Ibuklin Junior - Instructions, Application For Children, Reviews, Price, Analogues

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Ibuklin Junior

Ibuklin Junior: instructions for use and reviews

1. 1. Release form and composition
2. 2. Pharmacological properties
3. 3. Indications for use
4. 4. Contraindications
5. 5. Method of application and dosage
6. 6. Side effects
7. 7. Overdose
8. 8. Special instructions
9. 9. Application during pregnancy and lactation
10. 10. Drug interactions
11. 11. Analogs
12. 12. Terms and conditions of storage
13. 13. Terms of dispensing from pharmacies
14. 14. Reviews
15. 15. Price in pharmacies

Latin name: Ibuclin Junior

ATX code: M01AE51

Active ingredient: ibuprofen + paracetamol (ibuprofen + paracetamol)

Manufacturer: Dr. Reddy's Laboratories (India)

Description and photo updated: 20.11.2018

Prices in pharmacies: from 85 rubles.

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Ibuklin Junior is an anti-inflammatory, antipyretic, analgesic drug.

Release form and composition

Dosage form of Ibuklin Junior - dispersible tablets: round, flat, pink interspersed, have a chamfer and a risk on one side and a fruit-mint smell (10 tablets in a blister, in a cardboard box 1, 2 or 20 blisters).

Composition of 1 tablet:

• active substances: paracetamol - 125 mg, ibuprofen - 100 mg;
• auxiliary components: corn starch, microcrystalline cellulose, sodium carboxymethyl starch (type A), aspartame, lactose, colloidal silicon dioxide, flavorings, talc, glycerol, magnesium stearate, peppermint leaf oil, dye.

Pharmacological properties

Pharmacodynamics

Ibuklin Junior for children is a combined preparation, the action of which is due to the properties of its constituent components.

Paracetamol - has antipyretic and analgesic effects, indiscriminately blocks cyclooxygenase (COX).

Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) that also has analgesic and antipyretic effects. Its effect is due to the inhibition of COX-1 and COX-2 and a violation of the metabolism of arachidonic acid, thereby reducing the amount of prostaglandins (mediators of pain, inflammation and hyperthermic reaction). It has a suppressive effect on the exudative and proliferative phases of inflammation.

The combination of these substances is more effective in comparison with monotherapy with one of them.

Pharmacokinetics

Paracetamol is highly absorbed. Communication with plasma proteins - ˂ 10%. The maximum concentration is 5–20 μg / ml and is reached in 30–120 minutes. Able to cross the blood-brain barrier. Less than 1% of the dose taken is found in human milk. Metabolism of 90–95% of paracetamol occurs in the liver. The half-life is 2-3 hours. It is excreted mainly by the kidneys.

When taken orally, ibuprofen is rapidly and almost completely absorbed from the gastrointestinal tract (GIT). The maximum concentration of the substance is reached in 60-120 minutes. The half-life is about 2 hours. Communication with plasma proteins - ˃ 90%. Ibuprofen slowly penetrates into the joint cavity, accumulates in the synovial fluid, where its concentration is higher than in plasma. It is excreted mainly by the kidneys, as well as with bile.

Indications for use

According to the instructions, Ibuklin Junior is indicated for children from 3 to 12 years old with febrile syndrome, pain of various origins (toothache, sprains, fractures, dislocations), and also as an auxiliary drug in the treatment of tonsillitis and acute infectious and inflammatory diseases of the upper respiratory tract (pharyngitis, tracheitis, laryngitis).

Contraindications

Absolute:

• diseases of the optic nerve;
• aspirin asthma;
• exacerbation of gastric or duodenal ulcer;
• impaired renal or liver function (severe);
• violation of blood clotting (hemophilia, hypocoagulation), hemorrhagic diathesis;
• bleeding of any etiology;
• deficiency of glucose-6-phosphate dehydrogenase;
• age up to 3 years;
• increased sensitivity to the components of the drug, other NSAIDs, acetylsalicylic acid.

Relative:

• arterial hypertension;
• chronic heart failure;
• renal or hepatic impairment;
• hyperbilirubinemia;
• nephrotic syndrome;
• history of peptic ulcer or duodenal ulcer;
• enteritis;
• gastritis;
• colitis;
• bronchial asthma;
• leukopenia and anemia of unknown etiology.

Instructions for use of Ibuclin Junior: method and dosage

Ibuklin Junior is taken orally, after dissolving the tablet in 5 ml (teaspoon) of water. The interval between taking the pills should be at least 4 hours, and in case of impaired renal or liver function, at least 8 hours. It is recommended to divide the daily dose into 2-3 doses.

Recommended daily dosage of Ibuklin Junior for children:

• 3–6 years old with a body weight of 13–20 kg: 3 tablets;
• 6–12 years old with a body weight of 20–40 kg: up to 6 tablets.

The duration of use of the drug without medical supervision as an antipyretic agent should not exceed 3 days, as an anesthetic - 5 days.

Side effects

• digestive system: dyspeptic symptoms, with prolonged use of high doses, a hepatotoxic effect is possible;
• hematopoietic system: thrombocytopenia, pancytopenia, leukopenia, neutropenia, agranulocytosis;
• allergic reactions: urticaria, pruritus, rash.

If these reactions appear, it is recommended to stop taking the drug and seek medical help.

Overdose

Ibuclin Junior overdose symptoms: abdominal pain, nausea, vomiting, diarrhea, anorexia, epigastric pain, lethargy, drowsiness, depression, headache, tinnitus, metabolic acidosis, acute renal failure, coma, lowering blood pressure (BP), bradycardia, tachycardia, atrial fibrillation, respiratory arrest.

Recommended treatment: gastric lavage (within the first hour after administration), intake of activated charcoal, forced diuresis, alkaline drinking, symptomatic therapy aimed at correcting blood pressure and the general condition of the patient. Other methods of treatment are determined individually by the attending physician and depend on the concentration of ibuprofen and paracetamol in the body.

special instructions

The decision to take Ibuclin Junior as an antipyretic drug should be made individually, depending on the severity and tolerance of the febrile syndrome.

Caution should be exercised when using the drug in patients with infectious diseases due to the fact that this can lead to masking of symptoms and complicate the diagnosis.

In order to reduce the risk of developing undesirable effects from the gastrointestinal tract, it is recommended to use the drug in the minimum effective dose, as well as the minimum course.

When using Ibuklin Junior for more than 5 days in a row, it is necessary to monitor the peripheral blood and the functional state of the liver.

To avoid distorting the results of laboratory tests (quantitative determination of glucose, uric acid in the blood serum, 17-ketosteroids), it is recommended to discontinue the drug 48 hours before their start.

Influence on the ability to drive vehicles and complex mechanisms

At the time of taking the drug, it is recommended to refrain from driving vehicles and other complex mechanisms that require the speed of psychomotor reactions.

Application during pregnancy and lactation

The use of Ibuclin Junior during pregnancy is possible only with a minimal course and only if the expected benefit to the mother outweighs the possible risk to the fetus.

Experimental studies have not revealed any embryotoxic, teratogenic and mutagenic effects of the drug components.

If it is necessary to take Ibuclin Junior for a short time during lactation, termination of breastfeeding is usually not required.

Drug interactions

Joint reception of Ibuclin Junior with other NSAIDs is contraindicated.

• paracetamol: the risk of nephrotoxic effects increases;
• glucocorticosteroids, ethanol, corticotropin: the risk of erosive and ulcerative lesions of the gastrointestinal tract increases;
• anticoagulants (direct derivatives of coumarin and indandione), thrombolytic agents (alteplase, anistreplase, streptokinase, urokinase), antiplatelet agents, colchicine: the risk of hemorrhagic complications increases;
• indirect anticoagulants: blood clotting should be monitored;
• insulin, oral hypoglycemic drugs: their hypoglycemic effect is enhanced;
• diuretics, antihypertensive drugs: their effect decreases;
• methotrexate, digoxin, lithium preparations: their concentration in the blood increases;
• caffeine: the analgesic effect of Ibuklin Junior is enhanced;
• cyclosporine, gold preparations: increased nephrotoxicity;
• cefamandol, cefoperazone, cefotetan, valproic acid, plikamycin: the incidence of hypoprothrombinemia increases;
• antacids, cholestyramine: absorption of the drug decreases;
• myelotoxic drugs: contribute to the manifestation of hematotoxicity of Ibuclin Junior.

Analogs

Ibuklin Junior's analogues are: Brustan, Brufika Plus, Next, Nurofen, Khairumat.

Terms and conditions of storage

Store away from light, at a temperature not exceeding 25 ° C. Keep out of the reach of children.

Shelf life is 5 years.

Terms of dispensing from pharmacies

Dispensed by prescription.

Reviews about Ibuklin Junior

Reviews about Ibuklin Junior are mostly positive. Parents note that the drug is effective when other drugs do not help lower the temperature. In addition, it is noted that if the instructions are followed, the effect of Ibuclin Junior comes faster than from other drugs. Side effects include loose stools and abdominal pain.

Price for Ibuklin Junior in pharmacies

The approximate price for Ibuklin Junior is 100 rubles. per pack containing 20 tablets.

Ibuklin Junior: prices in online pharmacies

Drug name Price Pharmacy

Ibuklin Junior 100 mg + 125 mg dispersible tablets for children 20 pcs. RUB 85 Buy

Ibuklin Junior dispersion tablets for children 100mg + 125mg 20 pcs. RUB 97 Buy

Anna Kozlova Medical journalist About the author

Education: Rostov State Medical University, specialty "General Medicine".

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!