Portalak
Portalak: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews
- 16. Price in pharmacies
Latin name: Portalak
ATX code: A06AD11
Active ingredient: lactulose (Lactulose)
Manufacturer: BELUPO, medicines and cosmetics dd (BELUPO, Pharmaceuticals & Cosmetics, dd) (Croatia)
Description and photo update: 2019-28-11
Prices in pharmacies: from 241 rubles.
Buy
Portalak is a laxative that stimulates intestinal motility.
Release form and composition
The drug is produced in the form of a syrup: a viscous transparent liquid from colorless to brown-yellow colored (200, 250, 480, 500 and 1000 ml in polyethylene bottles, in a cardboard box 1 bottle complete with a measuring cup and instructions for using Portalak) …
100 ml of syrup contains:
- active substance: lactulose concentrate - 66.7 g;
- auxiliary component: purified water.
Pharmacological properties
Pharmacodynamics
Portalac is a laxative with a hyperosmotic effect. Its mechanism of action is due to the influence of lactulose on the potentiation of the reproduction process in the intestine of Lactobacillus acidophilus and Lactobacillus bifidus, which causes a decrease in acidity in the lumen of the large intestine and the activation of its peristalsis. Along with the stimulation of intestinal motility, lactulose improves the absorption of phosphates and calcium salts, excretion of ammonium ions, and slows down the growth of Salmonella in the large intestine. Against the background of taking Portalak, the volume of feces increases and their softening occurs. The syrup does not directly affect the mucous membrane and smooth muscles of the large intestine.
The effect of lactulose helps to reduce the formation of nitrogen-containing toxic substances in the proximal colon and their absorption into the systemic circulation. The level of ammonium ions in the blood decreases by 25-50%, the severity of hepatic encephalopathy decreases, the patient's mental state improves and electroencephalography is normalized.
After taking the syrup inside, the therapeutic effect occurs as the drug passes through the gastrointestinal tract (GIT) for 24-48 hours.
Pharmacokinetics
After oral administration, lactulose is practically not absorbed from the gastrointestinal tract, no more than 3% of the dose taken is absorbed.
While taking vitamins, their absorption is not reduced.
Portalak is not addictive.
Due to the insignificant systemic effect of lactulose for elderly patients, with renal or hepatic insufficiency, dosage adjustment is not required.
Indications for use
- constipation, including chronic constipation;
- intestinal dysbiosis;
- hemorrhoids, pain syndrome after removal of hemorrhoids, preparation for surgery on the colon and / or anus, postoperative period - in order to soften the stool for medical purposes;
- hyperammonemia;
- hepatic encephalopathy;
- treatment and prevention of hepatic precoma and coma;
- enteritis due to salmonella or shigella;
- salmonella carriage;
- putrid dyspepsia syndrome in young children due to acute food poisoning.
Contraindications
Absolute:
- intestinal obstruction;
- galactosemia;
- rectal bleeding not associated with hemorrhoids;
- colostomy, ileostomy;
- suspicion of appendicitis;
- individual intolerance to lactulose.
Patients with lactose intolerance, diabetes mellitus, gastrocardiac syndrome should be used with caution.
Portalak, instructions for use: method and dosage
Portalac syrup is taken orally, preferably during or after a meal, with water or other liquid.
The dose of the drug should be selected individually. The dose or time of administration should be changed as needed.
After the start of taking the laxative effect develops during the first two days of therapy.
Recommended dosage of Portalak:
- treatment of constipation and softening of stools: infants under 1 year old - 5 ml (1 teaspoon) per day; children aged 1-6 years - 5-10 ml per day; children from 7 to 14 years old, initial dose (3 days) - 15 ml (1 tablespoon) per day, maintenance dose - 10 ml per day; adults, the initial dose is 15–45 ml per day for three days, then 15–30 ml per day. The daily dose is taken once in the morning or divided into two doses. In the treatment of constipation, the duration of the course can be from 28 to 120 days;
- treatment of hepatic (portal) encephalopathy, hepatic coma and precoma: 30-50 ml 3 times a day. In order to achieve a quick effect, the initial dose can be 30–45 ml with an interval of 1–2 hours. After the first emptying of the intestine, the patient is transferred to a supporting individual dose that provides soft stools 2–3 times a day;
- treatment of dysbiosis, normalization of intestinal microflora: a single dose for children under 1 year old - 1.5-3 ml, from 1 to 3 years old - 3 ml, from 3 to 7 years old - 5 ml, for adults and children over 7 years old - 5– 10 ml. It is divided into 2-4 doses per day during or after meals. The duration of the course of treatment is 10-14 days. Repeated courses are prescribed with an interval of 7 days.
Side effects
Adverse events against the background of the use of Portalak arise, as a rule, due to an excess of the dose and are mildly reversible. Reducing the dose may be sufficient to relieve abdominal discomfort or pain, cramps and diarrhea.
The flatulence that appears at the beginning of treatment usually resolves in 1–2 days.
Skin reactions in the form of a rash are possible.
Long-term use of high doses of lactulose in the treatment of hepatic encephalopathy can cause imbalance in the water-electrolyte balance in patients, which results in weakness, increased fatigue, nausea, headache, dizziness, convulsions, arrhythmias, myalgia.
Overdose
Symptoms of an overdose of lactulose are diarrhea, imbalance in water and electrolyte balance.
For the purpose of treating the condition, you should immediately stop taking the laxative.
special instructions
If, after several days of taking Portalak, the constipation persists or if constipation recurs after discontinuation of the drug, consult your doctor.
Patients with lactose intolerance and diabetes mellitus should take into account that 15 ml of syrup contains up to 1.7 g of galactose and up to 1 g of lactose.
Treatment of patients with gastrocardial syndrome should be started with lower doses, then gradually increased, this will minimize the risk of flatulence.
In the treatment of hepatic encephalopathy, other laxatives should not be used simultaneously, especially in the initial phase of therapy. Intense bowel movements may erroneously indicate the achievement of an adequate dose for the treatment of encephalopathy.
Influence on the ability to drive vehicles and complex mechanisms
The use of the recommended doses of lactulose does not affect the ability of patients to drive vehicles and complex mechanisms.
Application during pregnancy and lactation
According to clinical indications, the use of Portalak is allowed during pregnancy and breastfeeding.
Pediatric use
The use of Portalak syrup in children of any age (from birth) is shown in accordance with the recommended dosage regimen.
Drug interactions
For the first two hours after taking any other medicine, it is recommended to refrain from taking Portalac.
When taken simultaneously with drugs containing mesalazine, it should be borne in mind that the environment created by lactulose in the large intestine can contribute to their inactivation.
With concomitant therapy with antibiotics (including neomycin) and antacids, the clinical effect of Portalac is reduced.
Analogs
Analogues of Portalak are Goodluck, Duphalac, Lactulose, Lactulose Canon, Lactulose Stada, Lactulose-Teva, Livolyuk-PB, Normase, Prelax, Romfalak, Evict, etc.
Terms and conditions of storage
Keep out of the reach of children.
Store at temperatures up to 25 ° C, keep away from freezing.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Portalak
Reviews about Portalak are positive. Patients indicate the high efficacy of the drug in the treatment of constipation. It is especially noted that the laxative is approved for use by both adults and children (including infants and the elderly), as well as pregnant and breastfeeding women. In addition, the advantages include a safe composition, pleasant taste, mild action, lack of addiction and the possibility of long-term use, good tolerance of Portalak.
Price for Portalak in pharmacies
The price of Portalak for a package containing 1 bottle of syrup 250 ml can be from 216 rubles, 500 ml - from 315 rubles.
Portalak: prices in online pharmacies
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Drug name Price Pharmacy |
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Portalak 66.7% syrup 250 ml 1 pc. 241 RUB Buy |
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Portalak 66.7% syrup 500 ml 1 pc. 336 r Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
