Piaskledin 300
Piaskledin 300: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews
- 16. Price in pharmacies
Latin name: Piascledine 300
ATX code: M09AX
Active ingredient: avocado oil unsaponifiable compounds (avocado oil) + soybean oil unsaponifiable compounds (soybean oil)
Manufacturer: Laboratoires EXPANSCIENCE (France)
Description and photo update: 2019-19-08
Prices in pharmacies: from 1095 rubles.
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Piaskledin 300 is a herbal medicine that regulates metabolic processes in cartilaginous tissue, which has a symptomatic analgesic and anti-inflammatory effect on joints.
Release form and composition
Dosage form - capsules: type I, with a cap and an opaque white body, marked "P 300"; content - brown paste (15 pcs. in blisters, 1 or 2 blisters in a cardboard box).
Active ingredients in 1 capsule:
- Unsaponifiable compounds of soybean oil - 200 mg;
- Unsaponifiable compounds of avocado oil - 100 mg.
Additional components: colloidal silicon dioxide and butylhydroxytoluene.
Body and lid composition: gelatin, titanium dioxide.
The composition of the binder solution used to seal the capsules: gelatin and polysorbate 80.
Composition of TekPrint SW-9008 Black Ink used for marking capsules: potassium hydroxide, butanol, isopropanol, concentrated ammonia solution, propylene glycol, ethanol, shellac, black iron oxide.
Pharmacological properties
Pharmacodynamics
Piaskledin 300 is a regulator of metabolic processes in cartilage tissue, has anesthetic and anti-inflammatory effect on joints. It helps to slow down degenerative processes in the cartilaginous tissue of the joints, to reduce pain associated with these processes, to restore motor function.
According to the studies, Piaskledin 300 has a regenerating effect on cartilage by stimulating collagen synthesis in articular chondrocytes.
Properties of active ingredients - unsaponifiable compounds of avocado and soybean oils:
- an increase in the production of an inhibitor of an activator of plasminogenesis, which helps to reduce cartilage damage. The effect occurs indirectly through the stimulation of metalloproteinases and by direct influence on cartilage, as a result of which the degradation of proteoglycans is activated and the destruction of cartilage is prevented;
- increased collagen production and inhibition of the stimulating effect of IL-1 on collagenase synthesis;
- regulation of the synthesis of macromolecules of the intercellular substance of the articular cartilage, which stimulate the synthesis of macromolecules of hyaline cartilage and periodontal tissue, which prevents the loss of teeth;
- an increase in the action of transforming growth factor β 1 (TGF) in chondrocytes, which has anabolic properties.
Indications for use
- Complex therapy of osteoarthritis of the hip and knee joints of I-III stages;
- Supportive therapy for periodontitis.
Contraindications
Absolute:
- Pregnancy;
- Lactation;
- Age under 18;
- Hypersensitivity to drug components.
Instructions for the use of Piaskledin 300: method and dosage
Piaskledin 300 should be taken orally 1 capsule 1 time per day with meals, preferably with breakfast. The capsules must be swallowed whole and washed down with a glass of water.
The duration of therapy is 6 months. According to the doctor's prescription, it is possible to increase the duration of treatment and repeat courses.
Side effects
In general, Piaskledin 300 is well tolerated. In some cases, allergic reactions occur. An increase in the activity of hepatic transaminases, the level of bilirubin, alkaline phosphatase and gamma-glutamyl transpeptidase is extremely rare.
Overdose
There is no information.
special instructions
At the beginning of therapy, an analgesic and / or non-steroidal anti-inflammatory drug may be prescribed simultaneously.
Piaskledin 300 does not adversely affect the speed of reactions and the ability to concentrate.
Application during pregnancy and lactation
According to the instructions, Piaskledin 300 is not prescribed during pregnancy / lactation.
Pediatric use
Therapy with Piaskledin for 300 patients under 18 years of age is contraindicated.
Drug interactions
There is no information on the drug interaction of Piaskledin 300 with other drugs / substances.
Analogs
The analogues of Piaskledin 300 are: Rumalon, Alflutop, Teraflex, Artra.
Terms and conditions of storage
Store at a temperature of 15-25 ºС out of the reach of children and protected from light.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Piascledine 300
According to reviews, Piaskledin 300 is an effective drug, although in many cases a slow development of therapeutic action is indicated. The best results are observed when it is used as part of a complex treatment. The advantages also include natural composition, convenient dosing regimen and good tolerance. The main disadvantage is the high cost of the drug.
Price for Piaskledin 300 in pharmacies
The approximate price for Piaskledin 300 (30 capsules) is 1241-1550 rubles.
Piaskledin 300: prices in online pharmacies
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Drug name Price Pharmacy |
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Piaskledin 300 capsules 30 pcs. 1095 RUB Buy |
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Piaskledin 300 capsules 30 pcs. 1377 RUB Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
