Aquatsitramon - Instructions For Use, Reviews, Price, Analogues Of Granules

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Aquacitramon

Aquatsitramon: instructions for use and reviews

1. 1. Release form and composition
2. 2. Pharmacological properties
3. 3. Indications for use
4. 4. Contraindications
5. 5. Method of application and dosage
6. 6. Side effects
7. 7. Overdose
8. 8. Special instructions
9. 9. Application during pregnancy and lactation
10. 10. Use in childhood
11. 11. In case of impaired renal function
12. 12. For violations of liver function
13. 13. Drug interactions
14. 14. Analogs
15. 15. Terms and conditions of storage
16. 16. Terms of dispensing from pharmacies
17. 17. Reviews
18. 18. Price in pharmacies

Latin name: Aquacitramon

ATX code: N02BA51

Active ingredient: acetylsalicylic acid (Acetylsalicylic acid), paracetamol (Paracetamol), caffeine (Caffeine)

Producer: LLC "Agrofitofarm" (Russia)

Description and photo update: 2019-10-07

Prices in pharmacies: from 135 rubles.

Buy

Aquacitramone is a non-narcotic analgesic of a combined composition.

Release form and composition

The drug is produced in the form of granules for the preparation of a solution for oral administration: from white to white with a creamy shade of color, with a faint smell of lemon [3 g each in single-dose, cell-free contour packs (bags), in a cardboard box 5 or 10 packs and instructions for use of Aquacitramon].

The composition of the drug in 1 package:

• active substances: acetylsalicylic acid - 360 mg, paracetamol - 270 mg, caffeine - 45 mg;
• auxiliary components: sodium bicarbonate, saccharin, low molecular weight polyvinylpyrrolidone, lactose, sodium cyclamate, citric acid, flavor.

Pharmacological properties

Pharmacodynamics

The effects of Aquacitramon are due to the properties of its active ingredients:

• acetylsalicylic acid (ASA) is a non-steroidal anti-inflammatory agent with antipyretic action. Relieves pain, especially caused by the inflammatory process. Improves microcirculation in the focus of inflammation. Moderately inhibits platelet aggregation and thrombus formation;
• paracetamol is an analgesic-antipyretic, which has an analgesic, antipyretic and weak anti-inflammatory effect, which is due to its pronounced effect on the center of thermoregulation in the hypothalamus and a weak inhibition of prostaglandin synthesis in peripheral tissues;
• caffeine is a psychostimulant that increases the reflex excitability of the spinal cord, excites the respiratory and vasomotor centers, reduces platelet aggregation, dilates the blood vessels of the brain, skeletal muscles, kidneys and heart. Reduces the feeling of tiredness and sleepiness, increases physical and mental performance. In the composition of Aquacitramon, caffeine is included in a small dose, therefore, it practically does not have a stimulating effect on the central nervous system, but it accelerates blood flow and normalizes the tone of the cerebral vessels.

Pharmacokinetics

Information not provided by the manufacturer.

Indications for use

• mild and moderate pain syndrome in adults, including toothache and headache, arthralgia, lumbago, neuralgia, chest radicular syndrome, myalgia, algomenorrhea;
• increased body temperature against the background of colds and other infectious and inflammatory diseases in adults and adolescents from 15 years old.

Contraindications

Absolute:

• increased tendency to bleeding;
• erosive and ulcerative lesions of the gastrointestinal tract in the acute phase;
• gastrointestinal bleeding;
• surgical interventions accompanied by bleeding;
• portal hypertension;
• severe course of coronary heart disease;
• dissecting aortic aneurysm;
• deficiency of glucose-6-phosphate dehydrogenase;
• vitamin K deficiency;
• hemorrhagic diathesis (thrombocytopenia, thrombocytopenic purpura, hypoprothrombinemia, von Willebrand disease, hemophilia, telangiectasia);
• aspirin asthma;
• renal failure;
• glaucoma;
• sleep disorders;
• increased excitability;
• I and III trimesters of pregnancy;
• lactation period;
• age up to 15 years (with acute respiratory diseases caused by viral infections) - as an antipyretic agent;
• age up to 18 years - as an anesthetic;
• hypersensitivity to any component of the drug.

Relative (Aquacitramon granules should be used with caution):

• history of gastric ulcer and / or duodenal ulcer;
• urate nephrolithiasis;
• hyperuricemia;
• gout;
• decompensated heart failure;
• liver disease;
• II trimester of pregnancy (provided that the benefits to the mother exceed the risk to the fetus).

Aquatsitramon, instructions for use: method and dosage

Aquacitramon granules should be taken orally after meals, dissolving the contents of the package in 100 ml of water (a slight sediment may remain in the glass). It is necessary to prepare the solution immediately before taking.

The recommended dose is 1 packet 2-3 times a day at intervals of at least 4 hours. The maximum allowable daily dose is 6 packets.

Patients with impaired liver or kidney function should increase the interval between doses to at least 6 hours.

The duration of treatment should not exceed 5 days if Aquacitramone is used to relieve pain, and 3 days if used to reduce fever.

Other doses and dosing regimens can only be prescribed by a doctor.

Side effects

• from the digestive system: nausea, vomiting, gastralgia, anorexia, erosive and ulcerative lesions of the gastrointestinal tract, hepatotoxicity;
• from the urinary system: nephrotoxicity;
• on the part of the cardiovascular system: increased blood pressure, tachycardia;
• allergic reactions: skin rashes, Stevens-Johnson syndrome, bronchospasm, Lyell's syndrome.

With prolonged use of Aquatsitramon, the following violations may occur:

• tinnitus, deafness, visual impairment, headache, dizziness;
• kidney damage with papillary necrosis;
• hypocoagulation, decreased platelet aggregation, hemorrhagic syndrome (including bleeding gums, nosebleeds, purpura);
• Reye's syndrome in children (disorders of the nervous system and psyche, metabolic acidosis, vomiting, hyperpyrexia, liver dysfunction).

Overdose

Symptoms: pallor of the skin, sweating, stomach pain, nausea, vomiting, ringing in the ears, tachycardia. With severe intoxication, drowsiness, incoherent thinking, bleeding, anuria, shortness of breath, bronchospasm, convulsions, collapse may also occur. As the poisoning intensifies, progressive respiratory paralysis develops, oxidative phosphorylation is uncoupled, which causes respiratory acidosis.

In case of suspicion of intoxication, you should urgently seek medical help. The patient is given gastric lavage, adsorbents and symptomatic therapy are prescribed.

special instructions

With long-term treatment, it is necessary to monitor the peripheral blood parameters and the functional state of the liver.

ASA slows down blood clotting, therefore, patients should warn the doctor in advance about taking Aquacitramon if they have to undergo surgery.

In low doses, ASA reduces the excretion of uric acid, which in some cases can cause a gout attack.

During the period of therapy, it is recommended to refrain from drinking alcoholic beverages, since ethanol increases the risk of gastrointestinal bleeding.

For patients with hypersensitivity or asthmatic reactions to salicylates or their derivatives, Aquacitramone can only be prescribed with special precautions (in an emergency service).

Application during pregnancy and lactation

ASA has a teratogenic effect: in the first trimester of pregnancy it can cause splitting of the upper palate in the fetus, in the third trimester - inhibition of labor in the mother, as well as closure of the ductus arteriosus in the fetus, which is fraught with hyperplasia of the pulmonary vessels and the development of hypertension in the vessels of the pulmonary circulation. In the I and III trimesters of pregnancy, Aquacitramone is contraindicated. In the II trimester, it can be used only in cases of extreme necessity, if the expected benefit outweighs the potential risks.

ASA passes into mother's milk and increases the risk of bleeding in an infant (due to dysfunction of platelets). During lactation, taking Aquacitramon is contraindicated, or you should consider stopping breastfeeding during therapy.

Pediatric use

As an anesthetic, Aquacitramon is contraindicated in patients under the age of 18. As an antipyretic agent, it is forbidden to give it to children and adolescents under 15 years of age, since in acute respiratory diseases caused by viral infections, ASA increases the risk of Reye's syndrome (encephalopathy and acute fatty liver disease with acute development of liver failure).

With impaired renal function

Aquacitramone is contraindicated in renal failure.

For violations of liver function

In liver diseases, Aquacitramon should be used with caution.

Drug interactions

Aquacitramone enhances the effect of hypoglycemic agents, oral anticoagulants, steroid hormones, reserpine and heparin, as well as the side effects of non-steroidal anti-inflammatory drugs, non-narcotic analgesics, sulfonylurea derivatives, glucocorticosteroids and methotrexate.

The drug reduces the effectiveness of antihypertensive drugs, furosemide, spironolactone and anti-gout drugs that promote the excretion of uric acid.

Paracetamol increases chloramphenicol elimination time by 5 times.

Caffeine accelerates the absorption of ergotamine.

Aquacitramone is not recommended for use in combination with antiepileptic drugs, barbiturates, rifampicin, zidovudine and ethanol, since the risk of developing a hepatotoxic effect increases.

Analogs

Analogs of Aquacitramon are: Analgin-Quinine, Askofen-P, Benalgin, Brustan, Ibuklin, Kaffetin, Kofitsil-Plus, Nurofen Long, Padeviks, Pentabufen, Safiston, Santoperalgin, Sedal-M, Solpadein, Tempalginit, Tsimracomrin Citrapac, Excedrin, etc.

Terms and conditions of storage

Store at a temperature not exceeding 25 ° C in a dry, protected from light, out of reach of children.

Shelf life is 2 years.

Terms of dispensing from pharmacies

Available without a prescription.

Reviews about Aquatsitramon

According to patient reviews, Aquacitramone is an effective pain reliever that helps to quickly get rid of different types of pain. However, many consider the cost to be somewhat overpriced and indicate that they prefer cheaper drugs with a similar effect.

Price for Aquatsitramon in pharmacies

Depending on the region of sale and the pharmacy chain, the price for Akvatsitramon is 124-168 rubles. per package of 5 bags of 3 g.

Aquacitramon: prices in online pharmacies

Drug name Price Pharmacy

Aquacitramon granules for oral solution preparation 3 g 5 pcs. 135 RUB Buy

Maria Kulkes Medical journalist About the author

Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!