Lomilan - Instructions For Use, Tablets, Syrup, Reviews, Price

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Lomilan

Lomilan: instructions for use and reviews

1. 1. Release form and composition
2. 2. Pharmacological properties
3. 3. Indications for use
4. 4. Contraindications
5. 5. Method of application and dosage
6. 6. Side effects
7. 7. Overdose
8. 8. Special instructions
9. 9. Application during pregnancy and lactation
10. 10. Use in childhood
11. 11. In case of impaired renal function
12. 12. For violations of liver function
13. 13. Drug interactions
14. 14. Analogs
15. 15. Terms and conditions of storage
16. 16. Terms of dispensing from pharmacies
17. 17. Reviews
18. 18. Price in pharmacies

Latin name: Lomilan

ATX code: R06AX13

Active ingredient: loratadine (loratadine)

Manufacturer: LEK dd (Slovenia)

Description and photo updated: 28.08.

Prices in pharmacies: from 62 rubles.

Buy

Lomilan is an antihistamine drug of systemic action, blocker of H ₁ -histamine receptors. It has antiallergic, antipruritic, antiexudative effect.

Release form and composition

• Tablets: flat, round, with a chamfer, on one side there is a dividing line, almost white or white (10 pcs. In a blister, in a cardboard box 1, 2 or 3 blisters; 7 pcs. In a blister, in a cardboard box 1 blister);
• Suspension for oral administration: homogeneous suspension from almost white to white color (120 ml in dark glass vials, in a cardboard box 1 vial complete with a dosage spoon).

Each pack also contains instructions for the use of Lomilan.

Composition of 1 tablet:

• Active ingredient: loratadine - 10 mg;
• Additional components: gelatinized starch, corn starch, magnesium stearate, lactose.

Composition of 1 ml of oral suspension:

• Active ingredient: loratadine - 1 mg;
• Additional components: citric acid monohydrate, polysorbate 80, sodium benzoate, sodium citrate dihydrate, crystal white sugar, Avicel RC 591 FMC, concentrated glycerol, propylene glycol, wild cherry aroma, purified water.

Pharmacological properties

Pharmacodynamics

Loratadine - the active substance of the suspension and tablets Lomilan - is a blocker of histamine H ₁ receptors for systemic use. It has anti-allergic, antipruritic and anti-exudative properties.

It does not affect the central nervous system, does not cause addiction.

Lomilan helps to reduce capillary permeability, prevents tissue edema, relieves spasms of smooth muscles.

The development of the therapeutic effect begins 30 minutes after ingestion, the maximum effect is observed after 8-12 hours and lasts for 24 hours.

Pharmacokinetics

After oral administration, the substance is rapidly and completely absorbed from the gastrointestinal tract. After a single dose of 10 mg of loratadine, C _max (maximum concentration of the substance) is reached in 60 minutes. In the presence of food, absorption is slowed down.

Plasma protein binding is more than 95%. It does not penetrate the blood-brain barrier.

Metabolism occurs in the liver, with the formation of an active metabolite - descarboethoxyloratadine.

T _1/2 (half-life) is approximately 8 hours. It is excreted in urine and bile.

In chronic alcoholism and in the elderly, T _1/2 increases.

The pharmacokinetic parameters of loratadine during hemodialysis and in chronic renal failure practically do not change.

Indications for use

Lomilan tablets and syrup are used for the treatment and prevention of the following diseases / conditions:

• Year-round and seasonal allergic inflammation of the nasal mucosa (rhinitis);
• Allergic inflammation of the mucous membrane of the eye (conjunctivitis);
• Allergic skin diseases (including chronic idiopathic urticaria);
• Pseudo-allergic reactions;
• Allergy to insect bites.

Contraindications

Absolute:

• lactose intolerance, lactase deficiency, glucose-galactose malabsorption (tablets);
• fructose intolerance, sucrase / isomaltase deficiency, glucose-galactose malabsorption (suspension);
• pregnancy and lactation;
• age up to 2 or 3 years (suspension and tablets, respectively);
• individual intolerance to the components of the drug.

Relative (Lomilan is prescribed under medical supervision):

• severe renal failure (in patients with creatinine clearance <30 ml / min);
• liver failure.

Lomilan, instructions for use: method and dosage

The drug is taken orally with milk or water. Allowed to be taken simultaneously with food. Lomilan tablets can be chewed if necessary.

Dosing regimen:

• tablets: adult patients and children over 12 years old - 1 pc. (10 mg) 1 time per day, children from 3 to 12 years old, whose body weight exceeds 30 kg - 1 pc. (10 mg) 1 time per day, children over 3 years old with body weight less than 30 kg - ½ pc. (5 mg) once a day;
• oral suspension: adult patients and children over 12 years old - 2 dosage spoons (10 ml) once a day, children from 2 to 12 years old, whose body weight exceeds 30 kg - 2 dosage spoons (10 ml) once a day, children over 2 years old with a body weight of less than 30 kg - 1 dosage spoon (5 ml) 1 time per day.

For children under the age of 12, it is preferable to take Lomilan syrup.

Patients with impaired hepatic function should reduce the daily dose of the drug, appointing adults and children weighing more than 30 kg 2 dosage spoons of suspension (10 ml) or 1 tablet (10 mg) every other day. The duration of treatment depends on the duration of the symptoms of the disease.

In patients with severe renal impairment (CC <30 ml / min), the starting dose is: adults and children from 6 years of age - 2 dosage spoons of suspension (10 ml) or 1 tablet (10 mg) every other day, children from 3 to 6 years - 1 dosage spoon of suspension (5 ml) or ½ tablet (5 mg) every other day.

Patients with moderate and mild renal impairment, as well as elderly patients, do not require dose adjustment of Lomilan.

In the absence of improvement within 3 days of therapy, it is necessary to resolve the issue of the effectiveness of the drug with the attending physician.

Side effects

The frequency of the noted adverse reactions when using Lomilan was the same as when taking placebo and depended on the age category of patients:

• Children: rarely - nervousness, headache, sedation;
• Adults: dry mouth, headache, drowsiness, nausea, gastritis, increased fatigue; rarely - alopecia, allergic skin rashes, anaphylactic reactions, liver dysfunction.

Overdose

Overdose symptoms are: drowsiness, headache, palpitations (may last for a long period). For the purpose of therapy, it is necessary to remove the drug from the gastrointestinal tract as quickly as possible, and, if possible, reduce its absorption (activated carbon, gastric lavage). There is no specific antidote for loratadine today.

special instructions

Two days before the allergic skin tests, the intake of Lomilan must be stopped, since it can distort the test results.

Influence on the ability to drive vehicles and complex mechanisms

There is no data on the effect of Lomilan (when used in recommended doses) on concentration and psychomotor speed. However, patients need to be careful if the dose is exceeded or if unusual reactions occur while engaging in potentially hazardous activities.

Application during pregnancy and lactation

Lomilan is not prescribed during pregnancy / lactation.

Pediatric use

Contraindication:

• suspension: up to 2 years;
• tablets: up to 3 years.

With impaired renal function

In patients with severe renal impairment (with creatinine clearance <30 ml / min) Lomilan is prescribed with caution.

For violations of liver function

In case of liver failure, Lomilan should be used under medical supervision.

Drug interactions

• Ketoconazole and cimetidine - increase the concentration of loratadine in the blood;
• Microsomal oxidation inducers (ethanol, rifampicin, phenytoin, barbiturates, tricyclic antidepressants) - reduce the effectiveness of loratadine.

Analogs

Lomilan's analogs are: Loratadin, Loratadin Teva, Loratadin-Akrikhin, Lorahexal, Loridin.

Terms and conditions of storage

Store out of the reach of children, at temperatures up to 25 ° C, protect the tablets from light and moisture.

The shelf life of the suspension and tablets is 4 years.

Terms of dispensing from pharmacies

Available without a prescription.

Reviews about Lomilan

Reviews about Lomilan are mostly positive. Patients report its high efficiency in the treatment of allergic diseases in both adults and children. The cost is assessed as affordable. There is practically no information about the development of side reactions in the form of drowsiness.

The price of Lomilan in pharmacies

The approximate price for Lomilan is: tablets - 117-127 rubles. (7 pcs in the package) or 130-143 rubles. (10 pcs in a package), suspension - 86–98 rubles. (1 bottle of 120 ml).

Lomilan: prices in online pharmacies

Drug name Price Pharmacy

Lomilan 10 mg tablets 7 pcs. RUB 62 Buy

Lomilan 10mg tablets 7 pcs. RUB 111 Buy

Lomilan 10 mg tablets 10 pcs. 118 RUB Buy

Lomilan 10mg tablets 10 pcs. 129 RUB Buy

Anna Kozlova Medical journalist About the author

Education: Rostov State Medical University, specialty "General Medicine".

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!