Vaccination
Vaccinia
- Vaccinal disease - observed in a person who does not have immunity to smallpox, moderate intoxication and a local reaction after the introduction of smallpox vaccine;
- A complication of smallpox vaccination, manifested in the form of dermatosis caused by the spread of the smallpox vaccine virus.
Types of vaccines:
- Secondary (secundaria; synonym: inoculated vaccine) - appearing when the vaccinia virus is mechanically transferred to the mucous membrane or to another area of the skin; the symptoms of secondary vaccination are due to its localization;
- Generalized (generalisata) - appearing due to the lymphohematogenous spread of the vaccinia virus, characterized by the spread of roseola over the entire surface of the skin, which successively turn into papules, vesicles, partially into pustules with the formation of crusts that do not leave scars after falling off;
- Creeping (serpiginosa) - characterized by a prolonged course with fever, the formation and centrifugal spread of additional smallpox elements along the edges of the main pockmarks, often combined with them into flat elements having a diameter of 2-3 cm or more, placed on a dense edematous infiltrate;
- Accessory (accessoria) - in which, near the maternal pockmarks, smaller daughter ones appear, sometimes merging with them;
- Progressive (progressiva; synonyms: necrotic vaccine, gangrenous vaccine) - characterized by the formation of a site of necrosis of the skin and underlying tissues, increasing over several months; develops in the presence of immunological deficiency.
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