Zirtek - Instructions For Use, Indications, Doses, Analogues

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Zyrtec

Instructions for use:

1. 1. Release form and composition
2. 2. Indications for use
3. 3. Contraindications
4. 4. Method of application and dosage
5. 5. Side effects
6. 6. Special instructions
7. 7. Drug interactions
8. 8. Analogs
9. 9. Terms and conditions of storage
10. 10. Terms of dispensing from pharmacies

Prices in online pharmacies:

from 82 rub.

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Zyrtec is a blocker of histamine H ₁ receptors, an anti-allergic drug with antipruritic and anti-exudative action.

Release form and composition

• Film-coated tablets: oblong, biconvex, white, on one side there is a risk, on both sides of which there is an engraving "Y" (7 pcs. In blisters, in a cardboard box 1 blister; 10 pcs. In blisters, in a pack of cardboard 1 or 2 blisters);
• Drops for oral administration: transparent, colorless, with the smell of acetic acid (10 or 20 ml each in dark glass dropper bottles, in a cardboard box 1 bottle).

The active ingredient is cetirizine dihydrochloride:

• 1 tablet - 10 mg;
• 1 ml drops - 10 mg.

Excipients of tablets: colloidal silicon dioxide, lactose monohydrate, magnesium stearate, microcrystalline cellulose, Opadray Y-1-7000 (titanium dioxide (E171), hypromellose (E464), macrogol 400).

Excipients of drops: methylparabenzene, propylparabenzene, propylene glycol, sodium acetate, glycerol, glacial acetic acid, sodium saccharinate, purified water.

Indications for use

• Urticaria, including chronic idiopathic
• Pollinosis (hay fever);
• Quincke's edema;
• Seasonal and / or perennial rhinitis and conjunctivitis of allergic genesis (symptomatic treatment of symptoms such as itching, conjunctival hyperemia, lacrimation, sneezing, rhinorrhea);
• Other allergic dermatoses, accompanied by itching and rashes, including atopic dermatitis.

Contraindications

Absolute:

• End-stage renal failure (creatinine clearance less than 10 ml / minute);
• Lactase deficiency, hereditary galactose intolerance, glucose-galactose malabsorption syndrome;
• Children up to 6 months old - for drops, up to 6 years old - for tablets;
• Pregnancy and lactation;
• Increased individual sensitivity to the drug or hydroxyzine.

Relative:

• Chronic renal failure
• Chronic liver disease;
• Elderly age.

Method of administration and dosage

Zyrtec is taken orally.

Recommended doses:

• Adults: 10 mg (1 tablet or 20 drops) 1 time per day;
• Children over 6 years of age: 10 mg once a day or 5 mg (1/2 tablet or 10 drops) 2 times a day;
• Children 2-6 years old: 2.5 mg (5 drops) 2 times a day or 5 mg (10 drops) 1 time a day;
• Children 1-2 years old: 2.5 mg (5 drops) 1-2 times a day;
• Children 6-12 months: 2.5 mg (5 drops) 1 time per day.

In some cases, 5 mg per day is sufficient for adults and children over 6 years of age to achieve a therapeutic effect.

For elderly people and patients with renal insufficiency, the dose is adjusted depending on the creatinine clearance (CC), which is calculated as follows:

• For men: CC (ml / minute) = [140 - age (in years)] x body weight (in kilograms) / 72 x serum creatinine (mg / dl);
• For women: CC (ml / minute) = [140 - age (years)] x body weight (in kilograms) / 72 x serum creatinine (mg / dl) x 0.85.

Recommended doses of Zyrtek for patients with hepatic and renal impairment:

• CC 50-79 ml / minute (mild renal failure) - 10 mg / day;
• CC 30-49 ml / minute (average renal failure) - 5 mg / day;
• CC <30 ml / minute (severe renal failure) - 5 mg every other day.

In end-stage renal failure, the drug is contraindicated.

Patients diagnosed with only liver dysfunction do not need dose adjustment.

Side effects

Zyrtec is generally well tolerated, in rare cases the following side effects occur:

• Allergic reactions: rash, urticaria, itching, angioedema, hypersensitivity reactions, up to the development of anaphylactic shock;
• From the side of the organ of vision: blurred vision, violation of accommodation, nystagmus;
• From the side of metabolism: an increase in body weight;
• From the respiratory system: pharyngitis, rhinitis;
• From the side of the cardiovascular system: tachycardia;
• From the hematopoietic system: thrombocytopenia;
• From the urinary system: urinary disorder and enuresis;
• From the digestive system: nausea, dry mouth, diarrhea, abdominal pain, abnormal liver function (increased levels of hepatic transaminases, alkaline phosphatase, gamma-glutamyltransferase, bilirubin);
• From the nervous system: dizziness, drowsiness, headache, agitation, aggression, confusion, hallucinations, depression, insomnia, convulsions, tic, dyskinesia, paresthesia, dystonia, tremor, fainting;
• Others: fatigue, malaise, asthenia, edema.

special instructions

When taking Zyrtek at the recommended dose, no negative effect on the speed of reactions and the ability to concentrate was found. However, during treatment it is recommended to refrain from driving vehicles and performing potentially hazardous activities.

Drug interactions

No unwanted drug interactions of cetirizine with glipizide, erythromycin, ketoconazole, azithromycin, diazepam, cimetidine, pseudoephedrine were detected.

With the simultaneous use of theophylline (in a daily dose of 400 mg), the total clearance of cetirizine decreases by 16%, the kinetics of theophylline does not change.

Data on the interaction of Zirtek with alcohol have not been obtained, however, patients are advised to refrain from drinking alcoholic beverages during the period of drug treatment in order to avoid depression of the central nervous system.

Analogs

Zirtek's analogs are: Alercetin, Allertek, Amertil, Anallergin, Zodak, Parlazin, Rolinoz, Cetirizin Hexal, Cetirizin Sandoz, Cetirizin-Astrafarm, Cetirizin-Akrikhin, Cetirizin-Norton, Cetirizin, Ethylsilane, Cetrizinus, Cetirizin …

Terms and conditions of storage

Keep out of reach of children at a temperature: tablets - up to 30 ºС, drops - up to 25 ºС.

The shelf life is 5 years.

Terms of dispensing from pharmacies

Available without a prescription.

Zyrtec: prices in online pharmacies

Drug name Price Pharmacy

Zyrtec 10 mg film-coated tablets 7 pcs. 82 RUB Buy

Zyrtec 10 mg / ml drops for oral administration 10 ml 1 pc. RUB 87 Buy

Zyrtec drops for internal approx. 1% 10ml 89 RUB Buy

Zyrtec drops d / vn. reception 10mg / ml vial-dropper 20ml 192 RUB Buy

Zyrtec 10 mg film-coated tablets 20 pcs. 193 r Buy

Zyrtec tablets p.p. 10mg 20 pcs. 195 RUB Buy

Zyrtec tab. p / o captivity. 10mg No. 30 RUB 290 Buy

Zyrtec drops for internal approx. 10mg / ml drip vial 10ml RUB 319 Buy

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Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!