Famotidine
Instructions for use:
- 1. Pharmacological action
- 2. Indications
- 3. Application
- 4. Side effects
- 5. Contraindications
- 6. Special instructions
- 7. Release form
- 8. Analogs
- 9. Storage conditions
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Famotidine belongs to the group of histamine H2 receptor antagonists and is intended for the treatment of reflux esophagitis and peptic ulcer disease.
pharmachologic effect
Famotidine inhibits the release (secretion) of hydrochloric acid. In addition, this drug reduces the activity of the enzyme that breaks down proteins - pepsin. According to reviews, Famotidine begins to have a therapeutic effect already 45-60 minutes after taking the initial dose. The duration of the drug is determined by the dose taken and ranges from 12 hours to a day.
Indications
- Reflux esophagitis - inflammation of the lining of the esophagus caused by acidic gastric contents;
- Zollinger-Ellison syndrome is a pathological condition in which there is a combination of a gastric ulcer and a benign neoplasm of the pancreas;
- Peptic ulcer of the stomach and duodenum.
The indication for Famotidine is the prevention of the development of peptic ulcer disease in patients who have been undergoing therapy for systemic diseases for a long time using non-steroidal anti-inflammatory drugs (NSAIDs) or glucocorticosteroids.
Famotidine use
The dosage of the drug is selected by the doctor individually. With an exacerbation of peptic ulcer disease, it is usually prescribed once a day at 0.04 g. In some cases, the use of Famotidine twice a day at 0.02 g is justified. The duration of the course of treatment should be from 4 to 8 weeks. After the ulcer defect heals, taking Famotidine is gradually stopped. To prevent subsequent exacerbations, the drug is taken before bedtime at a dose of 0.02 g.
With Zollinger-Ellison syndrome and reflux esophagitis, Famotidine is prescribed four times a day, 0.02 g each.
According to the instructions, Famotidine can also be used to treat patients with impaired renal function. In this case, the daily dose should be reduced in accordance with the values of creatinine clearance.
According to reviews, Famotidine is also effective with increased secretion of hydrochloric acid. In this case, it is prescribed once a day, preferably at bedtime at a dose of 0.02-0.04 g.
Side effects
According to the instructions, Famotidine can lead to the development of the following side effects:
- Dyspeptic symptoms;
- Increased activity of liver enzymes (transaminases);
- Cholestatic jaundice;
- Dizziness and / or headache;
- Disturbances of taste perception;
- Decreased appetite;
- Noise in ears;
- Mental disorders;
- Arthralgia and myalgia;
- Increased body temperature;
- Skin rash;
- Disturbances in the picture of peripheral blood (leukopenia, thrombocytopenia or agranulocytosis). According to reviews, Famotidine in very rare cases can lead to the development of pancytopenia - a sharp decrease in all blood cells;
- Bronchospasm;
- Acne;
- Alopecia areata.
Famotidine contraindications
The use of Famotidine is contraindicated during pregnancy and lactation, as well as if the patient has an individual intolerance to this drug.
special instructions
According to the instructions for Famotidine, it is allowed to prescribe the drug in combination with non-absorbable antacids (drugs that lower the acidity of gastric juice). However, it is necessary that there is an interval of at least two hours between taking these drugs.
Release form Famotidine
Famotidine is available in the form of tablets containing 0.02 g of active substance in a package of 20 pieces. Also, the drug is produced in a higher dosage - 0.04 g each. In this case, in one package - 10 tablets.
Famotidine's analogs
The drug Famotidine has many analogues: Famocid, Famosan, Famonit, Famodin, Famogard, Ulceran, Ulfamid, Topcid, Pepsidin, Nevofarm, Lecedil, Kvamatel, Gastrosidin, Gastrogen, Blokatsid, Atsipen, Antodin, etc.
Despite the fact that a wide range of Famotidine analogues is provided in pharmacies, it is advisable to use exactly the drug that is prescribed to you by your doctor.
Storage conditions
Famotidine belongs to list B and is not intended for treatment without a doctor's prescription. The drug is stored in a dry, dark place out of the reach of children.
Famotidine: prices in online pharmacies
Drug name Price Pharmacy |
Famotidine 20 mg film-coated tablets 20 pcs. RUB 15 Buy |
Famotidine 20 mg film-coated tablets 20 pcs. RUB 17 Buy |
Famotidine 20 mg film-coated tablets 30 pcs. 32 RUB Buy |
Famotidine 40 mg film-coated tablets 20 pcs. 34 rbl. Buy |
Famotidine 20 mg film-coated tablets 20 pcs. RUB 36 Buy |
Famotidine 40 mg film-coated tablets 20 pcs. RUB 39 Buy |
Famotidine 20 mg film-coated tablets 30 pcs. RUB 63 Buy |
Famotidine tablets p.p. 20mg 30 pcs. RUB 65 Buy |
Famotidine 40 mg film-coated tablets 20 pcs. RUB 69 Buy |
Famotidine 40 mg film-coated tablets 30 pcs. RUB 88 Buy |
Famotidine tablets p.p. 40mg 30 pcs. 92 RUB Buy |
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Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!