Ursofalk
Instructions for use:
- 1. Pharmacological action
- 2. Release form
- 3. Indications for use
- 4. Contraindications
- 5. Instructions for use
- 6. Side effects
Prices in online pharmacies:
from 150 rubles.
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Ursofalk is a hepatoprotective agent.
Pharmacological action Ursofalk
Ursofalk according to the instructions has a choleretic, destroying cholesterol stones, cholesterol-lowering effect.
The drug protects the membranes of the cells of the liver and biliary tract from damage by toxic bile acids, and also prevents the proliferation of connective tissue in the liver in case of damage to hepatocytes.
Ursofalk contains urodeoxycholic acid. It, as it were, delimits the smallest structures of bile acids with a structural shell - forms the so-called mixed micelles. Urodeoxycholic acid also interacts with lipophilic membrane structures, making them resistant to damage. Thus, it implements a cytoprotective (protective) effect.
A decrease in the content of cholesterol in bile is realized by reducing its reabsorption in the intestine, suppressing the formation in the liver and reducing excretion into bile. In the bile, the content of bile acids increases, due to which cholesterol gallstones dissolve, and new ones are not formed.
Like its counterparts, Ursofalk enhances the secretion of the stomach and pancreas.
The drug has an immunological effect - it affects the content of different classes of immune cells in the body, and at the liver level it slows down the development of fibrosis in patients with cystic fibrosis, primary biliary cirrhosis, alcoholic liver damage, and reduces the likelihood of esophageal varicose veins. There are positive reviews about Ursofalk when it is included in the program for the treatment of malignant diseases of the colon (cancer), it is able to delay the growth of tumor cells.
Release form
Ursofalk is produced in capsules of 250 mg and in suspension (bottles of 250 ml, the content of urodeoxycholic acid is 250 mg / 5 ml).
Indications for use of Ursofalk
The drug is prescribed for the treatment of primary biliary cirrhosis, subject to a compensated condition, biliary reflux gastritis, to dissolve cholesterol stones in the gallbladder and in the case of cholestasis with parenteral nutrition, in the complex treatment of cystic fibrosis, biliary dyskinesias. It is also recommended to prevent the development of colon cancer in high-risk groups for this disease.
There is no age limit. So, the use of Ursofalk as a means of reducing the level of indirect bilirubin in the blood is possible in newborns with conjugated hyperbilirubinemia (jaundice).
Contraindications
According to the instructions, Ursofalk is not used for individual intolerance, in the case of X-ray-positive gallstones (they contain a lot of calcium), for inflammatory diseases of the biliary tract and intestines, decompensated cirrhosis of the liver, non-functioning gallbladder, for disorders in the functioning of the kidneys, liver or pancreas.
Instructions for the use of Ursofalk
The drug is taken once a day (at night) inside. The capsule is swallowed without opening the shell, washed down with water. The average daily dose of Ursofalk is calculated on the patient's body weight and is 10 mg / kg / day. If the dosage exceeds the average, you can divide the daily dose into 2 - 3 doses. Ursofalk suspension is recommended for the treatment of children under 3 years of age and patients weighing less than 34 kg, as well as for swallowing difficulties. It is recommended to take the drug for a long time - from several months to 2 years, without interruptions in treatment.
To dissolve stones in the gallbladder, before starting treatment, make sure that they are cholesterol (they are not visible on the roentgenogram), no more than 20 mm in size, fill the gallbladder no more than half, while maintaining the patency of the biliary tract. Like its analogues, Ursofalk is not recommended to be used simultaneously with drugs that increase cholesterol in bile (clofibrate, estrogens, etc.). Antacids impair drug absorption.
In the case of gallstone disease, the duration of the dissolution of stones is from 6 to 24 months, but if no positive dynamics is noted after 12 months from the beginning of the intake, Ursofalk can be canceled, since further treatment is inappropriate for them. To monitor the effectiveness of treatment, the liver and bile ducts should be examined every six months using ultrasound and X-ray.
With biliary reflux gastritis and reflux esophagitis, the course of administration lasts an average of 10-14 days.
With cystic fibrosis, the daily dose of Ursofalk reaches 20-30 mg / kg / day, with primary biliary cirrhosis up to 15-20 mg / kg / day.
Ursofalk's analogues are Ursosan, Urdoksa and Ursodez.
Side effects
According to reviews, Ursofalk sometimes causes allergic reactions, diarrhea, dyspepsia, calcification of gallstones.
Ursofalk: prices in online pharmacies
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Drug name Price Pharmacy |
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Ursofalk 250 mg capsule 10 pcs. RUB 150 Buy |
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Ursofalk 250 mg capsule 50 pcs. 806 RUB Buy |
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Ursofalk capsules 250mg 50 pcs. 868 RUB Buy |
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Ursofalk 250 mg capsule 100 pcs. 1444 RUB Buy |
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Ursofalk capsules 250mg 100 pcs. 1645 RUB Buy |
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Ursofalk 500 mg film-coated tablets 50 pcs. 1788 RUB Buy |
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
