Uroprost-D
Uroprost-D: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Drug interactions
- 10. Analogs
- 11. Terms and conditions of storage
- 12. Terms of dispensing from pharmacies
- 13. Reviews
- 14. Price in pharmacies
Latin name: Uroprost-D
ATX code: G04BX
Active ingredient: Prostate extract
Producer: Altpharm LLC (Russia)
Description and photo update: 2020-04-03
Prices in pharmacies: from 627 rubles.
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Uroprost-D is a drug for the treatment of chronic prostatitis and prostate diseases. It has an organotropic effect on the prostate gland, stimulates the muscles of the bladder, has anti-inflammatory and antiaggregatory effects.
Release form and composition
The drug is produced in the form of rectal suppositories: torpedo-shaped, translucent, colorless, the presence of a yellow or gray tint is possible, marbling, sweating of the blister strip packaging, slight softening of the surface layer, the presence of an air rod or a funnel-shaped depression (5 pcs. In blisters, in cardboard box 1 or 2 packages and instructions for use of Uroprost-D).
1 suppository contains:
- active substance: prostate extract - 30 mg (corresponds to the content of 6 mg of water-soluble peptides);
- auxiliary components: macrogol 1500 (polyethylene oxide 1500), dimethyl sulfoxide.
Pharmacological properties
Pharmacodynamics
Uroprost-D is a drug of animal origin for the treatment of prostate diseases. Its active substance, prostate extract, stimulates the muscles of the bladder, has anti-inflammatory, antiaggregatory and organotropic effects on the prostate gland. It has an immunomodulatory and immunostimulating effect, potentiates the synthesis of antiserotonin and antihistamine antibodies. The components of the prostate extract are cytomedins, which belong to the group of peptide bioregulators, the molecular weight of the peptides is from 1 to 10 kDa. The function of low molecular weight peptides of a paracrine or autocrine nature is to play the role of trans-specific intra- and intercellular messengers.
Peptides of the prostate gland help to reduce the period of blood coagulation and increase the antiaggregatory activity of the vascular wall, improve blood microcirculation, increase the fibrinolytic activity of the blood and increase the contractile activity of detrusor myocytes.
In the treatment of chronic prostatitis, the ability of peptide bioregulators to influence the restoration of blood microcirculation and to exert an indirect anti-inflammatory effect due to an increase in the synthesis of antihistamine and antiserotonin antibodies is used.
The use of the drug in benign prostatic hyperplasia is based on the organotropicity of cytomedines - the most important biological effect that allows regulating the functions and processes of cell differentiation in the organ from which they are isolated.
Uroprost-D normalizes the secretory function of epithelial cells, reduces the degree of leukocyte infiltration of the prostate gland and edema, increases the number of lecithin grains in the secretion of acini. It normalizes the parameters of the prostate and ejaculate, prevents the development of venule thrombosis in the prostate gland. Reduces pain and discomfort, stimulates the muscle tone of the bladder, eliminates dysuric phenomena, and improves copulatory function.
Pharmacokinetics
In the body, the peptide preparation is cleaved to amino acids by cellular proteases, and does not accumulate.
Indications for use
The use of Uroprost-D is indicated in the treatment of chronic abacterial prostatitis, benign prostatic hyperplasia, conditions before and after operations on the prostate gland.
Contraindications
The use of rectal suppositories Uroprost-D is contraindicated in case of individual intolerance to the components of the drug (including a history of hypersensitivity to the active substance).
Uroprost-D, instructions for use: method and dosage
Uroprost-D suppositories are used rectally (after moistening them with water), by deep insertion into the anus.
The procedure should be carried out after emptying the rectum as a result of a bowel movement or a cleansing enema.
Recommended dosage: 1 pc. 2 times a day (morning and evening). The duration of treatment is 5-10 days.
If necessary, it is possible to repeat the course, but not earlier than after 14 days.
Side effects
- often: itching in the anus;
- sometimes: flatulence, diarrhea;
- very rare: allergic reactions.
Overdose
Overdose symptoms have not been established.
special instructions
To achieve the desired clinical effect in the treatment of chronic prostatitis, it is recommended to use an integrated approach, involving the use of both non-drug therapy methods and the appointment of various groups of drugs.
After the administration of the suppository, the patient should go to bed for a period of at least 0.5 hours.
The use of the drug must be accompanied by regular analysis of the secretion of the prostate gland.
Influence on the ability to drive vehicles and complex mechanisms
Uroprost-D does not adversely affect the patient's ability to drive vehicles or complex mechanisms.
Drug interactions
With the simultaneous use of rectal suppositories Uroprost-D with other drugs, no negative interaction was noted, therefore the drug is indicated for prescription as part of complex therapy.
Analogs
Uroprost-D analogs are Uroprost, Vitaprost, Vitaprost Forte, Prostakor, Prostatilen, Samprost, etc.
Terms and conditions of storage
Keep out of the reach of children.
Store at temperatures up to 25 ° C.
Shelf life is 2 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Uroprost-D
Reviews of Uroprost-D from patients or specialists are currently absent.
Price for Uroprost-D in pharmacies
The price for Uroprost-D for a package containing 10 suppositories can be approximately 599–695 rubles.
Uroprost-D: prices in online pharmacies
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Drug name Price Pharmacy |
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Uroprost-D 6 mg rectal suppositories 10 pcs. 627 RUB Buy |
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Uroprost-D rectal suppositories. 6mg 10 pcs. 698 r Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
