Duphalac
Instructions for use:
- 1. Composition and form of release
- 2. Pharmacological action
- 3. Indications for use
- 4. Contraindications to use
- 5. Application during pregnancy and lactation
- 6. Method of administration and dosage
- 7. Side effects
- 8. Overdose
- 9. Interaction with other medicinal products
- 10. Special instructions
Prices in online pharmacies:
from 239 rub.
Buy
Duphalac is a lactulose-based pharmacological drug with a laxative effect.
Composition and form of release
Duphalac is available in syrup form. 100 ml of the drug contains 66.7 g of lactulose and purified water to a volume of 100 ml.
According to the instructions, Duphalac is a transparent, viscous liquid of light yellow color.
This drug is produced in plastic bottles of 200, 500 or 1000 ml (including a measuring cup). There is also a form of release in disposable foil and polyethylene bags of 15 ml (10 bags in a box).
pharmachologic effect
This drug has a laxative effect. Duphalac has a hyperosmotic effect, and thus stimulates intestinal peristalsis. It also improves the absorption of phosphates and calcium salts, and favors the elimination of ammonium ions. The intestinal microflora of the large intestine breaks down lactulose to low molecular weight organic acids, contributes to an increase in the volume of intestinal contents. Thus, Duphalac stimulates intestinal peristalsis and affects the consistency of the stool. This leads to the restoration of the physiological rhythm of the emptying of the large intestine and the elimination of constipation.
The use of Duphalac for hepatic encephalopathy or precoma (coma) reduces the content of toxic substances of nitrogen metabolism in the intestine, thereby reducing the negative effect of these substances on the brain.
According to the instructions, Duphalac is a prebiotic, that is, it enhances the growth of beneficial bacteria (bifidobacteria and lactobacilli) and suppresses the growth of pathogenic flora (Clostridia, Salmonella) and shortens the period of bacterial excretion. Thus, this preparation provides a favorable balance of the intestinal microbiocenosis.
According to Duphalac's instructions, the drug has low absorption, after ingestion, it reaches the large intestine unchanged, and there it is split by the microflora. At a dosage of 40-75 ml per day, this drug is completely metabolized. When taking higher doses, the drug is partially excreted unchanged.
Indications for use
Duphalac is used for constipation of a functional origin, as well as for softening stool with hemorrhoids, anal fissures, after operations on the intestines and the anal canal area. This drug is indicated for hepatic encephalopathy or coma (precoma).
According to the instructions, Duphalac is used in the complex treatment of dysbacteriosis, enteritis (at the stage of bacterial carriage) and putrid dyspepsia syndrome in children (as a result of acute food poisoning).
Duphalac is also used to prepare the large intestine for diagnostic examinations (sigmoidoscopy, irrigoscopy, colonoscopy).
Contraindications for use
- Acute intestinal obstruction;
- Galactosemia;
- hypersensitivity to the constituent components of the drug.
According to Duphalac's instructions, it should be used with caution in patients with lactose intolerance, with intestinal bleeding of unknown etiology. Also, the drug should be used with caution in patients with hepatic encephalopathy and diabetes mellitus.
Application during pregnancy and lactation
According to the instructions, Duphalac does not have any effect on the fetus and on the course of pregnancy, it is approved for use during pregnancy. The drug does not pass into breast milk and can be used during breastfeeding.
Method of administration and dosage
This drug is for oral administration. The syrup can be taken undiluted or diluted with water. If Duphalac is prescribed once a day, then it should be drunk at the same time (for example, in the morning during breakfast).
In the treatment of constipation and to soften the stool, the drug is prescribed for adults in an initial dosage of 15-45 ml daily, and then they switch to a maintenance dose of 15-30 ml. The initial dose is selected individually, the drug can be taken once, or be divided into 2 parts. The maintenance dose is selected depending on the response to taking this drug. According to Duphalac's reviews, the therapeutic effect may appear 2-3 days after the start of taking the drug. During treatment with Duphalac, it is necessary to take a sufficient amount of liquid (1.5-2 liters per day).
For children, the dosage of the drug is selected depending on age:
- children 7-14 years old - 10-15 ml per day;
- children 1-6 years old 5-10 ml per day;
- children under one year old - up to 5 ml per day.
Duphalac for newborns is also used in the treatment of constipation and dysbiosis. It is recommended to start taking with 1 ml, gradually increasing the volume of the drug to 4-5 ml (this will help to avoid increased gas formation).
In the treatment of hepatic encephalopathy, the dose of Duphalac is selected individually, usually the initial dosage is 30-45 ml.
To prepare the colon for research, 100-150 ml of the drug is used. Usually, the dosage depends on the type of study, the patient's condition and is selected by the doctor individually. According to reviews, Duphalac for these purposes is best used in combination with other methods of bowel cleansing (for example, cleansing enemas).
Side effect
In the first days of using Duphalac, increased gas formation (flatulence) may appear. It usually disappears after a few days. When taking high doses of the drug, diarrhea occurs. Nausea, vomiting, and abdominal pain may also occur. According to Duphalac's reviews, reports of its side effects are insufficient to accurately estimate the frequency of cases.
If the drug is used in high doses (for example, in the treatment of hepatic encephalopathy), the patient may develop electrolyte imbalances due to diarrhea.
Overdose
When taking high doses of the drug, diarrhea and abdominal pain are possible. Cancellation of the drug or reduction of its dose neutralizes these manifestations. In case of electrolyte imbalance, correction is required by the introduction of electrolyte solutions.
Interaction with other medicinal products
Clinical studies on the interaction of Duphalac with other pharmacological drugs have not been conducted.
special instructions
If there is no effect of taking the drug for several days, you should consult your doctor.
It should be borne in mind that Duphalac may contain a small amount of sugars (for example, lactose, galactose, fructose). When taking a dosage for constipation, this is not a problem for diabetic patients. But when treating hepatic coma (encephalopathy), the sugar content should be taken into account for this group of patients.
Patients with intolerance to galactose, fructose should not use this drug. Duphalac for newborns can only be used under medical supervision.
Duphalac: prices in online pharmacies
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Drug name Price Pharmacy |
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Duphalac 667 mg / ml syrup 15 ml 10 pcs. 239 r Buy |
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Duphalac 667 mg / ml syrup 200 ml 1 pc. 246 r Buy |
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Duphalac syrup 667mg / ml 15ml 10 pcs. RUB 290 Buy |
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Duphalac syrup 667mg / ml 200ml 309 RUB Buy |
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Duphalac 667 mg / ml syrup 500 ml 1 pc. 420 RUB Buy |
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Duphalac plum syrup 667mg / ml fl. 500ml (with measuring cup) 464 r Buy |
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Duphalac 667 mg / ml plum flavored syrup 500 ml 1 pc. 464 r Buy |
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Duphalac syrup 667 mg / ml vial 500ml 477 r Buy |
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Duphalac 667 mg / ml syrup 1000 ml 1 pc. 764 RUB Buy |
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Duphalac syrup 667 mg / ml vial 1000ml 922 RUB Buy |
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Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
