Ophthalmoferon
Oftalmoferon: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacodynamics and pharmacokinetics
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy
- 10. Application in children
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews
- 16. Price in pharmacies
Latin name: Oftalmoferon
ATX code: S01AD05
Active ingredient: Interferon alpha-2b human recombinant + Diphenhydramine (Interferon alpha-2b human recombinant + Diphenhydramine)
Manufacturer: Firn M (Russia)
Description and photo update: 2019-31-07
Prices in pharmacies: from 264 rubles.
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Oftalmoferon is an antiviral drug for topical use in ophthalmology, has antimicrobial, anti-inflammatory, local anesthetic, immunomodulatory, regenerating effect.
Release form and composition
Dosage form - eye drops (5 or 10 ml in polymeric dropper bottles, in a cardboard box 1 bottle).
Content of active ingredients in 1 ml drops:
- Interferon alpha-2a - 10,000 international units (IU);
- Diphenhydramine - 1 mg.
Pharmacodynamics and pharmacokinetics
Human recombinant interferon alfa-2b, which is part of Ophthalmoferon eye drops as an active ingredient, is an antiviral immunomodulatory antiproliferative compound. Its action is complemented by an antihistamine - diphenhydramine. The latter blocks H 1 -histamine receptors, eliminating allergy symptoms by reducing edema and itching in the conjunctival region.
With local application of the drug, manifestations of systemic absorption have not been registered. This is confirmed by clinical blood tests, during which it was revealed that the content of the active substances of eye drops in plasma is significantly less than the standard detection limit (for interferon alpha-2b, this figure is 1–2 IU in 1 ml). Thus, there are no clinical symptoms of systemic absorption of diphenhydramine and human interferon alfa-2b.
Indications for use
- Keratitis: adenoviral, herpetic (punctate, vesicular, treelike, cardiovascular);
- Conjunctivitis: enteroviral (hemorrhagic), herpetic, adenoviral;
- Stromal herpetic keratitis with or without corneal manifestation;
- Herpetic uveitis;
- Keratouveitis of herpetic genesis with and without expression;
- Keratoconjunctivitis of adenoviral and herpetic etiology.
Contraindications
Hypersensitivity to drug components.
Instructions for the use of Oftalmoferon: method and dosage
Ophthalmoferon eye drops are used by drip injection into the conjunctival sac of each eye.
Recommended dosage: in the acute stage of the disease - 1-2 drops 6-8 times a day, then as the inflammatory process decreases, the drug is instilled 2-3 times a day until the signs of the disease disappear completely.
Side effects
The development of undesirable effects during the use of the drug has not been established.
Overdose
At the moment, no cases of overdose have been identified.
special instructions
Treatment should be carried out in compliance with the rules of asepsis and antiseptics, do not allow the dropper to come into contact with any objects.
Application during pregnancy
According to the instructions, Ophthalmoferon during pregnancy can be used only after a thorough series of tests are performed to identify the reaction of the mother and fetus to the drug. It is advisable to prescribe a drug if the positive effect of treatment significantly outweighs the risk of complications in the fetus and future newborn.
Application in children
There is no age limit for the use of Ophthalmoferon eye drops. This is due to the fact that with local use (instillation into the conjunctiva), the concentration of the active substances of the drug in the bloodstream is so small that there are no side effects.
It is allowed to use the drug in newborns, since it has an antiviral and immunomodulatory effect, and it contains interferon. The drug eliminates itching and promotes the regeneration of damaged eye tissues, effectively coping with the inflammatory process. Before using the mother, it is recommended to consult an ophthalmologist, who, depending on the course of the disease and the age of the patient, will select an individual treatment regimen and the optimal dosage.
Drug interactions
Interaction with other drugs has not been established.
Analogs
Analogs of Oftalmoferon are: Aktipol, Poludan, Oftan-Idu.
Terms and conditions of storage
Keep out of the reach of children.
Store in a dark, dry place at a temperature of 2-8 ° C.
Shelf life is 2 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Oftalmoferon
According to reviews, the drug is quite effective in the treatment of a number of ophthalmic diseases. Comments on the drug are mostly positive, since it can be used in patients of both children and the elderly as an element of therapy for dry eye syndrome, conjunctivitis of various etiologies, as well as for prophylactic purposes.
Many parents note the safety of using Oftalmoferon for children and the absence of side effects such as itching and allergic reactions.
The price of Oftalmoferon in pharmacies
The price of Oftalmoferon (10 ml packaging) varies in the range of 270–350 rubles. It was possible to buy the drug in a 5 ml package for about 200 rubles, but at the moment it is not available in pharmacy chains.
Oftalmoferon: prices in online pharmacies
Drug name Price Pharmacy |
Ophthalmoferon 10000 IU / ml eye drops 10 ml 1 pc. 264 r Buy |
Ophthalmoferon eye drops 10000 IU / ml 10ml 310 RUB Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!