Troxevasin Neo
Troxevasin Neo: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews
- 16. Price in pharmacies
Latin name: Troxevasin Neo
ATX code: C05CA54
Active ingredient: heparin sodium (heparin sodium), dexpanthenol (dexpanthenol), troxerutin (troxerutin)
Manufacturer: ACTAVIS GROUP (Iceland)
Description and photo update: 2018-22-10
Prices in pharmacies: from 261 rubles.
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Troxevasin Neo is a multicomponent drug for external use, which has a local venotonic, angioprotective, antithrombotic and regenerative effect.
Release form and composition
The dosage form of Troxevasin Neo is a gel for external use: a transparent or almost transparent yellowish-greenish-yellow mass (40 g each in aluminum / laminate tubes or 100 g each in laminated tubes; in a cardboard box 1 tube).
Composition for 1 g of gel:
- active substances: sodium heparin - 1.7 mg (equivalent to 300 ME); dexpanthenol - 50 mg; troxerutin - 20 mg;
- auxiliary components: propylene glycol, carbomer, methyl parahydroxybenzoate, trolamine, propyl parahydroxybenzoate, purified water.
Pharmacological properties
Pharmacodynamics
Troxevasin Neo is a gel for external use containing the following active components, the combination of which determines its therapeutic effect:
- heparin is a natural antithrombotic factor produced by the body that prevents blood clotting, a direct anticoagulant. Improving the fibrinolytic properties of blood, enhances local blood flow and prevents thrombus formation; has an anti-inflammatory effect; inhibiting the activity of hyaluronidase, promotes the restoration of connective tissue;
- dexpanthenol (provitamin B 5) - in the skin it is transformed into pantothenic acid, which is part of coenzyme A (KoA), which plays an important role in acetylation and oxidation reactions. Improves metabolic processes, promoting the regeneration of damaged tissues, and enhances the absorption of heparin;
- troxerutin is a flavonoid with an angioprotective effect with P-vitamin activity. It has venotonic, anti-inflammatory, decongestant, anticoagulant, venoprotective and antioxidant effects; reduces fragility and permeability of capillaries, thereby increasing their tone; helps to increase the density of the vascular wall; normalizes microcirculation and tissue trophism; reduces congestion.
Pharmacokinetics
When applied topically, the active substances of Troxevasin Neo gel are quickly absorbed by the skin.
Pharmacokinetic characteristics:
- heparin - accumulates in the upper layers of the skin and actively binds to its proteins; a small amount of heparin enters the systemic circulation, does not have a systemic effect, does not cause any changes in blood coagulation parameters; does not penetrate the placental barrier;
- dexpanthenol - penetrates into all layers of the skin, transforming into pantothenic acid; entering the systemic circulation binds to blood plasma proteins (mainly albumin and β-globulin); not metabolized by the body, excreted unchanged;
- troxerutin - after 30 minutes it penetrates into the dermis, and after 2-5 hours - into the subcutaneous tissue; the amount of a substance that penetrates the systemic circulation does not have a clinical effect.
Indications for use
- CVI (chronic venous insufficiency), manifested by swelling and pain in the legs; a feeling of fullness, heaviness, tiredness of the legs; telangiectasia (spider veins and reticulum); convulsions and paresthesias;
- varicose veins;
- periphlebitis;
- thrombophlebitis;
- varicose dermatitis;
- pains of a traumatic nature (bruises, sprains, trauma) and post-traumatic edema.
Contraindications
- open infected wound surfaces or wounds with abundant exudate at the site of application;
- age under 18;
- individual hypersensitivity to any component of the drug.
Instructions for use of Troxevasin Neo: method and dosage
Gel Troxevasin Neo is intended for external use. The drug is applied to the affected area with a thin layer, evenly distributed with light rubbing movements over the skin surface until it is completely absorbed.
Recommended dosage: 2 times a day, in the morning and evening.
If necessary, it is allowed to apply the gel under elastic bandages or stockings.
To a large extent, the success of drug therapy depends on the regularity of its use over an extended period of time. The recommended course of treatment is 2 to 3 weeks. The need for further therapy is determined by the attending physician.
It is advisable to take repeated courses 2-3 times a year.
To enhance the therapeutic effect, gel treatment is preferably combined with Troxevasin capsules.
Side effects
Possible negative effects due to the application of the gel are local hypersensitivity reactions: skin rash and itching.
Overdose
Due to the insignificant systemic absorption of the active ingredients of the gel, overdose is unlikely.
special instructions
Avoid contact of the gel on mucous membranes, open wounds and in the eyes.
Gel Troxevasin Neo is not used intravaginally and rectally, as well as in ophthalmology.
Influence on the ability to drive vehicles and use mechanisms
There were no negative effects on concentration of attention and speed of psychomotor reactions during the use of the gel.
Application during pregnancy and lactation
According to the instructions, Troxevasin Neo is allowed without restrictions to be used during pregnancy and during breastfeeding.
Pediatric use
The use of the gel for the treatment of children and adolescents under the age of 18 is contraindicated due to the lack of such experience and insufficient data on the safety and effectiveness of its use in this age category.
Drug interactions
No interaction of Troxevasin Neo gel with other medicinal substances / preparations was revealed.
Analogs
Analogues of Troxevasin Neo are Venolife, Dolobene, Venabos, Gepatrombin, Heparin ointment, Trombless Plus, etc.
Terms and conditions of storage
Store in a dry place at a temperature not exceeding 25 ° C. Keep out of the reach of children.
Shelf life is 2 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Troxevasin Neo
Patients who have used the gel leave mostly positive reviews about Troxevasin Neo. The drug is well tolerated, has a tonic, decongestant and analgesic effect. The gel is practically odorless and well absorbed, effective for bruises and bruises. Negative side effects are rarely described; in a few reviews it is mentioned that the gel dries the skin and does not help to remove heaviness in the legs. As disadvantages are also indicated the prohibition to apply the gel to damaged skin areas and the cost, which, according to some patients, "could be lower."
Medical specialists note the effectiveness of the drug in the treatment and prevention of varicose veins (the data were tested on a large number of patients), but warn that the results are noticeable by the end of the third week of continuous use. The most effective application of the gel in combination with Troxevasin capsules.
Price for Troxevasin Neo in pharmacies
The price of Troxevasin Neo is about 250 rubles. for a tube of gel weighing 40 g.
Troxevasin Neo: prices in online pharmacies
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Drug name Price Pharmacy |
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Troxevasin Neo gel for external use 40 g 1 pc. 261 r Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
