Troxerutin-MIC
Troxerutin-MIC: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. In case of impaired renal function
- 12. Drug interactions
- 13. Analogs
- 14. Terms and conditions of storage
- 15. Terms of dispensing from pharmacies
- 16. Reviews
- 17. Price in pharmacies
Latin name: Troxerutin-MIK
ATX code: C05CA04
Active ingredient: Troxerutin (Troxerutin)
Manufacturer: Unitary Enterprise "Minskintercaps" (Republic of Belarus)
Description and photo update: 2020-25-02
Prices in pharmacies: from 221 rubles.
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Troxerutin-MIC is a drug that has a venotonic and venoprotective effect; semi-synthetic bioflavonoid, a derivative of rutin.
Release form and composition
Dosage form - capsules: gelatinous, size No. 1, cylindrical, with yellow hemispherical ends; inside the capsules there is an odorless amorphous powder or a pre-pressed column of yellow powder, which is easily destroyed by a glass rod (in a cardboard box there are 5 packs of cell contour, containing 10 capsules each, and instructions for using Troxerutin-MIC).
Composition of 1 capsule:
- active substance: troxerutin - 200 or 300 mg;
- auxiliary components of 200 mg capsules: calcium stearate, lactose, potato starch;
- auxiliary components of 300 mg capsules: lactose, magnesium stearate;
- capsule shell: titanium dioxide, purified water, glycerol, gelatin, sodium lauryl sulfate, quinoline yellow dye (food additive E104); dye solar sunset yellow (food additive E110).
Pharmacological properties
Pharmacodynamics
Troxerutin is an angioprotective drug that acts primarily on veins and capillaries. After its application, the pores between endothelial cells are reduced by modifying the fibrous matrix located between the endothelial cells. The drug has anti-inflammatory properties, inhibits aggregation and increases the degree of deformability of erythrocytes.
Therapy in patients with chronic venous insufficiency is accompanied by a decrease in the severity of pain, edema, trophic disorders, seizures and varicose ulcers, as well as relief of symptoms associated with hemorrhoids (bleeding, itching and pain).
The substance has a beneficial effect on the resistance and permeability of the capillary walls, which leads to a slowdown in the development of diabetic retinopathy. Also, Troxerutin-MIC has an effect on the rheological properties of blood, which helps to prevent microthrombosis of retinal vessels.
Pharmacokinetics
The absorption of troxerutin after oral administration varies in the range from 10 to 15%. On average, after 2 hours after taking the capsules, its maximum concentration (C max) in the blood plasma is reached, the therapeutic level remains in it for 8 hours.
Troxerutin is metabolized in the liver, and 2 metabolites are formed. Excretion is mainly carried out by the kidneys and with bile (unchanged by 11%) within 24 hours.
Indications for use
- hematomas;
- phlebeurysm;
- vascular side effects of radiation therapy;
- post-traumatic edema;
- chronic venous insufficiency, accompanied by superficial thrombophlebitis, static heaviness in the legs, trophic skin lesions, leg ulcers, dermatitis, phlebothrombosis, post-thrombotic syndrome, hemorrhoids, retinopathy, leg ulcers, diabetic microangiopathy, periflebitis, hemorrhoids, including hemorrhoids flu, scarlet fever and measles;
- the period after surgical interventions on the veins (prevention of complications).
Contraindications
Absolute:
- peptic ulcer of the stomach and duodenum;
- exacerbation of chronic gastritis;
- I trimester of pregnancy;
- lactation period;
- age under 15 years (for Troxerutin-MIC 200 mg capsules);
- age under 18 years (for Troxerutin-MIC 300 mg capsules);
- established hypersensitivity to the components of the drug.
Relative (taking the drug requires special care and careful medical supervision): renal failure (long-term treatment); II and III trimester of pregnancy.
Troxerutin-MIC, instructions for use: method and dosage
Troxerutin-MIC capsules are intended for oral administration.
A single dose should be taken with meals and washed down with water (sufficient amount).
At the beginning of therapy, the dose of the drug is 1 capsule 3 times a day. As a maintenance treatment, 1-2 capsules are prescribed per day.
The duration of the drug intake is from 14 to 28 days.
In order to mitigate the unwanted vascular effects of radiation therapy, the drug is prescribed in higher doses.
The duration of the course of treatment should not exceed 2 months.
Side effects
During therapy with Troxerutin-MIC, in some cases, allergic reactions may develop in the form of a skin rash, headache, as well as erosive and ulcerative lesions of the gastrointestinal tract.
Overdose
Possible symptoms: flushing of the face, nausea, agitation, headache.
Therapy: gastric lavage, the appointment of activated carbon, symptomatic treatment (if necessary).
special instructions
It should be borne in mind that the expected therapeutic result can be achieved only through strict adherence to the doctor's instructions regarding the dosage of the drug and the duration of its use.
Troxerutin-MIC can be used as one of the components of complex treatment. In particular, for patients with conditions characterized by structural disturbances and increased vascular permeability (against the background of allergic reactions, influenza, measles and scarlet fever), it is prescribed in combination with ascorbic acid in order to enhance its therapeutic effect.
In case of severe renal impairment, a long course of taking capsules is not recommended.
Application during pregnancy and lactation
- I trimester of pregnancy / period of breastfeeding: the drug is contraindicated;
- II and III trimester of pregnancy: Troxerutin-MIC can be used only on strict indications in cases where the benefits of therapy outweigh the existing risk.
Pediatric use
Age restrictions for children and adolescents when prescribing the drug, depending on the dosage:
- Troxerutin-MIC 300 mg capsules: under 18 years of age;
- Troxerutin-MIC 200 mg capsules: under 15 years of age.
With impaired renal function
Long-term use of the drug for renal failure should be carried out with caution.
Drug interactions
Troxerutin, when combined with ascorbic acid, enhances its effect on the structure and permeability of the vascular wall.
Analogs
Analogs of Troxerutin-MIC are Phlebopress, Troxerutin DS, Troxerutin, Troxevenol, Troxerutin Sanofi, Troxevasin, Troxerutin VERTEX, Troxerutin Vramed, Troxerutin Velpharm, etc.
Terms and conditions of storage
Store at temperatures up to 25 ° C. Keep out of the reach of children.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Dispensed by prescription.
Reviews about Troxerutin-MIC
Basically, patients leave positive reviews about Troxerutin-MIC. The advantages most often include the budgetary cost of the drug and its high efficiency in edema and varicose veins.
The most significant disadvantages are considered negative side reactions.
Price for Troxerutin-MIC in pharmacies
The approximate price for Troxerutin-MIC 200 mg is 212 rubles. per pack of 50 pcs.
Troxerutin-MIC: prices in online pharmacies
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Drug name Price Pharmacy |
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Troxerutin-MIC 0.2 g capsule 50 pcs. 221 r Buy |
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Troxerutin-Mik capsules 200mg 50 pcs. 245 RUB Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
