Ecofucin
Ekofucin: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Drug interactions
- 11. Analogs
- 12. Terms and conditions of storage
- 13. Terms of dispensing from pharmacies
- 14. Reviews
- 15. Price in pharmacies
Latin name: Ecofucin
ATX code: G01AA02
Active ingredient: natamycin (natamycin)
Producer: Farmea (France), AVVA-RUS, JSC (Russia)
Description and photo update: 06.06.2018
Prices in pharmacies: from 181 rubles.
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Ecofucin is an antifungal drug for topical use in gynecology.
Release form and composition
Dosage form Ekofutsin - vaginal suppositories: torpedo-shaped, from light brown to light yellow, with an acceptable air rod or funnel-shaped depression on the cut, without foreign inclusions (in a cell contour packaging 3 pcs., In a cardboard box 1 or 2 packages; in a blister contour packaging 6 pcs., in a cardboard box 1 package).
The composition of one suppository:
- active substance: natamycin (in terms of 100% substance) - 100 mg;
- auxiliary components: macrogol glyceryl hydroxystearate, lactulose, colloidal silicon dioxide, solid fat (Supposir AM).
Pharmacological properties
Pharmacodynamics
Natamycin, the active component of Ecofucin, is a polyene antibiotic from the macrolide group. It has a wide spectrum of antimycotic action. The fungicidal effect of natamycin is due to inhibition of the biosynthesis of sterols, which are components of cell membranes, as a result of which the integrity of fungal cells is disrupted, their growth and development stops.
Most pathogenic yeast-like fungi (especially Candida albicans), yeast (Rhodotorula and Torulopsis) and other pathogenic fungi (Penicillium, Aspergillus) are sensitive to natamycin. In relation to dermatophytes (Epidermophyton, Trichophyton, Microsporum), the drug is less active. It has no effect on gram-positive and gram-negative microorganisms in vitro.
Resistance to natamycin has not been observed in clinical practice.
Ecofucin contains the prebiotic lactulose as an excipient. This component helps to maintain the balance of the vaginal microflora and reduces the risk of developing vaginal dysbiosis.
Pharmacokinetics
Natamycin has no systemic effect, since when applied topically through intact skin and from the surface of mucous membranes, it is absorbed in small quantities.
Indications for use
According to the instructions, Ekofucin is indicated for use in candidiasis (caused by fungi of the genus Candida) vaginitis, vulvitis, vulvovaginitis.
Contraindications
A contraindication to the use of Ekofucin is an increased individual sensitivity to natamycin or any auxiliary component of the drug.
Instructions for the use of Ekofucin: method and dosage
Ecofucin suppositories are used intravaginally. Having previously freed the suppository from the contour packaging, it is inserted as deep as possible into the vagina, while in the supine position, immediately before bedtime.
The recommended dosing regimen for candidal vaginitis, vulvitis, vulvovaginitis: 1 suppository 1 time per day at night for 3-6 days.
In the case of persistent vaginitis caused by Candida albicans, natamycin is additionally prescribed in tablets for oral administration - 1 tablet 4 times a day for 10–20 days (to sanitize the focus of a fungal infection in the intestine).
The duration of the course of therapy is determined by the doctor. It is recommended to continue treatment for several days after the symptoms of the disease disappear.
During menstruation, suppositories are temporarily not used.
Side effects
With local application of Ekofucin, a burning sensation at the injection site and slight irritation are possible.
Overdose
At this time, there is no information on drug overdose.
special instructions
With intravaginal administration, suppositories under the influence of body temperature turn into a foamy substance, due to which natamycin is evenly distributed over the vaginal mucosa.
During treatment, there is no need to exclude sexual intercourse, but barrier methods of contraception should be used. It is recommended to examine the sexual partner for candidal infection and, if necessary, prescribe a course of therapy with natamycin.
Application during pregnancy and lactation
During pregnancy and during breastfeeding, the use of Ekofucin is allowed if indicated and according to the recommended dosing regimen.
Drug interactions
The interaction of the drug with other drugs has not been studied.
Analogs
Ekofucin's analogues are: Natamycin, Pimafucin, Primafungin and others.
Terms and conditions of storage
Store in a place protected from light and moisture, at a temperature not exceeding 25 ° C.
Keep out of the reach of children.
Shelf life is 2 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Ekofucin
According to reviews about Ekofucin, the drug is easy to use and does not cause almost any negative sensations. Suppositories in the first days of use eliminate itching, soreness, unpleasant odor and other symptoms of a fungal infection.
In addition, the drug has a relatively low cost.
The price of Ecofucin in pharmacies
The price of Ekofucin is approximately: 3 pcs. in the package - 200 rubles, 6 pcs. in the package - 400 rubles.
Ekofucin: prices in online pharmacies
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Drug name Price Pharmacy |
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Ekofucin 100 mg, vaginal suppositories 3 pcs. RUB 181 Buy |
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Ekofucin vaginal suppositories 100mg 3pcs 205 RUB Buy |
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Ekofucin 100 mg vaginal suppositories 6 pcs. 339 r Buy |
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Ecofucin vaginal suppositories. 100mg 6 pcs. 413 r Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
