Lincomycin-AKOS
Lincomycin-AKOS: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews
- 16. Price in pharmacies
Latin name: Lincomycin-AKOS
ATX code: D06AX
Active ingredient: lincomycin (Lincomycin)
Manufacturer: JSC Sintez (Russia)
Description and photo update: 2019-08-10
Prices in pharmacies: from 59 rubles.
Buy
Lincomycin-AKOS is a bacteriostatic drug for external use.
Release form and composition
The drug is produced in the form of an ointment for external use, which is a white or white homogeneous mass with a yellowish tinge (10 g or 15 g each in aluminum tubes, one tube in a cardboard box and instructions for the use of Lincomycin-AKOS).
Composition per 100 g of ointment:
- active substance: lincomycin (in the form of lincomycin hydrochloride) - 2 g;
- auxiliary components: potato starch, medical petroleum jelly, zinc oxide, solid paraffin.
Pharmacological properties
Pharmacodynamics
Lincomycin is an antibiotic produced by Streptomyces lincolniensis or other related actinomycetes. It acts bacteriostatically, suppressing protein synthesis in the bacterial cell due to reversible binding to the ribosomal 50S subunit and disrupting the formation of peptide bonds.
The drug is active against the following microorganisms: Streptococcus spp. (including Streptococcus pneumoniae), Bacillus anthracis, Staphylococcus spp., Haemophilus influenzae, Bacteroides spp., Clostridium tetany and Clostridium perfringens, Mycoplasma spp., Corynebacterium diphtheriae.
Strains of Staphylococcus spp. Resistant to tetracyclines, cephalosporins, penicillin, streptomycin, chloramphenicol are susceptible to lincomycin. Therefore, Lincomycin-AKOS can be considered as a reserve drug (only 30% of Staphylococcus spp. That are resistant to erythromycin have cross-resistance to lincomycin).
The drug has no effect on gram-negative strains of bacteria, Enterococcus spp. (including Enterococcus faecalis), protozoa, viruses and fungi; lincomycin is inferior in activity to erythromycin against Corynebacterium spp., Neisseria spp. and spore-forming anaerobes.
The optimal effect of Lincomycin-AKOS is manifested in an alkaline medium (from pH 8 to pH 8.5).
Lincomycin resistance develops slowly (according to the penicillin type). In large doses, the drug has a bactericidal effect.
Pharmacokinetics
Data on the pharmacokinetics of lincomycin when applied topically are not provided.
Indications for use
Lincomycin-AKOS ointment is used for purulent-inflammatory diseases of soft tissues and skin caused by microorganisms sensitive to lincomycin: furunculosis, erysipelas, pyoderma, phlegmon, etc.
Contraindications
The ointment is contraindicated in early infancy (up to one month), pregnant women (except in emergency cases, when the use of the drug is vital), as well as patients with hypersensitivity to the main or auxiliary components of the drug.
Lincomycin-AKOS is used with caution in fungal skin diseases.
Lincomycin-AKOS, instructions for use: method and dosage
The drug is intended for external use.
Lincomycin-AKOS ointment is applied to the affected skin with a thin layer 2-3 times a day.
Side effects
Allergic reactions are possible (manifested by exfoliative dermatitis or urticaria).
Overdose
To date, no cases of drug overdose have been registered.
special instructions
The ointment should be used with caution in patients with dermatomycosis.
Application during pregnancy and lactation
The drug is not recommended for pregnant women (unless the use of lincomycin is vital).
During the period of breastfeeding, the ointment can be applied only to limited areas of the skin, in small doses and as short a course as possible.
Pediatric use
Lincomycin-AKOS should not be used in infants (up to one month).
Drug interactions
With erythromycin, antagonism of the action of lincomycin is manifested, and with aminoglycosides, synergism.
Pharmaceutically, lincomycin is incompatible with ampicillin, kanamycin and novobiocin.
Analogs
Lincomycin-AKOS analogs are Lincomycin hydrochloride, LinkoVel, Lincomycin, KMP-Lincomycin, Ekolink, etc.
Terms and conditions of storage
Keep out of the reach of children at a temperature of + 15 … + 25 ° C.
The shelf life of the ointment is 2 years.
Terms of dispensing from pharmacies
Dispensed by prescription.
Reviews about Lincomycin-AKOS
According to reviews, Lincomycin-AKOS is a good wound healing, anti-inflammatory and drying agent. The drug is suitable for both adults and children. Almost no contraindications and side effects. Odorless and tasteless ointment, inexpensive. The main drawback, according to patients, is that the drug belongs to antibiotics.
Price for Lincomycin-AKOS in pharmacies
The price of Lincomycin-AKOS in the form of an ointment for external use 2% (15 g each in aluminum tubes) is about 70-80 rubles.
Lincomycin-AKOS: prices in online pharmacies
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Drug name Price Pharmacy |
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Lincomycin-AKOS 2% ointment for external use 15 g 1 pc. RUB 59 Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
