Dicloran plus
Dicloran plus: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. In case of impaired renal function
- 12. For violations of liver function
- 13. Use in the elderly
- 14. Drug interactions
- 15. Analogs
- 16. Terms and conditions of storage
- 17. Terms of dispensing from pharmacies
- 18. Reviews
- 19. Price in pharmacies
Latin name: Dicloran Plus
ATX code: M02AA
Active ingredient: diclofenac diethylamine, flax seed oil, methyl salicylate, levomenthol
Manufacturer: Unique Pharmaceutical Laboratories (India)
Description and photo update: 2018-23-10
Prices in pharmacies: from 209 rubles.
Buy
Dicloran plus is a non-steroidal anti-inflammatory drug (NSAID) of a combined composition for external use.
Release form and composition
Dicloran plus dosage form is a gel for external use (10, 30 and 50 g each in aluminum / plastic tubes, 1 tube in a cardboard box).
Active ingredients in 1 g of gel:
- methyl salicylate - 100 mg;
- levomenthol - 50 mg;
- flax seed oil - 30 mg;
- diclofenac diethylamine - 11.61 mg, which corresponds to 10 mg of diclofenac sodium.
Auxiliary components in the gel: propylene glycol, benzyl alcohol, citric acid monohydrate, carbomer 980, butylhydroxytoluene, macrogol glyceryl hydroxystearate (Cremophor RH-40), disodium edetate, butylhydroxyanisole, diethylamine.
Pharmacological properties
Dicloran plus has anti-inflammatory, anti-exudative and analgesic effects.
Pharmacodynamics
Methyl salicylate and sodium diclofenac are NSAIDs, the mechanism of action of which is explained by the ability to suppress the synthesis of prostaglandins. When applied topically, these substances reduce swelling and morning stiffness in joints, inflammation and pain in joints, and increase the number of movements.
Flax seed oil contains alpha-linolenic acid, which has anti-inflammatory properties.
Levomenthol has a mild analgesic and local distracting effect, irritates the nerve endings, a feeling of coolness at the site of application of the gel.
Pharmacokinetics
When applied topically, the active substances of Dicloran plus are absorbed and penetrate into the subcutaneous tissue, muscle tissue and the joint capsule.
Indications for use
- diseases of the musculoskeletal system, including radiculitis, psoriatic arthritis, osteoarthritis of the peripheral joints and spine, ankylosing spondylitis, rheumatoid arthritis, osteochondrosis with radicular syndrome;
- muscle pains of rheumatic and non-rheumatic origin, including those caused by excessive physical exertion;
- rheumatic soft tissue lesions such as bursitis and tendovaginitis;
- post-traumatic inflammation of soft tissues and joints (due to bruises, sprains and overstrain).
Contraindications
- violation of the integrity of the skin;
- complete / incomplete combination of bronchial asthma, recurrent polyposis of the nasal mucosa and paranasal sinuses with intolerance to acetylsalicylic acid (ASA) or other NSAIDs at the present time or in history;
- children under 6 years old;
- III trimester of pregnancy;
- lactation period;
- increased sensitivity to any component of the drug.
Dicloran plus should be used with caution in pregnant women in the I and II trimesters, elderly people, patients with bronchial asthma, severe renal and liver dysfunction.
Instructions for the use of Dicloran plus: method and dosage
Dicloran plus gel is applied externally. The product should be applied to the affected area and rubbed lightly.
A single dose for adults and adolescents from 12 years old depends on the size of the painful zone and is 2–4 g, which corresponds to a strip of gel 4–8 cm long (respectively) in the case of squeezing out the drug with the tube neck completely open. The frequency of application is 3-4 times a day.
Children 6–12 years old can use the drug 1–2 times a day in a single dose of no more than 2 g.
Unless otherwise prescribed by a doctor, the duration of treatment is no more than 10 days. The need for a longer treatment is decided individually.
Side effects
Dicloran Plus can cause the following side effects:
- local: photosensitization, eczema, contact dermatitis (swelling of the treated skin area, peeling, papules, hyperemia, vesicles, itching);
- systemic: allergic reactions (angioedema, urticaria, bronchospastic reactions), generalized skin rash.
Overdose
Subject to the rules of application and dosage of the drug, the systemic absorption of the active ingredients of the gel is extremely low, and therefore an overdose is practically impossible.
Systemic side effects may occur after accidental ingestion of the drug. In this case, it is necessary to artificially induce vomiting, rinse the stomach and take activated charcoal. If required, forced diuresis is performed and symptomatic therapy is prescribed to eliminate the undesirable effects that have arisen. Dialysis is ineffective, since diclofenac is characterized by a high degree of binding to blood plasma proteins (about 99%).
special instructions
The gel can only be applied to the skin without damage, avoiding contact with open wounds, since in this case (due to the resorptive effect) there is a high risk of developing systemic side effects.
Do not allow the drug to come into contact with mucous membranes and eyes. Do not apply under an occlusive dressing.
Influence on the ability to drive vehicles and complex mechanisms
According to the instructions, Dicloran plus does not have the property of negatively affecting the speed of a person's reactions and his ability to concentrate.
Application during pregnancy and lactation
The third trimester of pregnancy is a contraindication to the appointment of Dicloran Plus. The question of the advisability of using the drug in the first and second trimesters is decided by the doctor individually.
The experience of drug treatment during lactation is not enough, therefore, during this period, it is not recommended to carry out therapy using Dicloran Plus.
Pediatric use
The gel is contraindicated in children under 6 years of age. A single dose for children 6–12 years old should not exceed 2 g with a maximum frequency of application 2 times a day.
With impaired renal function
Caution during therapy is required in patients with severely impaired renal function.
For violations of liver function
Caution during the period of therapy is required for patients with severe liver dysfunction.
Use in the elderly
Elderly people should be careful during treatment.
Drug interactions
Diclofenac - one of the active ingredients of Dicloran plus - can enhance the effect of drugs that can cause photosensitization.
There are no clinically significant interactions with other drugs.
Analogs
By the mechanism of action, analogues of Dicloran plus are: Diclofen-gel, Dicloran gel, Diclofenac, Diclac gel, Flamidez gel, Indomethacin Plus, Voltaren Emulgel, Rapten gel, Olfen gel, Ketum-gel, Ketonal cream, Fort-gel, Finalgel, Fanigan Fast, Naproxen, Ketoprofen, Ketorol, Nortafen, Butadion, etc.
Terms and conditions of storage
Store for no more than 3 years out of the reach of children at temperatures up to 30 ° C. Do not freeze.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Dicloran plus
Reviews about Dicloran plus are mostly positive. Many patients consider this drug to be the best of those that contain diclofenac in its composition. Thanks to carefully selected active ingredients, Dicloran Plus quickly relieves pain, warms up and soothes sore joints, relieves pain and swelling during sprains, and helps to fight the complications of osteochondrosis.
As an additional advantage, most patients attribute the relatively low cost of this gel for external use.
Dicloran plus price in pharmacies
The price for Dicloran plus is 180–270 rubles for a 30 g tube.
Dicloran plus: prices in online pharmacies
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Drug name Price Pharmacy |
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Dicloran plus gel for external use 30 g 1 pc. 209 RUB Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
