Lincomycin - Instructions For Use, Description, Reviews

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Lincomycin

Instructions for use:

1. 1. Pharmacological action
2. 2. Release form
3. 3. Indications for use
4. 4. Contraindications to use
5. 5. Instructions for use
6. 6. Side effects
7. 7. Storage conditions

Prices in online pharmacies:

from 54 rubles.

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Lincomycin is an antibiotic used to treat various diseases caused by most Gram-positive bacteria.

pharmachologic effect

Lincomycin, being an antibiotic, is active in therapeutic doses against:

• Streptococcus spp. Including Streptococcus pneumoniae;
• Bacteroides spp.;
• Mycoplasma spp.;
• Staphylococcus spp., Including strains that produce penicillinase;
• Corynebacterium diphtheriae;
• Clostridium spp.

According to the instructions, Lincomycin does not affect most gram-negative bacteria, viruses, Enterococcus faecalis, fungi and protozoa.

Lincomycin slowly develops resistance, is rapidly distributed in tissues and body fluids, including bone tissue, and crosses the placental barrier.

When using Lincomycin, it should be borne in mind that there is cross-resistance between clindamycin and the drug.

Release form

Lincomycin is available as:

• Lincomycin capsules, white with a yellow cap, containing 250 mg of the active ingredient - lincomycin hydrochloride, in the form of a white powder, 10, 20, 360 pieces per package;
• 2% ointment for external use, 10 or 15 g in tubes;
• Solution for intramuscular and intravenous administration of Lincomycin hydrochloride, containing 300 or 600 mg of active ingredient in an ampoule, 5, 10, 100 ampoules per package.

Indications for the use of Lincomycin

According to the instructions, Lincomycin is used for the treatment of severe infectious and inflammatory diseases, including:

• Septic endocarditis;
• Pneumonia;
• Sepsis;
• Lung abscess;
• Wound infections;
• Osteomyelitis;
• Empyema of the pleura.

Lincomycin ointment is used topically in the treatment of purulent-inflammatory skin diseases.

In dentistry, Lincomycin is used to treat various infections of the maxillofacial system. Its main advantage over other antibiotics is its ability to be deposited in bone tissue and teeth.

Quite often, Lincomycin is used in dentistry together with lidocaine to eliminate purulent processes in gingivitis, periodontitis or periodontitis.

Lincomycin is also used to avoid the attachment of a secondary infection to the wound surface in the area of the hole after tooth extraction. There is no unequivocal opinion about the advisability of using the drug in these cases.

Also, there are no direct indications in the instructions for the use of Lincomycin in dentistry, so the question of its use must be resolved with a doctor.

Contraindications to the use of Lincomycin

According to the description, Lincomycin is contraindicated in case of sensitivity to the active substances of the drug (clindamycin or lincomycin), as well as in severe renal and hepatic impairment.

The use of Lincomycin is contraindicated during lactation and pregnancy due to the penetration of the drug through the placental barrier.

Instructions for the use of Lincomycin

When taking Lincomycin in capsules, 500 mg is used 3-4 times a day. Typically, the duration of treatment is one to two weeks, with osteomyelitis - up to three weeks or more. Lincomycin capsules are taken several hours before meals with a small amount of liquid.

Intravenous Lincomycin according to the instructions is used up to 2 times a day, 600 mg.

Intravenous Lincomycin hydrochloride is used drip, 600 mg several times a day.

Children are prescribed Lincomycin capsules in a daily dose, calculated as 30-60 mg per 1 kg of body weight.

If necessary, Lincomycin hydrochloride is administered intravenously every 8-12 hours at the rate of 10-20 mg per 1 kg of body weight.

When applied topically in the form of an ointment, Lincomycin is applied in a thin layer to the affected skin several times a day. The ointment is used with caution in dermatomycosis and fungal skin diseases.

With the simultaneous use of Lincomycin with cephalosporins, penicillins, erythromycin or chloramphenicol, antagonism of the antimicrobial action may occur, and with simultaneous use with aminoglycosides - synergism of action.

With caution, Lincomycin should be used simultaneously with peripheral muscle relaxants and for inhalation anesthesia because of the possibility of increasing neuromuscular blockade, sometimes leading to the development of apnea.

Antidiarrheal drugs lead to a decrease in the bactericidal effect of Lincomycin.

When using Lincomycin, it should be borne in mind that the drug is not pharmaceutically compatible with:

• Novobiocin;
• Kanamycin;
• Barbiturates;
• Calcium gluconate;
• Heparin;
• Ampicillin;
• Theophylline;
• Magnesium sulfate.

Side effects of Lincomycin

According to the instructions and reviews, Lincomycin can cause the following side effects:

• Glossitis;
• Epigastric pain;
• Reversible leukopenia;
• Stomatitis;
• Exfoliative dermatitis;
• Diarrhea;
• Anaphylactic shock;
• Increased levels of hepatic transaminases and bilirubin in blood plasma;
• Nausea;
• Candidiasis;
• Neutropenia;
• Vomiting;
• Thrombocytopenia
• Hives;
• Quincke's edema.

With prolonged use of Lincomycin in high doses, the development of pseudomembranous colitis is possible.

With intravenous use, phlebitis can develop, with rapid intravenous administration, general weakness, dizziness, relaxation of skeletal muscles and a decrease in blood pressure can be observed.

Storage conditions

Lincomycin is available by prescription. According to the description, the shelf life of Lincomycin capsules is 4 years, solution for injection and ointment is 3 years.

Lincomycin: prices in online pharmacies

Drug name Price Pharmacy

Lincomycin 250 mg capsule 20 pcs. RUB 54 Buy

Lincomycin 250 mg capsule 20 pcs. RUB 58 Buy

Lincomycin 250 mg capsule 20 pcs. RUB 78 Buy

Lincomycin capsules 250mg 20 pcs. RUB 85 Buy

Lincomycin 250 mg capsule 20 pcs. RUB 99 Buy

Lincomycin ointment 2% 15g RUB 105 Buy

Lincomycin (for injection) 300 mg / ml solution for intravenous and intramuscular administration 1 ml 10 pcs. 120 RUB Buy

Lincomycin hydrochloride solution for in. 30% 1ml 10 pcs. RUB 128 Buy

Lincomycin capsules 250mg 20 pcs. 129 RUB Buy

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Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!