Phlebaven
Flebaven: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Drug interactions
- 11. Analogs
- 12. Terms and conditions of storage
- 13. Terms of dispensing from pharmacies
- 14. Reviews
- 15. Price in pharmacies
Latin name: Flebaven
ATX code: C05CA53
Active ingredient: purified micronized flavonoid fraction (diosmin + hesperidin)
Manufacturer: Krka-Rus (Russia)
Description and photo update: 2018-27-07
Prices in pharmacies: from 317 rubles.
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Flebaven is a drug with venotonic and venoprotective action.
Release form and composition
Dosage form - film-coated tablets: capsule-shaped, biconvex, light orange-pink; on the break, the shell and the core are visible - a rough mass from yellow to brownish-yellow (16 pcs. in blisters, in a cardboard box 2, 4 or 6 packages).
Tablet core composition: purified micronized flavonoid fraction, granule substance - 613 mg.
Composition of the substance-ranul:
- active substance: purified micronized flavonoid fraction - 500 mg, including diosmin - 450 mg (90%), other flavonoids in terms of hesperidin - 50 mg (10%);
- additional components: povidone K, microcrystalline cellulose.
Excipients of tablets: talc, magnesium stearate, sodium carboxymethyl starch.
The composition of the film shell: Opadrai orange 03H32599 (propylene glycol, titanium dioxide, hypromellose, talc, dyes of iron oxide red and iron oxide yellow).
Pharmacological properties
Pharmacodynamics
Due to the active substances included in the drug (diosmin + hesperidin), Flebaven has a venotonic and angioprotective effect. Improves the parameters of venous hemodynamics, reduces venous stasis and veins distensibility, reduces capillary permeability and increases their resistance. Influences plethysmographic parameters such as venous compliance, venous capacity and venous emptying time. By reducing the time of venous emptying, the drug increases venous tone.
With a pronounced violation of microcirculation, it increases capillary resistance.
Flebaven is effective in chronic diseases of the veins of the lower extremities and in the treatment of hemorrhoids.
The optimal effect can be achieved by taking at least 2 tablets per day.
Pharmacokinetics
The combination of diosmin + hesperidin undergoes active metabolism (confirmed by the presence of phenolic acids in the urine). It is excreted mainly through the intestines, about 14% of the dose received - by the kidneys. The half-life is 11 hours.
Indications for use
Flebaven is used for the symptomatic treatment of venous lymphatic insufficiency, manifested by pain, a feeling of heaviness in the legs, and leg fatigue.
Also, the drug is prescribed for the symptomatic treatment of acute hemorrhoids.
Contraindications
- lactation period;
- hypersensitivity to any component of the drug.
Instructions for the use of Flebaven: method and dosage
Flebaven is intended for oral administration, the tablets should be taken with food.
With venous lymphatic insufficiency, 2 tablets are usually prescribed per day: the first one - in the middle of the day, the second - in the evening. The duration of treatment is determined individually, the course can last up to 12 months. If the symptoms of the disease recur, the doctor may recommend a second course of therapy.
In acute hemorrhoids, the initial daily dose is 6 tablets: three in the morning and three in the evening. After 4 days, the dose is reduced to 4 tablets per day: two in the morning and two in the evening, the treatment is continued for another 3 days.
Side effects
- from the central nervous system: rarely (from ≥ 1/10000 to <1/1000) - general malaise, headache, dizziness;
- from the digestive system: often (from ≥ 1/100 to <1/10) - nausea, dyspepsia, diarrhea, vomiting; infrequently (from ≥ 1/1000 to <1/100) - colitis; the frequency is unknown (based on the available data, it is not possible to determine the frequency) - abdominal pain;
- on the part of the skin: rarely - skin rash, itching, urticaria; frequency unknown - isolated edema of the eyelids, lips, face, angioedema (in exceptional cases).
Overdose
Overdose cases are unknown. If the recommended dose is significantly exceeded, you should consult a doctor.
special instructions
With an exacerbation of hemorrhoids, Flebaven is not able to replace the specific treatment of other anal disorders. The recommended duration of treatment should not be exceeded. If, after the end of the course, the symptoms do not disappear, it is necessary to contact a proctologist who will select the optimal scheme for further therapy.
In case of venous circulation disorders, in order to achieve maximum effect, it is recommended to combine Flebaven treatment with a healthy (balanced) lifestyle: reduce excess body weight, avoid prolonged standing and exposure to the sun. Walking and, in some cases, wearing special stockings can improve blood circulation.
It is recommended to consult a doctor before starting the use of Flebaven, as well as in cases where no improvement occurs during treatment or the condition worsened.
Influence on the ability to drive vehicles and complex mechanisms
According to the instructions, Flebaven does not affect the patient's ability to drive vehicles, work with complex mechanisms and perform activities that require speed of reactions and / or increased attention.
Application during pregnancy and lactation
In experimental studies on animals, the teratogenic effect of Phlebaven was not revealed. There were also no reports of any side effects of the drug when used during pregnancy.
It is not known whether the active substances of Flebaven are excreted in breast milk, therefore the drug is not recommended to be prescribed during lactation.
Drug interactions
Cases of interaction of Flebaven with other drugs are unknown. However, the doctor should be warned about all drugs taken.
Analogs
There is no information about Phlebaven's analogues.
Terms and conditions of storage
Shelf life - 2 years, subject to the storage conditions recommended by the manufacturer: dry place inaccessible to children, temperature - up to 25 ° C.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews of Flebaven
Most of the reviews about Flebaven are positive: the drug effectively eliminates pain, a feeling of heaviness and fatigue in the legs, and also relieves the symptoms of acute hemorrhoids. However, there are some negative reviews in which patients write that in their case this drug was ineffective or caused side reactions, due to which they had to interrupt the course of treatment.
Price for Flebaven in pharmacies
Approximate prices for Phlebaven: 32 tablets per pack - 500-640 rubles, 64 tablets per pack - 775-1200 rubles.
Flebaven: prices in online pharmacies
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Drug name Price Pharmacy |
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Flebaven 50 mg + 450 mg film-coated tablets 32 pcs. 317 r Buy |
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Phlebaven tablets p.p. 500mg 32 pcs. 601 RUB Buy |
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Flebaven 50 mg + 450 mg film-coated tablets 64 pcs. RUB 676 Buy |
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Phlebaven tablets p.p. 500mg 64 pcs. 1153 RUB Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
