Hondroguard
Hondrogard: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews
- 16. Price in pharmacies
Latin name: Chondrogard
ATX code: M01AX25
Active ingredient: chondroitin sodium sulfate (chondroitin sulfate sodium)
Producer: CJSC "PharmFirma" Sotex "(Russia)
Description and photo updated: 20.11.2018
Prices in pharmacies: from 679 rubles.
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Chondroguard is a remedy that stimulates the regeneration of cartilage tissue.
Release form and composition
Dosage form of Chondroguard - solution for intramuscular administration: with a slight yellowish tinge or colorless, transparent, with a characteristic smell of phenylcarbinol (in 1 ml ampoules of colorless glass, 5 ampoules in a cell contour package, 1 or 2 packages in a cardboard box; in ampoules from colorless glass, 2 ml, in a blister contour package 5 ampoules, in a cardboard box 1, 2 or 5 packages; in sterile glass syringes with or without a needle, 1 or 2 ml each, in a blister contour packaging 1 or 2 syringes, in a cardboard box 5 packs with or without a set of needles).
Composition of 1 ml solution:
- active substance: chondroitin sodium sulfate - 100 mg;
- auxiliary components: phenylcarbinol, sodium metabisulfite, sodium hydroxide, water for injection.
Pharmacological properties
Pharmacodynamics
The active ingredient of Chondroguard, chondroitin sodium sulfate, is a high molecular weight mucopolysaccharide that has a positive effect on metabolic metabolic processes in hyaline cartilage. It helps to reduce degenerative changes in the cartilage tissue of the joints, to accelerate the processes of its restoration, and stimulates the formation of proteoglycans. Thanks to chondroitin, phosphorus-calcium metabolism is restored, pain is reduced and the mobility of the affected joints improves. In the case of degenerative changes in the joints with secondary synovitis, treatment with the drug gives a positive effect already 2-3 weeks after the start of the course of therapy: pain syndrome decreases, the severity of clinical manifestations of reactive synovitis is significantly reduced, and the range of motion in diseased joints expands. After the end of the course of treatment with chondroitin, the therapeutic effect lasts for a long time.
Pharmacokinetics
Chondroitin sulfate is rapidly distributed after intramuscular injection. Already half an hour after administration, its significant concentration is observed in the blood. The maximum concentration (C max) of the substance in the blood plasma is reached after 1 hour, then gradually decreases within two days.
Chondroitin accumulates mainly in the cartilage tissue of the joints. The synovial membrane does not prevent the penetration of the substance into the joint cavity. Experiments have shown the presence of chondroitin sulfate in the synovial fluid 15 minutes after intravenous administration of the drug. Then the substance penetrates into the cartilaginous tissue and reaches C max there after 48 hours.
Indications for use
- degenerative-dystrophic lesions of the joints and spine: osteoarthritis of the peripheral joints, intervertebral osteoarthritis and osteochondrosis;
- fractures - to speed up the formation of callus.
Contraindications
- thrombophlebitis;
- bleeding and increased bleeding;
- pregnancy and lactation period;
- childhood;
- increased individual sensitivity to chondroitin or any of the auxiliary ingredients of the drug.
Instructions for the use of Hondrogard: method and dosage
Chondroguard solution is administered intramuscularly. The recommended starting dose is 100 mg every other day. Starting from the fourth injection, the dose is increased to 200 mg every other day, provided that the drug is well tolerated. The course of therapy includes 25-30 injections. If necessary, it is possible to repeat the course in 6 months.
To accelerate the formation of callus, the duration of the course of treatment is 3-4 weeks (10-14 injections every other day).
Side effects
During the use of Chondrogard, it is possible to develop allergic reactions in the form of itching, erythema, urticaria, dermatitis, as well as local reactions in the form of hemorrhage at the injection site.
Overdose
At this time, there is no information on an overdose of chondroitin.
special instructions
There are no special instructions for the use of the drug.
Application during pregnancy and lactation
Since there are no data on the safety of the use of Hondroguard during pregnancy and lactation, it is contraindicated to prescribe the drug to pregnant and lactating women.
Pediatric use
According to the instructions, Chondrogard is contraindicated for use in pediatrics.
Drug interactions
It is possible to enhance the effect of indirect anticoagulants, fibrinolytics and antiplatelet agents when used simultaneously with chondroitin sodium sulfate, as a result of which, in such cases, more frequent monitoring of blood clotting parameters is required.
Analogs
The analogues of Chondrogard are: Artogistan, Artravir-Inkampharm, Drastop, Mukosat, Chondroitin sulfate, Chondrolon and others.
Terms and conditions of storage
Store in a dark place at a temperature not exceeding 25 ° C.
Keep out of the reach of children.
The shelf life of the solution for intramuscular administration in ampoules is 3 years, in syringes - 2 years.
Terms of dispensing from pharmacies
Dispensed by prescription.
Reviews about Hondroguard
Reviews about Hondroguard are mostly positive. The drug helps many patients after the first injections - pain and inflammation decrease, and joint mobility increases. After the course of treatment, the therapeutic effect lasts, as a rule, for several months. There are practically no complaints about side effects.
Price for Hondroguard in pharmacies
The price of Hondroguard for a pack of 10 ampoules is approximately: in a dose of 1 ml - 840 rubles, 2 ml - 1500 rubles.
Hondroguard: prices in online pharmacies
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Drug name Price Pharmacy |
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Chondroguard 100 mg / ml solution for intramuscular administration 1 ml 10 pcs. RUB 679 Buy |
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Chondrogard solution for i / m and i / s entered 100mg / ml amp. 1ml 10 pcs. RUB 878 Buy |
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Chondroguard 100 mg / ml solution for intramuscular injection 2 ml 10 pcs. 1189 RUB Buy |
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Chondroguard solution for intramuscular and intravenous administration. 100mg / ml amp. 2ml 10 pcs. 1521 RUB Buy |
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Chondrogard 100 mg / ml solution for intramuscular injection 2 ml 25 pcs. 2125 RUB Buy |
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Chondrogard solution for i / m and i / s entered 100mg / ml amp. 2ml 25 pcs. 2898 RUB Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
