Hydroxyapatite
Instructions for use:
- 1. Dosage form
- 2. Pharmacological action
- 3. Indications for use
- 4. Contraindications
- 5. Side effects
- 6. Instructions for use
- 7. Special instructions
- 8. Storage conditions
Calcium hydroxyapatite Ca 10 (PO 4) 6 (OH) 2 is an inorganic basic component of bone tissue.
The preparation Hydroxyapatite is produced from corals of the genus Porites, which are mined in the sea. It is absolutely inert to human tissues, due to this it has been widely used in dentistry, traumatology, maxillofacial surgery. In cosmetology, Hydroxyapatite is used to smooth wrinkles.
Pharmacological group: regulator of calcium-phosphorus metabolism
Dosage form
Calcium hydroxyapatite is available in the form of powder, suspension, granules and paste.
pharmachologic effect
By regulating the exchange of calcium and phosphorus, the agent itself is the base of the bone tissue matrix with an inorganic nature. By activating osteogenesis, the proliferation of osteoblasts increases and the process of reparative osteogenesis is triggered at the injection site, which inhibits the inflammatory process in the bone wound. After the bone cavity is filled, calcium hydroxyapatite does not harden and does not dissolve, but is replaced with full-fledged bone tissue.
Calcium hydroxyatite is low-toxic, with its use there are no side effects (inflammation, allergies, mutagenic effects).
Indications for the use of Hydroxyapatite
To stimulate reparative osteogenesis in maxillofacial and plastic surgery, in traumatology and dentistry, Hydroxyapatite is used:
- as the execution of the missing elements of bone tissue;
- with periodontitis;
- for restoration of bone defects after removal of sequesters;
- for injuries with damage to bone tissue (eg gunshot);
- with different types of fractures;
- with the formed false joints;
- for the introduction of endoprostheses and implants;
- with plastic surgery of the facial bones.
For use as an ingredient, a filler of dental filling pastes, Hydroxyapatite is used when:
- pulpitis;
- periodontitis;
- replenishment of bone defects - after a removed cyst;
- replenishment of defects after resection (partial removal) of the apex of the tooth root;
- deep caries;
- for filling root canals.
Hydroxyapatite is also used in cosmetology for intradermal injections, for smoothing wrinkles.
Contraindications
In case of individual hypersensitivity to the drug.
Side effects
Not visible.
Instructions for the use of Hydroxyapatite
Powder of calcium hydroxyapatite is mixed with saline and ethyl glycol or with an oily solution of retinol acetate to a pasty consistency. The paste must be used within two minutes after preparation.
Calcium hydroxyapatite granules are used to fill pockets in periodontitis. To do this, prepare a pocket in advance, and then fill it tightly with granules.
Hydroxyapatite in the form of a ready-made paste can be immediately injected into the injured, previously prepared part of the bone (removing the altered or necrotic tissue) or the place where it is necessary to fill the defect, followed by layer-by-layer stitching of the soft tissues.
5% The suspension is injected into the cavity of the bone tissue defect using a syringe.
To restore the previous height of the interalveolar septa and fill the defect in the alveolar process, 45% paste is used.
For the treatment of periodontitis, 18% hydroxyapatite paste is used.
10% hydroxyapatite suspension is used in cases of conservative treatment of periodontitis.
To smooth out wrinkles in cosmetology, Hydroxyapatite is introduced by intradermal injection as a filler in the form of an aqueous solution.
special instructions
The use of the drug for the restoration of bone tissue, in the acute phase of soft tissue inflammation accompanied by suppuration, is considered inappropriate.
If necessary, Hydroxyapatite can be sterilized in a dry heat cabinet with an unlimited repetition rate at temperatures up to 150 C, with an exposure of at least 10-15 minutes.
Storage conditions
Store in a dry place.
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
