Calm formula Evalar
Calm formula Evalar: instructions for use and reviews
- 1.production and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. In case of impaired renal function
- 12. Drug interactions
- 13. Analogs
- 14. Terms and conditions of storage
- 15. Terms of dispensing from pharmacies
- 16. Reviews
- 17. Price in pharmacies
Latin name: Formula spokoystviya
ATX code: N05C
Active ingredient: motherwort herb (Motherwort herb) + magnesium asparaginate (Magnesium asparaginate) + pyridoxine (vitamin B6) [Pyridoxine (Vitamin B6)]
Manufacturer: FC "Evalar" (Russia)
Description and photo update: 2019-08-07
Calm Formula Evalar is a sedative drug.
Release form and composition
The product is available in the form of film-coated tablets: white or almost white, round, biconvex; the core is white with a brown or gray tint and numerous dark blotches (20 pcs. in blisters, in a cardboard box 1, 2 or 3 packs and instructions for using the Evalar Calm Formula).
Composition of 1 film-coated tablet:
- active ingredients: motherwort dry extract - 50 mg (the sum of flavonoids in terms of rutin - 1%), magnesium asparaginate tetrahydrate - 250 mg (equivalent to 17 mg of magnesium ions), vitamin B 6 (pyridoxine hydrochloride) - 1 mg;
- auxiliary components: potato starch, microcrystalline cellulose, colloidal silicon dioxide, croscarmellose sodium, maltodextrin, calcium stearate;
- shell: polyethylene glycol 4000 (macrogol-4000), titanium dioxide, hydroxypropyl methylcellulose (hypromellose), talc.
Pharmacological properties
Pharmacodynamics
Calm formula Evalar is a complex sedative drug that has an anti-anxiety, anti-stress effect. Improving the tolerance of psychoemotional stress, it does not make the patient sleepy, lethargic or addictive.
The pharmacological effect of the drug on the nervous system is due to the following properties of its active components:
- motherwort extract: has a sedative, slight cardiotonic and hypotensive effect. A moderate cardiotonic effect is manifested by a slowdown in rhythm and an increase in heart rate, which helps a person to overcome stress. At the same time, there is a mild decrease in blood pressure, which rose against the background of stress and anxiety;
- magnesium: magnesium ions are found in all cells and tissues of the body and are involved in most biochemical reactions, including protein synthesis. Magnesium is one of the essential trace elements necessary for the normal functioning of the cardiovascular and digestive systems. Due to its active participation in the neuromuscular transmission of impulses, it plays an important role in the functioning of the nervous system. A manifestation of magnesium deficiency in the human body can be a violation of the heart rhythm (tachycardia, extrasystole), neuromuscular disorders (including muscle weakness, spasms, convulsions, tremors), mental disorders in the form of irritability, insomnia, anxiety;
- pyridoxine hydrochloride: Vitamin B 6 is essential for faster and more complete absorption of magnesium. Plays an important role in the normal functioning of the central and peripheral nervous system, metabolism and hematopoiesis, influencing erythropoiesis.
Pharmacokinetics
The combined composition of the Evalar Calm Formula does not allow tracing the pharmacokinetics of its individual components.
Indications for use
- neurosis-like and neurotic reactions, which are accompanied by irritability, increased nervous excitability, anxiety, fear;
- insomnia, manifested by such sleep disorders as sleep disturbance, intermittent shallow sleep, premature awakening;
- neurocirculatory dystonia (as part of complex therapy).
Contraindications
Absolute:
- acute period of gastric ulcer and duodenal ulcer;
- phenylketonuria;
- severe renal failure with creatinine clearance (CC) less than 30 ml / min;
- period of pregnancy;
- breast-feeding;
- age up to 18 years;
- individual intolerance to the components of the drug.
The Evalar Calm Formula should be used with caution and only as directed by the attending physician for arterial hypotension, bradycardia, and moderate renal failure.
Calm formula Evalar, instructions for use: method and dosage
Evalar Calm Formula tablets are taken orally with meals.
Recommended dosage:
- neurotic and neurosis-like reactions, neurocirculatory dystonia: 1 pc. 2 times a day;
- sleep disorders: 1 pc. 0.5 hours before going to bed.
The duration of the course of treatment should be determined by the doctor, taking into account the course of the disease, usually it is up to 28 days.
You can repeat the course of treatment on the recommendation of a doctor.
Side effects
- on the part of the immune system: possibly - allergic reactions;
- from the gastrointestinal tract: possibly - dyspepsia (including heartburn, abdominal pain, flatulence, nausea, diarrhea or constipation).
Overdose
Symptoms: possibly - spastic pain in the abdomen, a feeling of fatigue, hand tremors, dizziness.
Treatment: immediate gastric lavage, seeking medical attention.
special instructions
It is recommended to start using the Evalar Calm Formula after prior consultation with your doctor.
If symptoms of the development of undesirable phenomena occur, taking the tablets should be stopped immediately and consult a doctor.
Taking the drug in patients with functional impairment of the kidneys must be accompanied by monitoring the level of magnesium concentration in the blood serum.
Influence on the ability to drive vehicles and complex mechanisms
During the period of taking the tablets, patients should be careful when driving vehicles, working with moving mechanisms and performing other potentially hazardous activities that require increased attention and high speed of psychomotor reactions.
Application during pregnancy and lactation
It is not recommended to take tablets during gestation and lactation, this is due to the lack of sufficient experience in the clinical application of the Evalar Calm Formula in this category of patients.
Pediatric use
Due to the lack of clinical research results on the efficacy and safety of the Evalar Calm Formula for the treatment of children and adolescents, it is contraindicated to take tablets under the age of 18 years.
With impaired renal function
It is contraindicated to use the Evalar Calm Formula in severe renal failure (CC less than 30 ml / min).
Caution should be exercised in case of moderate renal impairment and take pills only as directed by a doctor.
Drug interactions
- hypotensive, hypnotics and other drugs that depress the central nervous system: their effect is enhanced;
- phosphorus and calcium preparations: concomitant therapy with drugs containing calcium salts and phosphates can cause a significant decrease in absorption of magnesium in the gastrointestinal tract;
- tetracycline: a decrease in its absorption is possible, due to the presence of magnesium in the preparation (it is recommended to take the Evalar Calm Formula after taking an antibiotic, observing an interval of at least three hours);
- thrombolytic agents for oral administration: their activity may be weakened;
- iron supplements: iron absorption decreases;
- levodopa: there is a decrease in its activity due to the presence of pyridoxine hydrochloride in the preparation.
Analogs
The analogues of the Evalar Calm Formula are: Motherwort tincture, Hawthorn tincture, Valerian, Validol, Corvalol, Corvaldin, Piona tincture, Alora, Bioson, Antistress, Belisa, Valokormid, Valemidin, Sonafit, Valdispert, Barboval, Dono-Passen and …
Terms and conditions of storage
Keep out of the reach of children.
Store at temperatures up to 25 ° C.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews of the Evalar Calm Formula
Reviews of the Evalar Calm Formula are few, but they are positive.
Price for Evalar Calm Formula in pharmacies
The price of Evalar Calm Formula for a package containing 40 tablets can range from 209 rubles.
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
