Calcium-D3 Nycomed Forte
Calcium-D3 Nycomed Forte: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. In case of impaired renal function
- 12. For violations of liver function
- 13. Use in the elderly
- 14. Drug interactions
- 15. Analogs
- 16. Terms and conditions of storage
- 17. Terms of dispensing from pharmacies
- 18. Reviews
- 19. Price in pharmacies
Latin name: Calcium-D3 Nycomed Forte
ATX code: A12AX
Active ingredient: Colecalciferol + Calcium carbonate (Colecalciferol + Calcium carbonate)
Manufacturer: Nycomed Pharma AS (Norway)
Description and photo update: 2018-24-10
Prices in pharmacies: from 365 rubles.
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Calcium-D3 Nycomed Forte is a product containing calcium and vitamin D 3, which compensates for their deficiency.
Release form and composition
Lemon chewable tablets: round, biconvex, white, without a shell, with a lemon aroma; there may be small inclusions and uneven edges.
Packing: vials with a screw cap - 30, 60 and 120 pcs., Each bottle in a cardboard box.
Composition of 1 tablet:
- active ingredients: calcium carbonate - 1250 mg, which is equivalent to 500 mg of elemental calcium, colecalciferol (vitamin D 3) - 400 IU (0.01 mg), in the form of colecalciferol concentrate (4 mg);
- additional components: aspartame, sorbitol, mono- and diglycerides of fatty acids, povidone, isomalt, lemon oil, magnesium stearate.
Pharmacological properties
Pharmacodynamics
Calcium-D3 Nycomed Forte, thanks to its components, regulates the exchange of calcium and phosphorus in the body (in bones, nails, teeth, muscles, hair). Replenishing the deficiency of vitamin D 3 and calcium, reduces bone resorption and increases its density, participates in the mineralization of teeth.
In addition, calcium is a component of the blood coagulation system and is involved in the regulation of muscle contractions and nerve conduction. Vitamin D 3 promotes better absorption of calcium in the intestines.
The use of calcium in combination with vitamin D 3 prevents an increase in the production of parathyroid hormone, which stimulates the leaching of calcium from the bones (increased bone resorption).
Pharmacokinetics
Calcium is absorbed in the gastrointestinal tract in an amount of about 30% of the dose taken. 99% of the substance present in the human body is concentrated in the rigid structure of bones and teeth, another 1% - in extra- and intracellular fluids. About 50% of the calcium in the blood is presented in a physiologically active ionized form, of which about 40% are bound to proteins (mainly albumin), the remaining 10% are present in a complex with phosphate, citrate or other anions. Calcium is excreted by the intestines, kidneys, sweat glands. In the latter case, excretion depends on tubular calcium reabsorption and glomerular filtration.
Colecalciferol is absorbed in the small intestine in an amount of about 80% of the dose taken. Vitamin D 3 and its metabolites circulate in the blood, binding to specific globulin. Colecalciferol is metabolized in the liver by hydroxylation to 25-hydroxycolecalciferol, after which it is converted in the kidneys into the active metabolite 1,25-hydroxycolecalciferol, which is responsible for enhancing calcium absorption. Unmetabolized cholecalciferol is deposited in muscle and adipose tissue. It is excreted by the intestines and kidneys.
Indications for use
Prevention and treatment:
- calcium and / or vitamin D 3 deficiency;
- osteoporosis and its complications (bone fractures).
Contraindications
- children under 3 years old;
- hypersensitivity to peanuts or soy;
- hypercalciuria;
- hypercalcemia;
- hypervitaminosis D;
- sarcoidosis;
- active tuberculosis;
- hereditary fructose intolerance, glucose-galactose malabsorption, sucrose-isomaltase deficiency;
- phenylketonuria;
- kidney stone disease;
- severe renal failure;
- individual sensitivity to any component of the drug.
Calcium-D3 Nycomed Forte only on the recommendation of a doctor and under his supervision should be used during pregnancy and lactation, patients with renal insufficiency.
Instructions for use of Calcium-D3 Nycomed Forte: method and dosage
Calcium-D3 Nycomed Forte tablets should be taken with meals: dissolve in the mouth or chew.
To replenish the lack of vitamin D 3 and calcium, they are prescribed: adults and adolescents from 12 years old - 2 tablets per day, children from 3 to 12 years old - 1 tablet per day, unless otherwise prescribed by a doctor.
The duration of admission is on average 4-6 weeks. The need for repeated courses and their number during the year is determined by the doctor individually.
For the prevention of osteoporosis, it is recommended to take 2 tablets 1 time per day or 1 tablet 2 times a day. As part of the complex therapy of osteoporosis, Calcium-D3 Nycomed Forte is prescribed 1 tablet 2 or 3 times a day. The duration of taking the drug is determined individually.
Side effects
During therapy, undesirable reactions may occur:
- from the digestive system: rarely - dysfunction of the gastrointestinal tract (increased gas formation in the intestines, abdominal pain, nausea, dyspepsia, diarrhea or constipation);
- allergic reactions: very rarely - skin rashes, itching, urticaria;
- laboratory parameters: infrequently - hypercalciuria and hypercalcemia (increased calcium in the urine or blood).
Overdose
An overdose of calcium is manifested by hypercalcemia, its possible symptoms: thirst, abdominal pain, constipation, nausea, anorexia, vomiting, muscle weakness, fatigue, mental disorders, bone pain, increased urine production, urolithiasis, nephrocalcinosis. In severe cases, cardiac arrhythmias may develop. With prolonged intake of high doses of calcium (more than 2500 mg), calcification of soft tissues is noted, kidney damage is possible.
In case of an overdose, it is necessary to cancel Calcium-D3 Nycomed Forte, as well as, if used simultaneously, cardiac glycosides and thiazide diuretics.
The first measures: gastric lavage and replenishment of fluid loss.
Overdose treatment: the use of calcitonin, glucocorticosteroids, bisphosphonates, loop diuretics (eg, furosemide). Patients should be monitored for plasma electrolytes, urine output and renal function; in severe overdose symptoms, it is recommended to measure central venous pressure and monitor the electrocardiogram.
special instructions
It is important to consider additional vitamin D intake from any other source, including food, to avoid overdose.
With prolonged use of the drug, it is necessary to control the level of calcium and creatinine in the blood serum, especially in the elderly, receiving simultaneously diuretics and / or cardiac glycosides, as well as in patients with an increased tendency to form kidney stones. When symptoms of impaired renal function or the development of hypercalcemia appear, the dose of Calcium-D3 Nycomed Forte should be reduced or canceled altogether.
The drug should be used with caution in the treatment of patients with osteoporosis if they are immobilized, as this category is at increased risk of developing hypercalcemia.
It is not recommended to simultaneously prescribe quinolone and tetracycline antibiotics. Caution should be exercised if such combinations are justified.
Influence on the ability to drive vehicles and complex mechanisms
The active ingredients Calcium-D3 Nycomed Forte do not affect a person's ability to drive vehicles and work with technically complex mechanisms.
Application during pregnancy and lactation
According to the instructions, Calcium-D3 Nycomed Forte is prescribed during pregnancy and lactation to compensate for the lack of calcium and vitamin D 3.
For pregnant women, daily doses of vitamins should not exceed: calcium - 1500 mg, colcalciferol - 600 IU. This should be taken into account, since hypercalcemia may develop as a result of an overdose, and it has a negative effect on the development of the fetus.
Vitamin D 3 and its metabolites pass into breast milk, therefore, nursing mothers need to take into account the intake of cholecalciferol and calcium from other sources, both in themselves and in the baby.
Pediatric use
Calcium-D3 Nycomed Forte is contraindicated in children under 3 years of age (due to the dosage form in the form of tablets).
With impaired renal function
Severe renal failure and nephrolithiasis are contraindications to the administration of the drug.
In renal failure, caution should be exercised, control of serum calcium and phosphate levels, and the risk of soft tissue calcification should be taken into account.
For violations of liver function
No dose adjustment is required in patients with impaired hepatic function.
Use in the elderly
Elderly people do not need to adjust the dose, but the possibility of an age-related decrease in creatinine clearance cannot be ruled out.
Drug interactions
Calcium can reduce the absorption of tetracyclines and quinolone from the gastrointestinal tract, so they should be taken at least 2 hours before taking Calcium-D3 Nycomed Forte or 4–6 hours after.
Calcium absorption decreases with the simultaneous use of glucocorticosteroids, so an increase in its dose may be required.
The absorption of bisphosphonates decreases with the combined use of calcium supplements, so they should be taken at least 1 hour before Calcium-D3 Nycomed Forte. A similar situation with the use of levothyroxine, but in this case it is recommended to make an interval of at least 4 hours between doses.
Thiazide diuretics increase tubular calcium reabsorption and, as a consequence, the risk of increased serum levels, so monitoring is required.
Hypercalcemia can increase the toxic effects of cardiac glycosides, therefore, it is necessary to monitor the electrocardiogram and the level of calcium in the blood serum.
Calcium absorption is reduced by foods containing oxalates (spinach, rhubarb, sorrel) and phytin (cereals), so it is recommended to refrain from eating them for 2 hours before taking Calcium-D3 Nycomed Forte.
Analogs
Analogues of Calcium-D3 Nycomed Forte: Natemille, Revital Calcium D 3, Calcium-D 3- MIG, Calcium D 3 Classic, Ideos, Complivit calcium D 3, Complivit calcium D 3 forte, Natekal D 3, Calcium-D 3 Nycomed, Calcium + Vitamin D 3 Vitrum.
Terms and conditions of storage
Storage conditions: tightly closed bottle, temperature up to 25 ° С, dry place out of reach of children.
Shelf life - 3 years from the date of production.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Calcium-D3 Nycomed Forte
On specialized medical forums, you can find mainly positive reviews about Calcium-D3 Nycomed Forte. Patients note the ease of administration, the pleasant taste of the tablets, and the effectiveness of the drug. In particular, there are statements that after eliminating the deficiency of calcium and vitamin D 3, bone fractures heal faster, the condition of nails and hair improves, as well as the condition of the joints during active sports.
The disadvantage of the drug, many consider its relatively high cost.
Price for Calcium-D3 Nycomed Forte in pharmacies
Approximate prices for Calcium-D3 Nycomed Forte: 30 tablets - 265-295 rubles, 60 tablets - 385-420 rubles, 120 tablets - 520-535 rubles.
Calcium-D3 Nycomed Forte: prices in online pharmacies
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Drug name Price Pharmacy |
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Calcium-D3 Nycomed Forte 500 mg + 400 IU lemon chewable tablets 60 pcs. 365 RUB Buy |
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Calcium-D3 Nycomed Forte 500 mg + 400 IU lemon chewable tablets 120 pcs. 418 RUB Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
