Proproten-100
Proproten-100: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacodynamics and pharmacokinetics
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application with alcohol
- 10. Drug interactions
- 11. Analogs
- 12. Terms and conditions of storage
- 13. Terms of dispensing from pharmacies
- 14. Reviews
- 15. Price in pharmacies
Latin name: Proproten-100
ATX code: N07BB
Active ingredient: Antibodies to brain-specific protein S-100
Producer: LLC NPF MATERIA MEDICA HOLDING, Russia
Description and photo update: 2019-05-08
Prices in pharmacies: from 152 rubles.
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Proproten-100 is a drug for the treatment of alcohol dependence, relieves somatovegetative disorders and psychopathological disorders caused by hangover syndrome.
Release form and composition
Dosage forms:
- Homeopathic drops for oral administration: clear, colorless liquid with the smell of alcohol (25 ml each in dark glass vials with a dropper (dosing device) and a lid that provides control of the first opening, in a cardboard box 1 bottle);
- Lozenges: from almost white to white, flat-cylindrical, with a bevel, on one side there is a dividing line and the inscription "MATERIA MEDICA", on the other - "PROPROTEN 100" (20 tablets in a blister strip, in a cardboard box 1, 2 or 5 packs).
The active substance is affinity purified antibodies to the brain-specific protein S-100:
- 1 g drops: 10 mg;
- 1 tablet: 3 mg.
Auxiliary components:
- Drops: 95% ethyl alcohol, purified water;
- Tablets: lactose monohydrate, magnesium stearate, microcrystalline cellulose.
Pharmacodynamics and pharmacokinetics
Proproten-100 modifies the functional activity of the S-100 protein, which correlates information and metabolic processes in the brain. The active components of the drug help to normalize modulations of synaptic plasticity of neurons and improve the synthesis of the neuronal membrane. The consequence of this is the regeneration of the functions of the brain structures, the hypothalamus, the elimination of the formed alcohol dependence, etc.
The drug has a normalizing effect on the system of positive emotional reinforcement, which minimizes the risk of self-stimulation of the lateral hypothalamus.
The drug reduces the activity of hippocampal neurons and helps to reduce the number of circulating immunocomplexes in the blood. During therapy, there is a direct correlation between taking the drug and a decrease in the volume of ethanol consumed. The use of Proproten-100 enhances the inhibitory effects of GABA in the central nervous system, and also restores conditioned reflex functions and neurotransmitter balance. At the same time, the resistance of the brain to the phenomena of hypoxia and toxic effects increases.
The drug is used to relieve symptoms expressed in psychopathological disorders: strong craving for alcohol, anxiety, irritability, anxiety, insomnia, mental stress, mood swings. During therapy, manifestations of such somatovegetative disorders, such as digestive disorders, weakness, increased sweating, tachycardia, tremors, and headache, completely disappear or decrease. Proproten-100 is actively used to reduce or eliminate the signs of alcoholic hangover syndrome. The likelihood of recurrence of this condition is negligible.
Indications for use
The use of Proproten-100 is indicated for monotherapy of alcohol withdrawal syndrome (alcohol withdrawal syndrome) of mild to moderate severity.
Contraindications
- The period of pregnancy and breastfeeding;
- Individual intolerance to the components of the drug.
Instructions for use of Proproten-100: method and dosage
Homeopathic oral drops
Drops are taken orally, dissolving in a tablespoon of water, between meals.
Recommended dosage regimen:
- Hangover: 10 drops every 0.5 hours for the first 2 hours, then at 1 hour intervals for the next 8-10 hours. If the patient falls asleep, then after waking up, the reception should be resumed. With the onset of improvement, the interval between doses is increased to 2-3 hours (4-6 times a day) and the use of the drug is continued for 2-3 days;
- Prevention of relapses: 10 drops 1-2 times a day for 2-3 months. If alcohol is consumed during the treatment period, an additional 10 drops should be taken during the day and at night.
Lozenges
The tablets are taken sublingually (placed under the tongue until completely dissolved) between meals.
Recommended dosage:
- Hangover syndrome: 1 pc. every 0.5 hours during the first 2 hours, then with an interval of 1 hour, 1 pc. 8-10 times. If sleep occurs during this period, treatment should be continued after awakening. After improvement of the condition, the interval of honey should be increased in doses up to 2-3 hours (4-6 tablets per day) and therapy should be continued for 2-3 days;
- Relapse prevention: 1-2 pcs. per day, the course of treatment is 2-3 months, in case of alcohol consumption during the specified period, you must additionally take 1 tablet in the afternoon and in the evening before bedtime.
In case of aggravation of alcohol withdrawal symptoms, additional simultaneous intake of traditional detoxification agents is required.
Side effects
The drug can cause hypersensitivity reactions in patients with intolerance to the components of the drug.
Overdose
Overdose cases in clinical practice are currently unknown. However, with hypersensitivity to the components of the drug, taking it can provoke dyspeptic disorders.
special instructions
According to the instructions, Proproten-100 helps relieve mental stress, feelings of anxiety, irritability, anxiety, normalizes sleep and mood, and reduces the craving for alcohol. In addition, the drug has a therapeutic effect for headaches, indigestion, weakness, tremors, tachycardia, sweating and other disorders caused by alcohol hangover.
Application with alcohol
The drug weakens the effect of alcohol and the manifestations of a hangover syndrome. When using it to eliminate craving for alcohol, it is necessary to abandon alcohol-containing drinks and medicines.
Drug interactions
The use of the drug does not affect concomitant therapy with other drugs.
Analogs
An analogue of Proproten-100 is Tenoten.
Terms and conditions of storage
Store at temperatures up to 25 ° C out of reach of children.
Do not freeze the drops, keep the tablets away from light.
Shelf life: drops - 2 years, tablets - 3 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Proprotene-100
Reviews about Proprotene-100 are few and far between. The affordable price of the drug for most population groups is noted. Noteworthy is the published results of a study in which different forms of the drug were used to treat different patients. Scientists claim that Proproten-100 drops work the fastest. However, opinions are also known according to which taking pills is no less effective.
Approximately 50% of patients after treatment with the drug speak of an improvement in their health, 40% note a weak positive effect, and 6% of patients claim that the use of Proproten-100 in their case was useless.
According to doctors, in addition to taking the drug, the patient's desire to get rid of his addiction to alcohol is important. In the case of Proproten-100, one cannot fail to note the positive results of therapy with it, however, in many cases, additional drugs are required.
Price for Proproten-100 in pharmacies
The price for Proproten-100 in the form of tablets is on average 170-200 rubles (per pack 20 pcs.) Or 310-350 rubles (per pack 40 pcs.). You can buy a 25 ml bottle of homeopathic drops in pharmacies for 280–320 rubles.
Proproten-100: prices in online pharmacies
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Drug name Price Pharmacy |
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Proproten-100 resorption tablets 20 pcs. 152 RUB Buy |
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Proproten-100 tablets homeopath. 20 pcs. 206 r Buy |
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Proproten-100 drops for oral administration 25 ml 1 pc. 231 RUB Buy |
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Proproten-100 resorption tablets 40 pcs. 286 r Buy |
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Proproten-100 drops for internal approx. 25ml 321 r Buy |
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Proproten-100 tablets homeopath. 40 pcs. 332 RUB Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
