Lipin

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Instructions for use:

1. Release form and composition
2. Indications for use
3. Contraindications
4. Method of application and dosage
5. Side effects
6. Special instructions
7. Drug interactions
8. Analogs
9. Terms and conditions of storage
10. Terms of dispensing from pharmacies

Lipin is a drug that affects metabolism and the digestive system.

Release form and composition

Lipin is produced in the form of a lyophilisate for the preparation of an emulsion: an amorphous mass of light yellow or white color with a characteristic odor (in bottles or vials of 100, 250 or 500 mg, 1 bottle or bottle in a cardboard box or 3 bottles in a cardboard box in a set with the NEBULISER inhaler).

The composition of 1 bottle (bottle) includes:

Active ingredient: lecithin - 100, 250 or 500 mg (in the form of standard lecithin);
Auxiliary component: lactose.

Indications for use

Lipin is prescribed as part of the complex treatment of the following diseases:

Cardiology: unstable angina pectoris and acute myocardial infarction;
Pulmonology: a syndrome of chronic and acute respiratory failure of any genesis in adults and children, including newborns with respiratory disorders associated with previous perinatal hypoxia and asphyxia during childbirth;
Obstetrics: intra-abdominal fetal hypoxia, late gestosis;
Gastroenterology: active hepatitis (acute and chronic), cirrhosis of the liver, chronic non-calculous cholecystitis, ulcerative colitis;
Nephrology: polycystic disease, acute and chronic pyelonephritis, diabetic nephropathy, glomerulonephritis, renal failure.

Contraindications

Lipin is contraindicated for use in the presence of hypersensitivity to the components of the drug.

The lyophilisate contains lactose, therefore, patients with rare hereditary forms of galactose intolerance, glucose-galactose malabsorption syndrome or lactase deficiency should not use the drug.

Method of administration and dosage

Lipin is used orally, intravenously, rectally and by inhalation.

The liposomal emulsion should be prepared immediately before use. For this, the bottle (vial) is kept for 30 minutes at room temperature. To prepare an emulsion for intravenous administration, a 0.9% sodium chloride solution for injection or infusion, preheated to 36 ° C, is added to it in a ratio of 10: 1 (10 ml of solution per 100 mg of lyophilisate). When preparing an emulsion for inhalation, a ratio of 100: 2 is used (for 100 mg of lyophilisate - 2 ml of solution). Then the bottle should be shaken until a homogeneous white emulsion is formed (about 2 minutes).

When preparing an emulsion for rectal use and ingestion, boiled or distilled water can be used.

Lipin should not be used in the same syringe or inhalation device with other inhalation or parenteral solutions.

Pulmonology:

When used by inhalation, usually 10-15 mg / kg of body weight is prescribed for 1 inhalation. Frequency rate of application - 1-2 times a day (in severe cases - 3 times a day), course duration - 5-10 days.

For newborns with respiratory distress syndrome, the drug is prescribed 3-4 times a day at doses of 25-100 mg / kg of body weight. The optimal duration of inhalation is 3-4 minutes, the duration of the course is 4-5 days (if necessary, it can be extended to 10-12 days).

It is possible to connect the inhaler to the respiratory circuit of the ventilator (artificial lung ventilation). When carrying out inhalation, you need to use aerosol-type inhalers or ultrasonic inhalers. The use of steam aerosol inhalers is unacceptable.

Obstetrics:

With gestosis, Lipin is administered intravenously slowly.

The duration of the course is determined by clinical manifestations and can vary from 3 to 10 days.

Gastroenterology:

For acute or chronic active hepatitis, chronic non-calculous cholecystitis and liver cirrhosis Lipin is taken orally 2 times a day, 1000 mg. The duration of the course is 18-21 days. In severe disease, the lyophilisate is dissolved in a 5% glucose solution and injected intravenously at the same dose. The duration of the course is 10 days. In the course of therapy, it is possible to change the method of Lipin administration.

In the treatment of ulcerative colitis, the drug is used in the form of microclysters in a single dose:

1-10 days: 1000 mg;
11-20 days: 500 mg.

Frequency rate of application - 2 times a day, course duration - 20 days.

Nephrology:

In the treatment of chronic and acute pyelonephritis, Lipin is injected intravenously at a dose of 10-20 mg / kg of body weight once a day, simultaneously with antibacterial agents. The duration of the course is 3-4 days.

In the treatment of chronic pyelonephritis, glomerulonephritis, diabetic nephropathy at the stage of chronic renal failure, Lipin is administered intravenously in the same dose at the same time as standard basic therapy. The duration of the course is 14 days.

Side effects

When used in therapeutic doses, Lipin is usually well tolerated.

During therapy, palpitations, headaches, urticaria and other allergic manifestations may occur.

In some cases (after intravenous administration of Lipin), the following may develop:

General reactions: fever, tremors of the extremities, decreased blood pressure, weakness, vomiting, pain in the lumbar spine, lumbago in the thoracic and lumbar spine;
Local reactions: pain along the vein.

With the development of these disorders, Lipin should be canceled and symptomatic therapy should be prescribed.

special instructions

Before starting the use of Lipin, as well as in cases of the development of uncharacteristic symptoms, you should consult a doctor.

Drug interactions

Simultaneous use of Lipin with cytostatic, steroid, antibiotic, vitamin and choleretic drugs is possible.

Analogs

Lipin's analogs are: Swage collagen beauty drink, Neocardil, Folio, L-carnitine, Lida (Lida).

Terms and conditions of storage

Keep out of reach of children at temperatures from -10 to -20 ° C (in the freezer).

Expiration date - 1 year.

The prepared emulsion can be stored for up to 6 hours at a temperature of 2-6 ° C.

Terms of dispensing from pharmacies

Dispensed by prescription.

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!