Flucor
Flukorem: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Drug interactions
- 11. Analogs
- 12. Terms and conditions of storage
- 13. Terms of dispensing from pharmacies
- 14. Reviews
- 15. Price in pharmacies
Latin name: Flucorem
ATX code: J02AC01
Active ingredient: fluconazole (Fluconazole)
Manufacturer: Inkub Ethicals Pvt. Ltd. (Encube Ethicals Pvt. Ltd.) (India)
Description and photo updated: 2020-19-03
Flukorem is an antifungal drug for external use with a wide spectrum of action.
Release form and composition
The drug is produced in the form of a gel for external use, 0.5%: a homogeneous colorless opalescent mass (15 or 30 g each in aluminum tubes, in a cardboard box 1 tube and instructions for the use of Flucorem).
1 g of gel contains:
- active substance: fluconazole - 5 mg;
- auxiliary components: propylene glycol, propyl parahydroxybenzoate, methyl parahydroxybenzoate, diethylamine, disodium edetate, carbomer, macrogol 400, purified water.
Pharmacological properties
Pharmacodynamics
Flukorem is an antifungal drug with a wide spectrum of action for topical and external use. Its active ingredient, fluconazole, is a triazole derivative. The mechanism of action of the drug is due to the blockade of cytochrome P 450 as a result of selective inhibition of sterol synthesis in fungal cell membranes.
The use of fluconazole is effective in the treatment of opportunistic mycoses, including those caused by Microsporum speciales (spp.), Trichophyton spp., Candida spp. (including generalized forms of candidiasis against the background of immunosuppression), Cryptococcus neoformans, Coccidioides immitis (including intracranial infections).
In case of endemic mycoses, such microorganisms as Blastomyces dermatitidis, Histoplasma capsulatum are sensitive to fluconazole (including during immunosuppression).
When applied topically and externally, its activity has been established against dermatophytes, fungi (yeasts and molds) and microorganisms that cause dermatomycosis [Pityriasis versicolor, or pityriasis versicolor] and cutaneous candidiasis (Trichophyton spp., Candida spp., Microsporum spp., Epidermophyton spp., Malassezia furfur or Pityrosporum orbiculare).
Pharmacokinetics
When applied externally, fluconazole is almost not absorbed, therefore it has no systemic effect.
Indications for use
The use of Flucorem gel is indicated for the treatment of superficial fungal infections of the skin, including the following diseases:
- mycosis or fungal infection of the feet;
- fungal lesions of the smooth skin of the body (tinea corporis);
- epidermophytosis inguinal (tinea cruris);
- yeast infections of the skin caused by fungi of the genus Candida (including Candida albicans), diaper rash;
- versicolor versicolor (Pityriasis versicolor) caused by Pityrosporum orbiculare.
Contraindications
Absolute:
- I trimester of pregnancy;
- a history of hypersensitivity to azole compounds;
- individual intolerance to the components of the drug.
Flucor should be used with caution in the II and III trimesters of pregnancy and during breastfeeding.
Flukorem, instructions for use: method and dosage
Flukorem gel is applied externally by applying a uniform thin layer and rubbing until it is completely absorbed into the skin at the affected area and at least 2 cm of the adjacent area.
The procedure is recommended to be carried out 2 times a day (morning and evening). The duration of the course of treatment depends on the causative agent of the infection and the place of its localization, so it can last from 7 to 21 days (for some resistant forms, the duration of therapy, on the recommendation of a doctor, can be extended to 42 days).
In the absence of a therapeutic effect, it is necessary to conduct appropriate studies to clarify the diagnosis.
Side effects
- local reactions: rarely - burning sensation, skin irritation;
- allergic reactions: skin rash, urticaria.
Overdose
Symptoms of an overdose of Flucorem have not been established.
special instructions
Flucor should be used only on the recommendation of a doctor!
Do not use the drug to treat ophthalmic infections. Avoid accidental eye contact with the gel.
The appearance of skin irritation or symptoms of hypersensitivity is the basis for immediate discontinuation of therapy.
Influence on the ability to drive vehicles and complex mechanisms
External use of fluconazole does not affect the ability of patients to drive vehicles and other mechanisms.
Application during pregnancy and lactation
The use of Flucorem is contraindicated in the first trimester of pregnancy.
With caution and only as directed by a doctor, it is allowed to use the gel in the II and III trimesters of pregnancy and during breastfeeding.
Drug interactions
With the simultaneous use of Flucorem with other drugs, no clinically significant interaction has been established.
The combination of the gel with other topical preparations is allowed only as directed by a doctor.
Analogs
Flukorem analogs are Fluconazole, Binnoflunazole, Vero-Fluconazole, Disorel-Sanovel, Diflazon, Diflucan, Mikomax, Mikosist, Maykonil, Medoflucon, Mikoflucan, Procanazol, Nofung, Fangiflu, Flucosidol, Flucogentizol, Fluconorm, Forcan, Tsiskan, etc.
Terms and conditions of storage
Keep out of the reach of children.
Store at temperatures up to 25 ° C, protected from moisture and light.
Shelf life is 2 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Flucorem
Reviews about Flucorem, left by experts, are positive. They indicate the high efficacy of fluconazole in the treatment of various dermatomycosis and the good tolerance of the gel.
The price of Flucorom in pharmacies
The price of Flucorom for a package containing 1 tube of 15 g gel varies within the range of 250–386 rubles.
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
