Berodual
Instructions for use:
- 1. Release form and composition
- 2. Indications for use
- 3. Contraindications
- 4. Method of application and dosage
- 5. Side effects
- 6. Special instructions
- 7. Drug interactions
- 8. Analogs
- 9. Terms and conditions of storage
- 10. Terms of dispensing from pharmacies
Prices in online pharmacies:
from 243 rub.
Buy
Berodual is a drug used in the treatment of bronchial asthma and chronic obstructive bronchitis.
Release form and composition
Berodual is released in the form of a solution for inhalation: a transparent, colorless or almost colorless liquid, free of suspended particles, with a barely perceptible odor (20 ml in dark glass dropper bottles, 1 bottle in a cardboard box).
1 ml (20 drops) contains:
- Active ingredients: anhydrous ipratropium bromide - 0.25 mg, fenoterol hydrobromide - 0.5 mg;
- Auxiliary components: sodium chloride, disodium edetate dihydrate, benzalkonium chloride, hydrochloric acid 1N, purified water.
Indications for use
Berodual is prescribed for the prevention and symptomatic treatment of chronic obstructive respiratory diseases with reversible bronchospasm:
- Bronchial asthma;
- Chronic obstructive bronchitis, uncomplicated or complicated by emphysema.
Contraindications
Absolute:
- Hypertrophic obstructive cardiomyopathy;
- Tachyarrhythmia;
- I and III trimesters of pregnancy;
- Hypersensitivity to the components of the drug.
Relative (the drug should be used with extreme caution due to the increased risk of adverse reactions):
- Closed-angle glaucoma;
- Arterial hypertension;
- Diabetes;
- Myocardial infarction, suffered within the last 3 months;
- Diseases of the heart and blood vessels (aortic stenosis, ischemic heart disease, heart failure, heart disease, severe lesions of peripheral and cerebral arteries);
- Hyperthyroidism;
- Pheochromocytoma;
- Hyperplasia of the prostate;
- Bladder neck obstruction;
- Cystic fibrosis;
- II trimester of pregnancy;
- Lactation period (breastfeeding).
Method of administration and dosage
The drug in the form of a solution for inhalation for relief of seizures is prescribed for adults and children from 12 years old, 20-80 drops (1-4 ml of Berodual). With long-term treatment, lower dosages are used - 20-40 drops (1-2 ml) up to 4 times a day. With moderate bronchospasm or in cases of the need for auxiliary ventilation, 10 drops (0.5 ml of solution) are prescribed.
For children 6-12 years old, Berodual is prescribed once for 10-20 drops (0.5-1 ml) to stop seizures. In severe attacks, an increase in dosage to 40-60 drops (2-3 ml) is permissible. If necessary, long-term therapy, the drug is used up to 4 times a day, 10-20 drops (0.5-1 ml), with moderate bronchospasm - 10 drops (0.5 ml).
In children under 6 years old with a body weight of up to 22 kg, Berodual is used only under medical supervision. The dosage is calculated individually based on body weight, but not more than 10 drops (0.5 ml) 3 times a day.
The solution for inhalation immediately before use must be diluted to a volume of 3-4 ml with physiological solution (it is impossible to dilute with distilled water). Berodual is inhaled through a nebulizer until the solution is completely consumed (within 6-7 minutes). The diluted solution remaining after inhalation cannot be used in the future.
Side effects
- Nervousness, minor tremors, dizziness, headache, disturbance of accommodation, changes in the psyche (central nervous system);
- Rash, urticaria, angioedema of the lips, tongue and face (allergic reactions);
- Tachycardia, palpitations (cardiovascular system);
- Vomiting, nausea (gastrointestinal tract);
- Cough, local irritation, paradoxical bronchospasm (respiratory system);
- Urinary retention, hypokalemia, weakness, increased sweating, convulsions, myalgia (others).
In some cases, when using Berodual in high doses, it is possible to reduce diastolic pressure, increase systolic pressure, and develop arrhythmias. There is also evidence of undesirable effects developing from the organs of vision.
special instructions
If shortness of breath suddenly worsens, you should see a doctor immediately.
It is necessary to prescribe other sympathomimetic bronchodilators simultaneously with Berodual only under medical supervision.
Drug interactions
Since the active component of Berodual is a combination of an m-anticholinergic blocker and a β 2 -adrenomimetic, the following interactions are possible when used in combination with other substances / drugs:
- Anticholinergics for systemic use, other β-adrenergic agonists, xanthine derivatives (including theophylline): may increase side reactions and the bronchodilatory effect of Berodual;
- β-blockers: a significant decrease in the bronchodilatory effect of Berodual is possible;
- Glucocorticosteroids (GCS) and / or cromoglycic acid: increase the effectiveness of treatment;
- Digoxin: an increase in the risk of arrhythmias due to hypokalemia associated with the use of β-adrenergic agonists is likely, in addition, the negative effect of hypokalemia on the heart rate can increase hypoxia (if necessary, such a combination of drugs should regularly check the level of potassium in the blood serum);
- Inhaled halogenated anesthetics (for example, halothane, trichlorethylene or enflurane): may increase the effects of β-adrenergic drugs on the cardiovascular system;
- Xanthine derivatives, corticosteroids and diuretics: it is possible to increase hypokalemia associated with the use of β-adrenergic agonists (it is especially important to take into account this interaction in the treatment of severe forms of obstructive respiratory tract diseases);
- Tricyclic antidepressants and monoamine oxidase (MAO) inhibitors: can enhance the action of β-adrenergic drugs.
Analogs
Berodual's analogs are: Berotex, Berodual N, Ventolin, Duolin, Ipraterol-Nativ, Ipraterol-Aeronativ, Salbroxol, Salbutamol.
Terms and conditions of storage
Store in a dry, dark place out of the reach of children, at a temperature not exceeding 30 ° C. The drug must not be frozen.
The shelf life is 5 years.
Terms of dispensing from pharmacies
Dispensed by prescription.
Berodual: prices in online pharmacies
|
Drug name Price Pharmacy |
|
Berodual 0.25 mg + 0.5 mg / ml solution for inhalation 20 ml 1 pc. 243 r Buy |
|
Berodual N 20 μg + 0.5 mg / dose aerosol for inhalation metered dose 10 ml 1 pc. 445 RUB Buy |
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
