Plaquenil - Instructions, Reviews, Analogues

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Plaquenil

Instructions for use:

1. 1. Pharmacological action
2. 2. Release form
3. 3. Indications for use
4. 4. Instruction method of application
5. 5. Side effects
6. 6. Contraindications
7. 7. Analogs
8. 8. Terms of dispensing from pharmacies

Prices in online pharmacies:

from 495 rub.

Buy

Plaquenil is an immunosuppressant drug used to treat malaria.

pharmachologic effect

Plaquenil relieves inflammation, suppresses malaria pathogens, has a strong immunosuppressive effect (inhibits the activity of the immune system).

The active substance of the drug is hydroxychloroquine.

Release form

Pills.

Indications for Plaquenil's use

Plaquenil according to the instructions is prescribed for juvenile and common rheumatoid arthritis, systemic, discoid lupus erythematosus.

There are reviews about Plaquenil, which is successfully used to treat and prevent acute attacks of malaria, provoked by such Plasmodium strains: vivax, malariae, ovale, falciparum.

Plaquenil's analogs are prescribed for the same indications.

Plaquenil instruction: method of application

Plaquenil is recommended to be washed down with 200 ml of milk or taken with meals.

The drug for rheumatoid arthritis in adults, incl. elderly patients are prescribed at a dosage of 6.5 mg / kg, while for the calculation they take not the real, but the ideal weight. The maximum permissible dosage is 400 mg per day.

Plaquenil is given to children, also calculating the dosage by weight - 6.5 mg per kilogram, but it should be taken into account that children weighing less than 31 kg should not be given more than 200 mg of the drug.

With arthritis, Plaquenil can be combined with salicylates, non-steroids, glucocorticosteroids, methotrexate, while their dosage can be reduced: the dosage of cortisone can be reduced by 5-15 mg; the dosage of hydrocortisone is 5-10 mg; triamcinolone or methylprednisolone - 1-2 mg; dexamethasone - 0.3-0.5 mg; prednisone and prednisolone - by 1-2 mg.

With lupus erythematosus, adults are given 400 mg of Plaquenil per day. The frequency of application of the agent is 1-2 times a day.

To prevent acute malarial attacks that occur with a disease caused by strains of Plasmodium malariae or falciparum, the drug is prescribed in a dosage of 400 mg. The medicine is taken weekly, preferably on the same days of the week.

For children with malaria, Plaquenil is prescribed at a dosage of 6.5 mg / kg, but it is taken into account that a child's dosage cannot exceed an adult.

Malaria prophylaxis begins two weeks before entry into a country considered endemic. If this is not possible, adults are prescribed a double loading dose of Plaquenil - 800 mg. In this case, children are given a medicine at the rate of 12.9 mg / kg. Take the daily dosage in two doses with a break of 6 hours. After leaving the area with an increased risk of contracting malaria, prevention should be continued for another two months.

If an acute attack of malaria begins, adults are given 800 mg of Plaquenil, after 6-8 hours - 400 mg, and another 400 mg of the drug over the next two days.

There are good reviews of Plaquenil from patients who took a single, boosted dose of 800 mg during an acute malarial attack.

Children with an acute attack of malaria are given 32 mg of Plaquenil per kilogram of weight for three days.

Side effects of Plaquenil

Plaquenil and drug analogues can cause neuromyopathy and myopathy, headache, psychosis, seizures, emotional lability, psychosis, hearing loss, accommodation disturbance, corneal opacity or edema, tinnitus, retinopathy, blurred vision, keratopathy, optic atrophy, AV block, myocardial hypertrophy, impaired appetite, aplastic or hemolytic anemia, liver dysfunction, vomiting, neutropenia, skin rash, abdominal pain.

There are reviews of Plaquenil from patients who took it, complaining of drug-induced baldness, skin pigmentation disorders, itching, exacerbation of psoriasis, increased photosensitivity of the skin.

With the wrong use of Plaquenil and an overdose, side effects may increase. Exceeding the dose for children is especially dangerous - 1-2 g of the medicine can lead to death. Treat hydroxychloroquine poisoning by gastric lavage, activated carbon, ammonium chloride, and diuresis.

Contraindications

Plaquenil according to the instructions is contraindicated in hypersensitivity to hydroxychloroquine, lactating, pregnant women.

Long-term therapy with Plaquenil and analogs of the drug is contraindicated for children, since their active substance tends to accumulate in the body.

Patients with retinopathy, suffering from suppression of hematopoiesis in the bone marrow, psychosis, psoriasis, porphyria, renal or hepatic insufficiency, hepatitis, lack of glucose-6-phosphate dehydrogenase, should take Plaquenil under supervision.

Analogs

Plaquenil's analogs are: Delagil, Immard, Hydroxychloroquine, Plazmotsid, Plazmokhin, Quinocid, Primahine.

Terms of dispensing from pharmacies

Dispensed by prescription.

Plaquenil: prices in online pharmacies

Drug name Price Pharmacy

Plaquenil 200 mg film-coated tablets 60 pcs. 495 RUB Buy

Plaquenil tablets p.o. 200mg 60 pcs. RUB 525 Buy

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!