Pantogam asset
Pantogam asset: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. In case of impaired renal function
- 12. Drug interactions
- 13. Analogs
- 14. Terms and conditions of storage
- 15. Terms of dispensing from pharmacies
- 16. Reviews
- 17. Price in pharmacies
Latin name: Pantogam activ
ATX code: N06BX
Active ingredient: D-, L-hopantenic acid (D-, L-hopantenic acid)
Producer: PIK-PHARMA PRO (Russia), TsNKB FSUE (Russia)
Description and photo update: 2018-23-10
Prices in pharmacies: from 444 rubles.
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Pantogam active is a drug with an anticonvulsant, nootropic effect.
Release form and composition
Dosage form of Pantogam active release - capsules: gelatinous solid; the capsules contain a white with a yellowish tinge or white powder; 200 mg each - yellow, size No. 1; 300 mg - white, size No. 0 (in polymer cans of 30, 50 or 60 pcs., in a cardboard bundle 1 can; 10 pcs. in blisters, in a cardboard bundle of 3 or 6 packs; 15 pcs. in blisters, in a cardboard box 2 or 4 packages).
Composition of 1 capsule:
- active substance: D-, L-hopantenic acid - 200/300 mg;
- auxiliary components: magnesium stearate - 1.02 / 1.53 mg; microcrystalline cellulose - 13.98 / 20.97 mg.
Shell composition:
- capsules Pantogam active 200 mg: gelatin, glycerol, nipagin, nipazol, sodium lauryl sulfate, titanium dioxide, yellow iron oxide, purified water;
- capsules Pantogam active 300 mg: titanium dioxide - 2%; gelatin - up to 100%.
Pharmacological properties
Pharmacodynamics
The effect of the drug is due to the presence in its structure of gamma-aminobutyric acid (GABA), which directly affects the GABA B receptor-channel complex.
Pantogam active is a racemic mixture of equal amounts of the R-form of hopantenic acid and its S-isomer. Thanks to the isomer, the transport and interaction of the substance with the GABA receptor improves.
Pantogam active, in comparison with the first generation hopantenic acid preparations, has a more pronounced anticonvulsant and nootropic effect.
Main effects:
- stimulation of anabolic processes in neurons;
- increasing the resistance of the brain to the effects of toxic substances and hypoxia;
- providing a moderate sedative effect with a mild stimulating effect, as well as antiasthenic and mild anti-anxiety action;
- decrease in motor excitability, streamlining of behavior;
- inhibition of the pathologically increased detrusor tone and gallbladder reflex;
- activation of mental activity and performance.
Pharmacokinetics
It is rapidly absorbed from the gastrointestinal tract. Penetrates the blood-brain barrier.
It is not metabolized, excreted over 48 hours unchanged: with urine - about 70% of the dose taken, with feces - about 30%.
Indications for use
- cerebrovascular insufficiency associated with atherosclerotic changes in the vessels of the brain;
- extrapyramidal hyperkinesis (Huntington's chorea, myoclonus epilepsy, Parkinson's disease, hepatolenticular degeneration, etc.), extrapyramidal syndrome caused by taking antipsychotics;
- cognitive impairment against the background of organic brain lesions (including the consequences of traumatic brain injuries and neuroinfections) and neurotic disorders;
- psycho-emotional overload, decrease in physical and mental performance, concentration, memory and attention;
- epilepsy (in combination with drugs with an anticonvulsant effect);
- schizophrenia (in combination with other drugs);
- neurogenic disorders of urination, including urgency, pollakiuria, enuresis, urinary incontinence.
Contraindications
- acute severe kidney disease;
- age up to 18 years;
- pregnancy and lactation;
- individual intolerance to the components of the drug.
Instructions for use Pantogama active: method and dosage
Pantogam active is taken orally, preferably in the morning and afternoon, 15–20 minutes after eating.
The drug is prescribed 2-3 times a day, 300-900 mg. The maximum daily dose is 2400 mg.
The average duration of admission is from 1 to 4 months, in some cases longer use is required - 6–12 months. A second course can be prescribed in 3–6 months.
Side effects
Possible violations: rarely - allergic reactions in the form of rhinitis, conjunctivitis, skin rashes (drug withdrawal is required); very rarely - side reactions from the central nervous system in the form of sleep disturbances or drowsiness, headache, dizziness, noise in the head (dose reduction is indicated).
Overdose
The main symptoms: increased symptoms of adverse reactions.
Therapy: activated charcoal, gastric lavage, symptomatic treatment.
special instructions
When carrying out long-term therapy, it is not recommended to combine Pantogam active with other stimulating the central nervous system and nootropic drugs.
Application during pregnancy and lactation
Pregnancy and lactation are contraindications for therapy.
Pediatric use
The drug is not prescribed to patients under 18 years of age (this is due to the lack of data on the safety / efficacy of its use).
With impaired renal function
According to the instructions, Pantogam asset is not prescribed in the presence of acute severe kidney disease.
Drug interactions
Possible interactions:
- glycine, etidronic acid: enhancing the action of Pantogam active;
- drugs with an anticonvulsant effect: enhancing their effects;
- barbiturates: prolonging their action;
- local anesthetics (procaine): potentiation of their action;
- phenobarbital, carbamazepine, antipsychotics: preventing the development of their adverse reactions.
Analogs
The analogues of Pantogam active are Piracetam, Thiocetam, Phezam, Vinpocetine, Glycine, Nootropil, Lucetam, Cavinton, etc.
Terms and conditions of storage
Store in a place protected from light and moisture at temperatures up to 25 ° C. Keep out of the reach of children.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Dispensed by prescription.
Reviews about Pantogama asset
According to reviews, Pantogam asset has a pronounced nootropic effect. The drug enhances appropriate and physical performance, helps with headaches, improves cerebral circulation, attention and memory under increased stress. The disadvantages usually point to high cost and side effects.
Price for Pantogam asset in pharmacies
The approximate price for Pantogam asset 300 mg (60 pcs. In a package) is 420-540 rubles.
Pantogam asset: prices in online pharmacies
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Drug name Price Pharmacy |
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Pantogam active 300 mg capsules 60 pcs. 444 r Buy |
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Pantogam active capsules 300mg 60 pcs. 526 r Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
