Isoprinosine
Instructions for use:
- 1. Pharmacological action
- 2. Release form
- 3. Indications for use
- 4. Contraindications
- 5. Instructions for use
- 6. Side effects
- 7. Storage conditions
Prices in online pharmacies:
from 517 rub.
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Isoprinosine is a complex synthetic immunostimulating and antiviral drug used to treat diseases caused by herpes viruses.
It is widely used in pediatrics to improve immunity in chronic and protracted viral diseases.
pharmachologic effect
The active substance Isoprinosine has antiviral and immunostimulating activity. Reduces the clinical manifestations of viral diseases and blocks the multiplication of various viruses.
Isoprinosine also helps to accelerate recovery and increase the body's resistance to various herpeviruses (Epstein-Barr, Varicella-Zoster), measles viruses, mumps and others. When administered with other antiviral drugs (zidovudine and acyclovir), it enhances the effect of interferon.
According to reviews, Isoprinosine is usually well tolerated and approved for use in pediatrics.
Release form
Isoprinosine is produced in the form of white biconvex oblong tablets with an amine odor. Each tablet contains 500 mg of the active ingredient inosine pranobex. Excipients - wheat starch, mannitol, magnesium stearate, povidone. There are 10 tablets in a blister, 2, 3, 5 blisters in a cardboard box.
Isoprinosine analogs are also produced in the same doses.
Indications for the use of Isoprinosine
According to the instructions, Isoprinosine is prescribed with both a weakened and a normal immune system with:
- Infectious mononucleosis caused by the Epstein-Barr virus;
- Infections caused by the Herpes simplex virus 1-4 types (labial and genital herpes, herpetic keratitis);
- Corey;
- Viral bronchitis;
- Human papillomavirus infection, including papilloma of the vocal cords and larynx of fibrous type, warts, papillomavirus infection of the genitals in men and women;
- Equine encephalitis;
- Cytomegalovirus infection;
- Shingles;
- Influenza and lingering SARS;
- Acute and chronic viral hepatitis B and C;
- Chickenpox;
- Chronic infectious diseases of the respiratory and urinary systems;
- Subacute sclerosing panencephalitis;
- Molluscum contagiosum.
Also, Isoprinosine is quite effective in immunodeficiency states, and is prescribed during the recovery period after severe illnesses and in stressful situations for the prevention of infectious diseases.
Contraindications
According to the instructions, isoprinosine is contraindicated for:
- Urolithiasis;
- Arrhythmias;
- Chronic renal failure;
- Gout;
- Hypersensitivity to the components of Isoprinosine;
- The drug is not prescribed for children under 3 years of age (or with a body weight of less than 15 kg).
Instructions for the use of Isoprinosine
Isoprinosine is taken orally, after meals, washed down with a little water.
The dose of Isoprinosine according to the instructions is calculated the same for adults and children - 50 mg per 1 kg of body weight per day. The dose can be divided into 3-4 doses. Individually, the dose can be doubled in severe forms of infectious diseases, while it must be divided into 4-6 doses. The maximum daily dose of Isoprinosine for children is 50 mg per 1 kg of body weight, and for adults - 3-4 g per day.
The duration of treatment depends on the nature and course of the disease:
- In acute diseases in children and adults, the duration is from 5 to 14 days. Treatment should include the disappearance of clinical symptoms, and continued for another two days;
- In chronic (recurrent) diseases, treatment is prescribed in several courses of 5-10 days. The break between courses is 8 days;
- With maintenance therapy, you can use a maintenance dose of 0.5-1 g per day for a month.
In case of herpes infection, Isoprinosine is prescribed for children and adults for 5-10 days until the symptoms disappear completely. Then, for a month, supportive therapy is carried out to reduce the number of relapses, 1 tablet twice a day.
For adults with papillomavirus infection, the drug is prescribed 2 tablets 3 times a day. The dose of Isoprinosine for children is 1/2 tablet per 5 kg of body weight per day for 14-28 days. The same dose is prescribed for recurrent genital warts as monotherapy or with surgical treatment. Then, with an interval of a month, the course is repeated three times.
In case of cervical dysplasia associated with human papillomavirus, 2 tablets are taken 3 times a day for 10 days, after which another 2-3 courses are prescribed with an interval of two weeks.
Side effects
Isoprinosine is a fairly safe drug used in world medical practice since 1970.
According to reviews, Isoprinosine is well tolerated by adults and children. Sometimes itching, joint pain, headache, polyuria, dizziness, nausea, weakness, drowsiness or insomnia, exacerbation of gout may occur.
Sometimes, according to reviews, Isoprinosine as a side effect causes toxic hepatitis and kidney complications in children. Therefore, it is recommended to monitor the content of uric acid in the blood serum and in the urine after two weeks of using the drug, and also after a month from the beginning of the intake, to monitor the liver and kidney function. Such control must be carried out when using combination therapy with drugs that increase the level of uric acid and impair renal function.
It should be borne in mind that when used simultaneously with immunosuppressants, the effectiveness of Isoprinosine may decrease. The drug should not be taken in conjunction with immunosuppressants.
The use of Isoprinosine during pregnancy and during breastfeeding is not recommended due to the lack of clinical studies.
The analogs of Isoprinosine that are closest in chemical composition and therapeutic effect are Groprinosin and Inosin pranobex. These preparations also contain the active ingredient and dosage. The distinction between trade names depends on the drug manufacturers. These analogs of Isoprinosine can, if necessary, completely replace the drug.
Storage conditions
Isoprinosine is classified as List B drugs. Shelf life is 5 years.
Isoprinosine: prices in online pharmacies
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Drug name Price Pharmacy |
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Isoprinosine 500 mg tablets 20 pcs. RUB 517 Buy |
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Isoprinosine tablets 500mg 20 pcs. RUB 533 Buy |
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Isoprinosine 500 mg tablets 30 pcs. 824 RUB Buy |
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Isoprinosine 500mg tablets 30 pcs. Luzomedikament 944 RUB Buy |
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Isoprinosine 500 mg tablets 50 pcs. RUB 1505 Buy |
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Isoprinosine 500mg tablets 50 pcs. 1762 RUB Buy |
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
