Dufalak - Instructions For Use, Indications, Contraindications, Reviews

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Dufalak - Instructions For Use, Indications, Contraindications, Reviews
Dufalak - Instructions For Use, Indications, Contraindications, Reviews

Video: Dufalak - Instructions For Use, Indications, Contraindications, Reviews

Video: Dufalak - Instructions For Use, Indications, Contraindications, Reviews
Video: Lactulose ( Duphalac ): What Is Lactulose ? Lactulose Uses - Dosage - Side Effects & ADVICE ! 2023, September


Instructions for use:

  1. 1. Pharmacological action
  2. 2. Release form
  3. 3. Indications for use
  4. 4. Contraindications
  5. 5. Instructions for use
  6. 6. Side effects
  7. 7. Storage conditions

Dufalak is a synthetic laxative used to restore bowel function, treat chronic constipation, and reduce the formation of toxins in liver failure.

pharmachologic effect

The active ingredient of Dufalaka is lactulose, which is synthesized from the lactose of fermented milk products.

It enters the large intestine unchanged, where it interacts with the intestinal flora. By splitting into organic acids in the large intestine, it stimulates peristalsis, eliminating constipation, and also restores the physiological rhythm of bowel emptying. Enhances the growth of lactobacilli and bifidobacteria and inhibits the growth of pathogenic bacteria (E. coli, clostridia), which helps to improve the balance of intestinal flora. Improves the absorption of phosphates and calcium salts, inhibits the growth of Salmonella. Reducing the amount of ammonia in the blood is used in the treatment of liver failure. It is widely used in pediatrics.

Release form

Dufalak is produced in the form of a transparent, viscous, colorless syrup. 100 ml of the preparation contains 66.7 g of lactulose and purified water as an excipient.

In disposable sachets of 15 ml, 10 sachets in a cardboard box; in polyethylene bottles of 200 ml, 500 ml, 1000 ml with a measuring cup included.

Indications for the use of Dufalak

Dufalak is used for:

  • Hepatic encephalopathy;
  • Intestinal dysbiosis;
  • Putrid dispersion syndrome after acute food poisoning in children;
  • Enteritis caused by salmonella;
  • Constipation: to regulate the physiological rhythm of colon emptying; for softening stools for operations in the anus or colon, or for hemorrhoids.


According to the instructions, Dufalak is contraindicated for:

  • Intestinal obstruction;
  • Hypersensitivity to the drug;
  • Metabolic disorders during the conversion of galactose to glucose (galactosemia).

Dufalak is used with caution when:

  • Diabetes mellitus;
  • Lactose intolerance;
  • Hepatic precoma;
  • Undiagnosed rectal bleeding.

Instructions for the use of Dufalak

Duphalac syrup
Duphalac syrup

According to the instructions, Dufalak is taken orally in the morning during meals in a diluted or undiluted form. The dose can be divided into 2 doses.

In the treatment of constipation, as well as to soften the stool for medical purposes, Dufalak is used:

  • Adults - 15-45 ml, maintenance dose - 15-30 ml;
  • Children from 7 to 14 years old - 15 ml, maintenance dose - 10-15 ml;
  • Children from 1 to 6 years old are prescribed an initial and maintenance dose of 5-10 ml;
  • Dufalac for newborns under the age of one year is used in the amount of 5 ml for the initial and maintenance dose. During treatment with the drug, disorders of the emptying reflex may occur.

According to reviews, the effect of the use of Dufalak usually occurs after 2 days. Therefore, the dose can be reduced. If there is no improvement, then the dose or frequency of administration is increased.

In the treatment of shigellosis and salmonellosis, the first 10-12 days, 15 ml are used 3 times a day. After a seven-day break, you should, without changing a single dose, increase the number of doses up to 5 times a day.

In the treatment of hepatic coma and precoma, the initial dose is 30–45 ml 3 times a day. Then the dose is revised individually and selected so that there is soft stool 2-3 times a day. In acute cases, the drug is prescribed in the form of enemas, for which it is diluted in a ratio of 300 ml of the drug to 700 ml of water.

Dufalak for newborns up to 1 year in the treatment of intestinal dysbiosis is prescribed 1.5-3 ml per day. For children from 1 to 3 years old, the dose is 3 ml, from 4 to 7 years old - 5 ml, over 7 years old and adults - 10 ml.

Side effects

According to reviews, Dufalak is well tolerated by both adults and children.

In the early days, flatulence may appear, which usually disappears after a few days. You may also experience nausea, abdominal pain, or vomiting. When using Dufalak in high doses, diarrhea and electrolyte imbalance may occur.

Overdose may cause diarrhea and abdominal pain.

There are no data on the interaction of Dufalak with other drugs.

The drug is safe in the treatment of constipation in diabetes mellitus and does not require additional adjustments.

Dufalak can be used according to indications during pregnancy and lactation.

Storage conditions

Dufalak can be purchased without a prescription.

Shelf life is 3 years.

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!