Sodium sulfacyl-DIA
Sulfacil sodium-DIA: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Drug interactions
- 11. Analogs
- 12. Terms and conditions of storage
- 13. Terms of dispensing from pharmacies
- 14. Reviews
- 15. Price of tria-DIA in pharmacies
Latin name: Sulfacyl sodium-DIA
ATX code: S01AB04
Active ingredient: sulfacetamide (sulfacetamide)
Manufacturer: Diapharm Institute for Molecular Diagnostics, CJSC (Russia)
Description and photo update: 2018-21-11
Prices in pharmacies: from 19 rubles.
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Sulfacil sodium-DIA is a local antimicrobial drug used in ophthalmology.
Release form and composition
Sodium sulfacyl-DIA dosage form - eye drops: transparent, colorless or slightly colored liquid (in a cardboard box 1 or 50 vials / dropper bottles of 5 or 10 ml).
Composition of 1 ml drops:
- active substance: sodium sulfacetamide monohydrate - 100 or 200 mg (in terms of dry matter);
- auxiliary components: sodium disulfite, sodium hydroxide solution 1M, purified water.
Pharmacological properties
Pharmacodynamics
Sodium sulfacil-DIA belongs to the group of antimicrobial bacteriostatic agents (sulfonamide). The mechanism of action is associated with competitive antagonism with PABA (para-aminobenzoic acid) and inhibition of dihydropteroate synthetase. Due to this, there is a violation of the synthesis of dihydrofolic acid and, as a consequence, tetrahydrofolic acid (its active metabolite), which is necessary for the synthesis of pyrimidines and purines.
Shows activity against gram-positive / gram-negative cocci, Bacillus anthracis, Escherichia coli, Actinomyces israelii, Shigella spp., Toxoplasma gondii, Vibrio cholerae, Clostridium perfringens, Corynebacterium diphtheriae, Chlamydia spp.,.
Pharmacokinetics
Sulfacetamide sodium penetrates into the fluids and tissues of the eye. Through the inflamed conjunctiva, it is absorbed into the systemic circulation.
Indications for use
- blepharitis;
- conjunctivitis;
- purulent corneal ulcer;
- chlamydial and gonorrheal eye diseases in adults;
- blenorrhea in newborns (treatment and prevention).
Contraindications
According to the instructions, sodium sulfacil-DIA is contraindicated in the presence of individual intolerance to its components.
It is possible to carry out therapy in women during pregnancy / lactation only under medical supervision after assessing the ratio of the expected benefit with the possible risk.
Instructions for the use of Sulfacil sodium-DIA: method and dosage
Eye drops Sodium sulfacil-DIA are instilled into the conjunctival sac from 5 to 6 times a day, 1-2 drops.
In newborns, in order to prevent blenorrhea, the drug is used in 2 drops in each conjunctival sac immediately after birth and after 2 hours in the same dose.
Side effects
Possible side reactions: lacrimation, burning, itching, pain in the eyes, allergic reactions.
Overdose
Overdose information is not provided.
special instructions
Allergic reactions to sulfacetamide can be observed in patients with hypersensitivity to the following drugs: thiazide diuretics, furosemide, carbonic anhydrase inhibitors, sulfonylurea.
Application during pregnancy and lactation
It is possible to carry out therapy with Sulfacil sodium-DIA eye drops in women during pregnancy / lactation only under medical supervision after assessing the ratio of the expected benefit with the possible risk.
Drug interactions
Possible drug interactions with the following substances / preparations:
- novocaine, dicaine: the bacteriostatic effect of sodium sulfacil decreases;
- silver salts: incompatible with sodium sulfacyl.
Analogs
Sulfacil sodium-DIA analogs are: Sulfacil-sodium-MEZ, Sulfacyl-sodium, Sulfacetamide, Sulfacil, Sulfacil sodium-Vial.
Terms and conditions of storage
Store in a place protected from light at temperatures up to 25 ° C. Keep out of the reach of children. Freezing must not be allowed.
Shelf life is 2 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews of Sulfacil sodium-DIA
According to reviews, Sodium sulfacil-DIA has a low cost and high efficiency. It is also often used not only for the treatment of eye diseases, but also for prolonged purulent rhinitis. Of the shortcomings, they indicate a burning sensation in the eyes when instilled.
The price of Sulfacil sodium-DIA in pharmacies
The approximate price for Sulfacil sodium-DIA (1 bottle of 5 ml of a 20% solution) is 25 rubles.
Sodium sulfacil-DIA: prices in online pharmacies
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Drug name Price Pharmacy |
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Sulfacil sodium-DIA 20% eye drops 5 ml 1 pc. 19 RUB Buy |
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Sulfacil sodium-DIA eye drops 20% vial - drop. 5 ml 28 RUB Buy |
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Sulfacil sodium-DIA eye drops 20% vial - drop. 10ml RUB 39 Buy |
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Sulfacil sodium-DIA 20% eye drops 10 ml 1 pc. RUB 39 Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
