternoon - the instructions for the daytime appointment.
Typically, the drug will cause stools within 30 minutes to 6 hours after ingestion.
Morning appointment, the day before the procedure
Instead of having breakfast at 7 am, drink at least 1 glass of light liquid. These include water, tea, coffee, clear still and carbonated soft drinks, pulpless fruit juices, and solids-free soups.
The first dose of the drug is taken immediately after breakfast.
Instead of lunch at 13 o'clock, at least 3 glasses of light liquid (720 ml) are drunk.
Instead of dinner at 19 o'clock, drink at least 1 glass of light liquid.
The second dose of the drug is taken immediately after dinner.
Light liquids can be consumed until midnight.
Day appointment
On the day before the procedure, a light snack is allowed at 13:00. Do not eat solid food after dinner.
Instead of dinner at 19 o'clock, drink 1 glass or more of light liquid. The first dose of the drug is taken immediately after dinner.
During the evening, you should drink at least 3 glasses of light liquid.
On the day of the procedure, instead of breakfast at 7 am, at least 1 glass of light liquid is drunk. The second dose of the drug is taken immediately after breakfast.
Until 8 o'clock in the morning, light liquids are allowed.
Side effects
- from the digestive system: bloating, abdominal pain, diarrhea, nausea, vomiting; very rarely - single or multiple aft-like formations on the mucous membrane of the sigmoid and rectum (detected during endoscopy, have no clinical significance, disappear on their own without treatment);
- from the nervous system: headache, weakness, asthenia, dizziness;
- from the side of metabolism: in some cases in patients from risk groups - dehydration, electrolyte imbalance (for example, acidosis, hypokalemia, hyperphosphatemia, hypernatremia, hypocalcemia);
- others: allergic reactions.
Overdose
There are several cases of death in children and adults due to hyperphosphatemia with concomitant acidosis, hypernatremia and hypocalcemia after high doses of Fleet Phospho-soda.
Cases of complete recovery after an accidental overdose are also described, including in a patient who took a 6-fold dose of the drug.
special instructions
Fleet Phosphate Soda is not intended to treat constipation.
Patients should be warned about possible frequent and loose stools.
The drug should be used with caution by the elderly, debilitated patients, patients with heart disease, reduced kidney function and colostomy, as well as those on a diet low in salt. These patients are at risk of developing hypokalemia, hypocalcemia, hyperphosphatemia, dehydration associated with hypernatremia / acidosis.
In some cases, during endoscopy on the mucous membrane of the rectum and sigmoid colon, aft-like changes were found: discrete formations of an inflammatory nature, lymphoid follicles or changes caused by taking the drug. These phenomena have no clinical significance, disappear on their own and do not require special treatment.
In rare cases, patients have a prolongation of the QT interval on the electrocardiogram due to electrolyte imbalance such as hypokalemia or hypocalcemia.
Influence on the ability to drive vehicles and complex mechanisms
According to the instructions, Fleet Phospho-soda does not affect the speed of reactions and the ability to concentrate, therefore, it does not require refraining from driving and performing work with potentially dangerous consequences.
Application during pregnancy and lactation
There is insufficient data on the absence of the toxic effect of the drug on the fetus, therefore, Fleet Phospho-soda is contraindicated for pregnant women.
Sodium phosphate passes into breast milk, and therefore breastfeeding women need to stop breastfeeding while taking the drug and within 24 hours after taking the last dose.
Pediatric use
The drug is contraindicated in children under 15 years of age.
With impaired renal function
- renal failure - the drug is contraindicated;
- reduced renal function - the drug should be used with caution.
Use in the elderly
In old age, Fleet Phospho-soda must be used with caution.
Drug interactions
Careful monitoring of the patient's condition is required in the case of the simultaneous use of calcium channel blockers, diuretics, lithium preparations and other drugs that can affect the level of electrolytes, since there is a risk of hypokalemia, hypocalcemia, hyperphosphatemia and dehydration against the background of acidosis / hypernatremia.
Fleet Phospho-soda can delay or prevent the absorption of other drugs taken simultaneously in the gastrointestinal tract, and therefore it is possible to reduce or completely eliminate the effect of regularly used drugs, including oral contraceptives, antibacterial, hypoglycemic and antiepileptic drugs.
Analogs
The analogues of Fleet Phospho-soda are: Fortrans, Defenorm, Fleet Redi-tu-yuz enema, artificial Karlovy Vary salt, Endofalk, Normacol.
Terms and conditions of storage
Keep out of reach of children at temperatures up to 25 ° C.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews of Fleet Phospho-Soda
Reviews of Fleet Phospho-soda are mostly positive: patients note the effectiveness and mild action of the drug, as well as the convenience of its use.
Negative responses include only the occurrence of some side effects, most often nausea.
The price of Fleet Phospho-soda in pharmacies
The price of Fleet Phospho-soda is 515–645 rubles per package of 2 bottles.
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
