Maksar
Maksar: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews
- 16. Price in pharmacies
Latin name: Maksar
ATX code: A05C
Active ingredient: maakia Amur wood extract (maackiae amurensis ligni extract)
Producer: Obninsk Chemical and Pharmaceutical Company (Russia)
Description and photo update: 2018-23-10
Prices in pharmacies: from 999 rubles.
Buy
Maksar is a hepatoprotective herbal preparation.
Release form and composition
Maksar is produced in the form of film-coated tablets: yellow, biconvex (50 or 100 pieces in a dark glass jar, in a cardboard box 1 can; 50 or 100 pieces in a polymer can, in a cardboard box 1 can; 10 pcs. in blisters, in a cardboard box 5, 4, 3, 2 or 1 blister).
1 tablet contains:
- active substance: extract of Amur maakia wood - 0.06 g, with a total content of stilbenes and isoflavones not less than 19.8%;
- auxiliary components: microcrystalline cellulose, potato starch, dextrose monohydrate, magnesium stearate;
- composition of the film shell: colloidal silicon dioxide, hypromellose, titanium dioxide, talc, tropeolin-O dye.
Pharmacological properties
Maksar has a hepatoprotective, choleretic effect, helps to restore the disturbed histoarchitectonics of the liver, reduce the number of necrotized hepatocytes, and eliminate protein and fatty degeneration of the liver parenchyma. The therapeutic effect of the drug is determined by a complex of substances of dry extract from the wood of Amur Maakia, which have high biological activity. The most important of these are isoflavones such as maakiazin, formononetin, retusin, genistein, and stilbenes - piceatanol, resveratrol.
The mechanism of action of Maksar is aimed at inhibiting the lipid peroxidation reaction, improving the respiratory function of mitochondria, stabilizing the lysosomal membrane and inhibiting the release of necrosogenic hydrolases (including phospholipase A). Stimulating the processes of glucuronidation of bilirubin, oxidation and conjugation of xenobiotics, it helps to increase the excretory function of the liver, reduces hyperenzymemia of lactate dehydrogenase, aminotransferases, alkaline phosphatase.
The anti-necrotic and anti-inflammatory effect of the drug in chronic hepatitis is aimed at suppressing the synthesis of collagen and glycosaminoglycans, stimulated by lipid peroxidation products, and curbing the formation of fibrosis inside the hepatic lobules.
The choleretic effect of the drug is manifested in an increase in the rate of bile secretion and excretion of fatty acids, cholesterol and bilirubin into bile.
Indications for use
- chronic and acute forms of hepatitis;
- cirrhosis of the liver;
- fatty liver hepatosis;
- cholestasis syndrome.
Contraindications
- acute phase of gallstone disease;
- period of pregnancy;
- breast-feeding;
- age up to 18 years;
- individual intolerance to the components of the drug.
Instructions for use of Maksar: method and dosage
The tablets are taken orally, no later than 0.5 hours before meals.
Recommended dosage: 1 pc. 3 times a day, the duration of the course of treatment is 28 days.
Extension or repeated courses of therapy should be performed only on the recommendation of a doctor.
Side effects
Allergic reactions may develop while taking Maksar.
Overdose
Overdose symptoms have not been established.
special instructions
Influence on the ability to drive vehicles and complex mechanisms
According to the instructions, Maksar does not affect the patient's ability to drive vehicles and mechanisms.
Application during pregnancy and lactation
You can not prescribe the drug during gestation and when breastfeeding.
Pediatric use
The use of the drug is contraindicated in children under the age of 18.
Drug interactions
The interaction of Maksar when combined with other drugs has not been established.
Analogs
Analogs of Maksar are: Karsil, Ursodez, Geptral, Essentiale, Galstena, Ursosan.
Terms and conditions of storage
Keep out of the reach of children.
Store at a temperature of 8-25 ° C, protected from moisture and light.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Dispensed by prescription.
Reviews about Maxar
The few reviews about Maksar are positive. Patients point to the clinically proven therapeutic effect of the tablets when used to restore damaged liver cells. Treatment gives a long-term remission. Speaking about the advantages of the drug, everyone emphasizes the plant origin of the tablets, the absence of undesirable application reactions, and an affordable price. The shortage of an effective drug of domestic production in some regions makes patients lament over the need to replace it with expensive imported analogues.
Price for Maksar in pharmacies
The price of Maksar is unknown, since the drug is currently not available in the pharmacy chain.
Maksar: prices in online pharmacies
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Drug name Price Pharmacy |
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Maksar 60 mg film-coated tablets 50 pcs. 999 RUB Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
