Lugol's solution with glycerin
Latin name: Lugol solution with glycerin
ATX code: D08AG, R02AA20
Active ingredient: iodine + (potassium iodide + glycerol) [Iodide + (Potassium iodide + Glycerol)]
Manufacturer: CJSC "MosPharma" (CJSC "Moscow Pharmaceutical Factory") (Russia); JSC "Samaramedprom" (Russia); Flora Kavkaza OJSC (Russia); JSC "Tverskaya Pharmaceutical Factory" (Russia); JSC Kirovskaya Pharmaceutical Factory (Russia); CJSC "EKOlab" (Russia)
Description and photo update: 2019-08-10
Prices in pharmacies: from 9 rubles.
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Lugol's solution with glycerin is an antiseptic drug.
Release form and composition
Dosage form - solution for local application: red-brown syrupy, transparent liquid, with a specific smell of iodine (in a cardboard box 1 orange glass dropper bottle, 1 orange glass bottle or 1 brown glass bottle with a spray nozzle, containing 25, 30, 40, 50 or 100 g of solution, and instructions for the use of Lugol solution with glycerin; in a group carton of cardboard 36, 49 or 64 bottles of 25, 30, 40 or 50 g of solution or 16, 24 or 25 bottles of 100 g, complete with an equal number of instructions for medical use).
Composition of 100 g solution:
- active substance: iodine - 1 g;
- auxiliary components: glycerin (glycerol) - 85.5 g; potassium iodide - 2 g; purified water - 11.5 g.
Pharmacological properties
Pharmacodynamics
Lugol's actions of a solution with glycerin due to the components contained in its composition:
- iodine: has a local irritant and antimicrobial properties - destroys some spores of fungi, viruses, cysts, protozoa, gram-negative and gram-positive bacteria. It has a strong bactericidal effect, which manifests itself quickly (for the most part it is predetermined by molecular iodine). Reacts with dead proteins and microorganisms, which leads to a weakening of its bactericidal action;
- potassium iodide: helps to improve the dissolution of iodine ions in water;
- glycerol: has a local emollient effect.
Pharmacokinetics
In cases of contact with mucous membranes, 30% of the drug is converted into iodides, the rest into active iodine.
Orally taken iodine is rapidly absorbed and takes part in the synthesis of thyroid hormones. It is removed from the body mainly in the urine in the form of various compounds, to a lesser extent with feces and then, during lactation, it is excreted into breast milk.
Indications for use
Lugol's solution with glycerin is prescribed for the treatment of infectious and inflammatory pathologies of the mucous membranes of the mouth, larynx and pharynx - with pharyngitis, tonsillitis, laryngitis and angular stomatitis (cheilitis).
Contraindications
Absolute:
- pregnancy;
- period of breastfeeding;
- individual intolerance to the components of the drug.
Relative (Lugol's solution with glycerin is prescribed under medical supervision): dermatitis herpetiformis, hyperthyroidism, decompensated kidney and liver diseases, children under 12 years of age.
Lugol's solution with glycerin, instructions for use: method and dosage
Lugol's solution solution with glycerin is intended exclusively for topical use.
By means of a cotton swab dipped in the preparation and wound on a spatula or using the spray nozzle supplied in the kit, the solution is applied to the inflamed mucous membrane of the oral cavity, pharynx and larynx.
Side effects
During the period of Lugol's therapy with a solution with glycerin, allergic reactions may develop.
Prolonged use of the drug or the presence of hypersensitivity to iodine can lead to the occurrence of iodism. These include acne, urticaria-like skin rashes, rhinitis, burning throat, salivation, lacrimation, erythema, Quincke's edema, contact dermatitis, nausea, vomiting, bronchospasm.
Overdose
The main symptoms: irritation of the upper respiratory tract - bronchospasm, laryngospasm, burn. When ingested, hemoglobinuria, hemolysis, irritation of the mucous membranes of the gastrointestinal tract develop. Taking about 3 g of the drug can be fatal.
Therapy: gastric lavage with sodium bicarbonate solutions or 0.5% sodium thiosulfate solution, intravenous administration of sodium thiosulfate 30% (up to 300 ml) or other solutions with a slightly alkaline reaction.
special instructions
Patients with thyroid disorders should use iodine-containing preparations with caution.
The decomposition of active iodine is accelerated by sunlight and temperatures exceeding 40 ° C.
The drug should not be swallowed. It is important not to let it fall into your eyes. In case of accidental contact with the eyes, it is recommended to rinse them with sodium thiosulfate solution or plenty of water.
Application during pregnancy and lactation
Lugol's solution with glycerin for throat during pregnancy / lactation is not prescribed.
The drug belongs to category D - when used for more than 7 days, it is dangerous to the fetus.
Iodine passes into breast milk and can suppress the thyroid function of the newborn and infant.
With impaired renal function
Patients with decompensated pathologies of Lugol's kidneys are prescribed a solution with glycerin for the throat with caution.
For violations of liver function
With decompensated liver diseases, the drug is used under medical supervision.
Drug interactions
Possible interactions of Lugol's solution with glycerin with other drugs / substances:
- sodium thiosulfate: inactivates iodine;
- hydrogen peroxide, ammonia solutions, essential oils: pharmaceutically incompatible with the drug;
- alkaline or acidic environment, the presence of pus, fat, blood: reduce the antiseptic activity of the solution;
- drugs that suppress the function of the thyroid gland: in the case of simultaneous use with accidental oral administration of Lugol's solution with glycerin, their effectiveness is weakened;
- acetylsalicylic acid and other drugs that irritate the gastric mucosa: their irritating effect may increase.
Analogs
An analogue of Lugol's solution with glycerin is Lugol, Boric acid alcohol solution, Miramistin, Okomistin.
Terms and conditions of storage
Store in a place protected from light and moisture at temperatures up to 25 ° C. Keep out of the reach of children.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Lugol's solution with glycerin
According to reviews, Lugol's solution with glycerin is a safe, effective, affordable, fast-acting drug used in the treatment of throat diseases.
Among the disadvantages are the disgusting taste of the solution, the occurrence of discomfort and a burning sensation during its application and after use. Many people note that the drug is inconvenient to apply to the inflamed mucous membrane of the throat, pharynx and larynx.
Price for Lugol's solution with glycerin in pharmacies
The approximate price for Lugol's solution with glycerin is: in bottles of 25 g of solution - 10 rubles; in vials of 25 g with a spray nozzle - 69 rubles.
Lugol's solution with glycerin: prices in online pharmacies
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Drug name Price Pharmacy |
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Lugol's solution with glycerin solution for topical application 25 g 1 pc. RUB 9 Buy |
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Lugol's solution with glycerin solution for topical application 25 g 1 pc. 12 RUB Buy |
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Lugol's solution with glycerin solution for topical application 25 g 1 pc. 12 RUB Buy |
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Lugol's solution with glycerin solution for topical application 50 g 1 pc. RUB 40 Buy |
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Lugol's solution with glycerin solution for topical application 50 g 1 pc. RUB 49 Buy |
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Lugol's solution with glycerin solution for topical application with a spray nozzle 50 g 1 pc. RUB 54 Buy |
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Lugol's solution with glycerin solution for topical application 50 g 1 pc. RUB 67 Buy |
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Lugol's solution with glycerin for places. approx. spray bottle 50g RUB 76 Buy |
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Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
