Euphyllin
Instructions for use:
- 1. Pharmacological properties
- 2. Release form
- 3. Indications
- 4. Contraindications
- 5. Instructions for use
- 6. Side effects
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from 10 rubles.
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Euphyllin is a bronchodilator.
Pharmacological properties
Euphyllin belongs to the group of xanthines. It contains the main active ingredient - theophylline. The drug has an expanding effect on the bronchi, relaxing their smooth muscles and eliminating spasms. In addition, it improves the functioning of the cilia of the epithelium of the respiratory tract, improves the contractions of the diaphragmatic, intercostal and other respiratory muscles. Euphyllin stimulates the respiratory center in the medulla oblongata, improves pulmonary ventilation, oxygen saturation of the blood and reduces the content of carbon dioxide in it, that is, normalizes respiratory function.
The mechanism of action of Euphyllin is to inhibit the phosphodiesterase enzyme, due to which cAMP accumulates in the tissues, the intake of calcium ions into the cells, which are responsible for muscle contraction, decreases, and this relaxes the muscles of the bronchi.
According to the instructions, Euphyllin stimulates cardiac activity, increasing the frequency and strength of myocardial contraction. It is able to reduce the tone of blood vessels, mainly skin, kidneys and brain. Providing a relaxing effect on the venous walls in the pulmonary circulation, the drug reduces the pressure in it.
The use of Euphyllin improves the blood supply to the kidneys, thereby increasing the formation and excretion of urine.
The drug slows down platelet aggregation and makes erythrocytes more resistant to damage, that is, improves the rheological properties of blood.
It is known about the tocolytic effect of Euphyllin on the uterus, it also increases the acidity of gastric juice.
The agent is well absorbed from the digestive tract, its bioavailability reaches 100%. When taken simultaneously with food, absorption slows down somewhat. It passes into breast milk and through the placenta. Euphyllin's metabolism occurs in the liver, its excretion from the body occurs in the urine.
Release form
According to the instructions, Euphyllin is released in tablets of 150 mg, in ampoules in the form of a 2.4% and 24% solution.
Indications
The drug is used to relieve attacks of bronchial asthma, heart failure, angina pectoris, pulmonary edema and other conditions associated with congestion. According to reviews, Euphyllin effectively reduces blood pressure in hypertensive crises. It is used in the complex therapy of stroke and other ischemic conditions of the brain, in the treatment of apnea in newborns.
Contraindications
The use of Euphyllin is contraindicated in case of its intolerance, in the acute period of myocardial infarction, in case of collapse, paroxysmal tachycardia, extrasystole, epilepsy, hyperthyroidism, peptic ulcer, abnormalities in the functioning of the liver and kidneys, with prostate adenoma, diarrhea. It is not recommended to use the drug in tablets under the age of 6 years.
Instructions for the use of Euphyllin
In the form of a solution, the drug is administered intravenously and intramuscularly, parenteral use is justified in the treatment of emergency and urgent conditions. In this case, the dosage is calculated individually, depending on the severity of the condition and the patient's weight.
For adults in emergency situations, the dose of Euphyllin according to the instructions is selected at the rate of 6 mg / kg, it is diluted in 20 ml of saline sodium chloride solution, and injected intravenously slowly for at least 5 minutes.
Status asthmaticus requires infusion of the drug in the amount of 720 - 750 mg. Parenteral administration of Euphyllin is not recommended for longer than 14 days.
To alleviate the condition in chronic obstructive pulmonary diseases in the acute phase, start with a dose of 5-6 mg / kg of the drug. If necessary, it should be increased very carefully, under the control of its content in the blood.
In tablets, Euphyllin is taken 0.15 g from 1 to 3 times a day, after meals. The course of admission can last from several days to several months.
With apnea of newborns, when respiratory arrest lasts from 15 seconds with a simultaneous decrease in heart rate, the initial dose of this drug for newborns is 5 mg / kg / day in 2 divided doses. The drug is administered via a nasogastric tube. When the condition stabilizes, they switch to a maintenance dose of 2 mg / kg / day in 2 divided doses. The duration of use can range from several weeks to several months.
Depending on the severity of the condition and indications for Euphyllin in children, the daily dose varies from 6 to 15 mg / kg.
For elderly patients, care should be taken in drug treatment. According to reviews, Euphyllin enhances the side effects of glucocorticoids, mineralocorticoids and adrenostimulants. Do not use this agent simultaneously with other xanthine derivatives.
Side effects of Euphyllin
According to reviews, Euphyllin is capable of causing such undesirable effects as insomnia, dizziness, agitation, headaches, tremors, increased heart rate, arrhythmias, heart pain, lower blood pressure, abdominal pain, nausea, heartburn, vomiting, diarrhea, allergic reactions, increased sweating, decreased blood glucose, changes in urine tests.
Euphyllin: prices in online pharmacies
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Drug name Price Pharmacy |
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Euphyllin 150 mg tablets 30 pcs. RUB 10 Buy |
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Euphyllin 150 mg tablets 30 pcs. RUB 10 Buy |
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Euphyllin 150 mg tablets 30 pcs. 12 RUB Buy |
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Euphyllin 150 mg tablets 30 pcs. RUB 18 Buy |
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Euphyllin 24 mg / ml solution for intravenous administration 10 ml 10 pcs. RUB 25 Buy |
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Euphyllin 24 mg / ml solution for intravenous administration 5 ml 10 pcs. RUB 26 Buy |
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Euphyllin 24 mg / ml solution for intravenous administration 5 ml 10 pcs. RUB 29 Buy |
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Euphyllin 24 mg / ml solution for intravenous administration 5 ml 10 pcs. RUB 31 Buy |
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Euphyllin 24 mg / ml solution for intravenous administration 10 ml 10 pcs. RUB 40 Buy |
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Euphyllin 24 mg / ml solution for intravenous administration 5 ml 10 pcs. RUB 44 Buy |
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Euphyllin 24 mg / ml solution for intravenous administration 10 ml 10 pcs. RUB 49 Buy |
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Euphyllin 24 mg / ml solution for intravenous administration 10 ml 10 pcs. RUB 49 Buy |
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Euphyllin 24 mg / ml solution for intravenous administration 5 ml 10 pcs. RUB 50 Buy |
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Euphyllin solution for intravenous injection. 24mg / ml 5ml 10 pcs. RUB 66 Buy |
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Eufillin IV solution 24mg / ml amp. 10ml No. 10 89 RUB Buy |
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Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
