Fenistil Pentsivir
Fenistil Pencivir: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews
- 16. Price in pharmacies
Latin name: Fenistil Pencivir
ATX code: D06BB06
Active ingredient: penciclovir (penciclovir)
Producer: Novartis Pharma Productions, GmbH (Germany)
Description and photo update: 2018-25-10
Prices in pharmacies: from 200 rubles.
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Fenistil Pencivir is an antiviral drug for external and local use.
Release form and composition
Dosage forms of the drug Fenistil Pencivir:
- cream for external use 1%: a homogeneous creamy mass of white color (2 or 5 g in tubes, in a cardboard box 1 tube; a plastic case with a mirror and applicators may be included);
- cream for external use with a toning effect 1%: homogeneous creamy mass, color from beige to brown (2 or 5 g in tubes, in a cardboard box 1 tube).
1 g of cream for external use contains:
- active ingredient: penciclovir - 10 mg;
- auxiliary ingredients: propylene glycol - 416.8 mg; cetostearyl alcohol - 77.2 mg; cetomacrogol 1000 - 9.4 mg; white soft paraffin - 148.5 mg; liquid paraffin (vaseline oil) - 59.4 mg; purified water - 278.7 mg.
1 g of cream for external use with toning effect contains:
- active ingredient: penciclovir - 10 mg;
- auxiliary ingredients: propylene glycol - 415.55 mg; cetostearyl alcohol - 77.2 mg; cetomacrogol 1000 - 9.4 mg; white soft paraffin - 148.5 mg; liquid paraffin (vaseline oil) - 59.4 mg; purified water - 277.45 mg; dye iron oxide red - 1.7 mg; dye iron oxide yellow - 0.8 mg.
Pharmacological properties
Pharmacodynamics
The active component of Fenistil Pencivir - penciclovir - has antiviral efficacy against the varicella-zoster virus (Varicella zoster) and herpes simplex viruses (Herpes simplex) types 1 and 2.
These viruses can be in an inactive form in the body for a long time. Under favorable concomitant conditions, for example, as a result of overwork, colds, acute respiratory infections (acute respiratory viral diseases), influenza, the virus is activated, and it begins to multiply. The external manifestation of the process is the development of blistering rashes (so-called fever or "colds"), mainly on the lips or around them. Due to the use of penciclovir, the virus is blocked, its reproduction stops. Fenistil Pencivir accelerates the healing process, reduces the intensity of pain, and shortens the period of possible transmission of a viral infection.
Pharmacokinetics
Fenistil Pencivir is practically not subject to systemic absorption, provided it is used externally. It is not possible to detect the presence of penciclovir in the blood or urine of healthy volunteers after applying the cream in doses significantly higher than the therapeutic ones.
After penetration into cells affected by the virus, penciclovir is rapidly metabolized into penciclovir triphosphate, which has pharmacological activity and remains in the affected cells for 12 hours.
Indications for use
Fenistil Pencivir is recommended for the topical treatment of recurrent herpes simplex localized on the lips (herpes labialis).
Contraindications
- children under 12 years of age;
- increased individual sensitivity to famciclovir, penciclovir, any other components of the drug.
Instructions for the use of Fenistil Pentsivir: method and dosage
Cream Fenistil Pencivir is applied externally by squeezing a small volume onto a disposable applicator, cotton swab or fingertip and applying to the affected area.
Recommended dosage for adult patients and children over 12 years of age: 1 application every 2 hours (up to 8 times a day). The duration of the therapeutic course is 4 days.
The use of a cream with a tinted effect allows you to mask the areas affected by herpes on the lips and on the skin around them.
Side effects
There may be negative side effects such as burning, tingling or numbness immediately after applying the cream.
Overdose
There is no data.
special instructions
Hands should be thoroughly washed before and after applying the cream.
Therapy should be started as early as possible, with the appearance of the first symptoms of infection. But if this moment is missed, then due to the application of the cream, even at the stage of herpes development in the form of bubbles, the cure time is reduced, the affected areas are healed, the pain sensations decrease and the duration of the peeling of the crust formed during viral exposure is shortened.
If the patient has a weakened immune system or the disease is uncertain, the doctor decides on the need to use Fenistil Pencivir individually.
The cream should be applied exclusively to the herpes-affected areas on and around the lips. It is not recommended to use the drug in the eye area, on the mucous membranes of the mouth, nasal cavity or on the genitals.
A full course of therapy with Fenistil Pencivir cream is required for 4 days to get the maximum effect from the drug (therapy should be continued even after the signs of infection disappear after one to two days of treatment).
In the event of a worsening of the condition, as well as if there is no improvement in well-being after 4 days from the start of therapy, you should consult a doctor.
Influence on the ability to drive vehicles and complex mechanisms
There are no data on the negative effect of Fenistil Pentsivir cream on the speed of psychomotor reactions and the ability to concentrate.
Application during pregnancy and lactation
According to the instructions, Fenistil Pencivir can be used by pregnant and lactating women only under strict indications, provided that the expected benefits of therapy exceed the possible risks to the fetus / child.
Pediatric use
In pediatric practice, the use of the drug for the treatment of children under the age of 12 is contraindicated.
Drug interactions
There is no data.
Analogs
Analogs of Fenistil Pencivir are: Atsivir, Agerp, Atsik, Acyclostad, Acyclovir, Viroleks, Vartek, Herpetad, Gerpevir, Gerpferon, Medovir, Zovirax, Provirsan, etc.
Terms and conditions of storage
Store at temperatures from 0 to 30 ° C (do not freeze). Keep out of the reach of children.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Fenistil Pencivir
According to reviews, Fenistil Pencivir for most patients is a good fast-acting remedy for herpetic eruptions, convenient to use, especially if there is a mirror and applicators in the kit. For some patients, the cream does not help, and they prefer to use other drugs with a similar effect.
As disadvantages, almost all indicate the high cost of the drug.
The price of Fenistil Pencivir in pharmacies
Approximate price for Fenistil Pencivir cream for external use with a toning effect (per tube 2 g) - 336 rubles; cream for external use (per tube 2 g) - 300 rubles.
Fenistil Pencivir: prices in online pharmacies
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Drug name Price Pharmacy |
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Fenistil Pencivir 1% cream for external use 2 g 1 pc. RUB 200 Buy |
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Fenistil Pencivir 1% cream for external use with toning effect 2 g 1 pc. RUB 318 Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
