Levomycetin
Instructions for use:
- 1. Pharmacological action
- 2. Release form
- 3. Indications for use
- 4. Contraindications
- 5. Instructions for use
- 6. Description of side effects and reviews
- 7. Storage conditions
Prices in online pharmacies:
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Levomycetin is an antibacterial drug used to treat infectious diseases. It is widely used in ophthalmology and pediatrics.
pharmachologic effect
Levomycetin is a broad-spectrum antibiotic.
The active substance of Levomycetin effectively affects many gram-positive and gram-negative bacteria, as well as pathogens of meningococcal infection, purulent infections, dysentery, typhoid fever.
Levomycetin is indicated in the treatment of diseases caused by hemophilic bacteria, chlamydia, rickettsia, brucella, spirochetes. In therapeutic concentrations, Levomycetin has a bacteriostatic effect.
Levomycetin, according to the instructions, is weakly active against Pseudomonas aeruginosa, acid-fast bacteria, clostridia and protozoa. Drug resistance to Levomycetin develops relatively slowly, but cross-resistance to other chemotherapeutic drugs usually does not occur.
With local application of Levomycetin, the therapeutic concentration is created in the iris, cornea, vitreous humor, aqueous humor, while Levomycetin does not penetrate into the lens.
Levomycetin, according to the instructions, is rapidly and well absorbed both after oral administration and with rectal administration, reaching a maximum concentration in the blood after a few hours.
Penetrating into organs, fluids and tissues of the body, Levomycetin penetrates well into the cerebrospinal fluid, as well as into breast milk.
Release form
Levomycetin is released in the form:
- Yellowish round tablets of Levomycetin containing 0.5 g and 0.25 g of the active substance of Levomycetin. Excipients - stearic acid or calcium stearic acid, potato starch;
- Powder for solution for injection. Each bottle contains 500 or 1000 mg of active ingredient;
- Eye drops (0.25% solution). 1 ml of the drug contains 2.5 mg of active ingredient. In dropper bottles of 5 and 10 ml.
Indications for the use of Levomycetin
Levomycetin is used for:
- Persiniosis;
- Generalized forms of salmonellosis;
- Paratyphoid;
- Tularemia;
- Rickettsioses;
- Brucellosis;
- Typhoid fever;
- Meningitis;
- Chlamydia.
For infectious diseases of a different etiology, which are caused by pathogens that are sensitive to the drug, Levomycetin is indicated when other chemotherapeutic agents are ineffective or in cases where their use is impossible due to individual intolerance.
In ophthalmology, Levomycetin is indicated for the prevention and treatment of infectious eye diseases:
- Blepharitis;
- Conjunctivitis;
- Keratitis.
Contraindications
According to the instructions, the use of Levomycetin is contraindicated in:
- Individual intolerance to the active substance;
- Various skin diseases, including psoriasis, fungal infections, eczema;
- Suppression of hematopoiesis.
Levomycetin according to the instructions is not used during pregnancy, in newborns, as well as during lactation.
Levomycetin for children and adults should not be prescribed for angina, acute respiratory diseases, as well as for prophylactic purposes and in milder forms of infectious processes.
Levomycetin cannot be administered simultaneously with:
- Sulfonamides;
- Diphenin;
- Butamide;
- Cytostatics;
- Pyrazolone derivatives;
- Neodicumarin;
- Barbiturates.
Instructions for the use of Levomycetin
In tablets, Levomycetin is used orally half an hour before meals.
Usually adults take 1-2 tablets of Levomycetin (0.25 g each) 3-4 times a day, but no more than 2 g of the drug per day. In severe cases, the maximum dose may be 4 g, divided into 3-4 doses, under strict control of liver and kidney function and blood condition.
A single dose of Levomycetin for children under 3 years old is calculated on the basis of weight - 10-15 mg per 1 kg, children 3-8 years old - 0.15-2 g, older children - 0.2-0.3 mg per 1 kg masses.
A single dose of Levomycetin is taken by children from 3 to 4 times a day, depending on the course of the disease.
The duration of the course of treatment with Levomycetin according to the instructions is 7-10 days, and in some cases, with good tolerability of the drug and the absence of side effects, up to two weeks.
A solution prepared from a powder is used for intravenous and intramuscular administration. For children, Levomycetin is prescribed only intramuscularly, for which the contents of the bottle are dissolved in 2-3 ml of water for injection. In case of diabetes mellitus for intravenous jet injection, the contents of the vial are dissolved in 10 ml of water for injection. Injections are carried out at regular intervals. The duration of the course of treatment with Levomycetin and the dose are determined individually.
Adults are usually prescribed 500-1000 mg of Levomycetin 2-3 times a day, and in severe infections, the dose can be doubled, but not more than 4000 mg per day.
In ophthalmology, the ready-made solution is used for instillations or parabulbar injections, instilling a few drops of 5% Levomycetin solution into the conjunctival sac from 3 to 5 times a day. The duration of the course is usually from 5 to 15 days.
Description of side effects of Levomycetin and reviews
According to the description and reviews, when using Levomycetin, various side effects may appear:
- Thrombocytopenia;
- Leukopenia;
- Reticulocytopenia;
- Allergic reactions manifested as skin rashes;
- Cytoplasmic vacuolization of early erythrocyte forms;
- Decrease in blood hemoglobin levels.
Usually these side effects are reversible and go away on their own after discontinuation of Levomycetin.
Also, according to the instructions and reviews, Levomycetin can cause:
- Confusion of consciousness;
- Decreased visual acuity and hearing;
- Psychomotor disorders;
- Visual and auditory hallucinations;
- Dyspeptic symptoms - vomiting, nausea, or loose stools.
When using Levomycetin in infants, in rare cases, cardiovascular collapse may develop.
Storage conditions
The shelf life of tablets is 3 years, powder for preparation of solution for injections is 4 years, eye drops is 2 years, while an opened bottle can be stored for no more than a month.
Levomycetin: prices in online pharmacies
Drug name Price Pharmacy |
Levomycetin (eye drops) 0.25% eye drops 5 ml 1 pc. RUB 4 Buy |
Levomycetin (eye drops) 0.25% eye drops 10 ml 1 pc. RUB 7 Buy |
Levomycetin (eye drops) 0.25% eye drops 10 ml 1 pc. RUB 7 Buy |
Levomycetin (eye drops) 0.25% eye drops 10 ml 1 pc. RUB 13 Buy |
Levomycetin eye drops 0.25% vial. 10ml RUB 15 Buy |
Levomycetin eye drops 0.25% 10ml RUB 15 Buy |
Levomycetin eye drops 0.25% 5ml RUB 15 Buy |
Levomycetin 250 mg tablets 10 pcs. 22 RUB Buy |
Levomycetin 500 mg tablets 10 pcs. RUB 36 Buy |
Levomycetin (eye drops) 0.25% eye drops 10 ml 1 pc. RUB 64 Buy |
Levomycetin Aktitab 500 mg film-coated tablets 10 pcs. 79 RUB Buy |
Reviews Levomycetin Aktitab 79 RUB Buy |
Levomycetin 500 mg tablets 20 pcs. RUB 81 Buy |
Levomycetin Aktitab tablets p.p. 500mg 10 pcs. 117 RUB Buy |
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Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!