Zalain - Instructions For Using Cream And Candles, Price, Analogues, Reviews

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Zalain - Instructions For Using Cream And Candles, Price, Analogues, Reviews
Zalain - Instructions For Using Cream And Candles, Price, Analogues, Reviews

Video: Zalain - Instructions For Using Cream And Candles, Price, Analogues, Reviews

Video: Zalain - Instructions For Using Cream And Candles, Price, Analogues, Reviews
Video: Zalain / Gynozalain: Sertaconazole.wmv 2024, November
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Zalain

Zalain: instructions for use and reviews

  1. 1. Release form and composition
  2. 2. Pharmacological properties
  3. 3. Indications for use
  4. 4. Contraindications
  5. 5. Method of application and dosage
  6. 6. Side effects
  7. 7. Overdose
  8. 8. Special instructions
  9. 9. Drug interactions
  10. 10. Analogs
  11. 11. Terms and conditions of storage
  12. 12. Terms of dispensing from pharmacies
  13. 13. Reviews
  14. 14. Price in pharmacies

Latin name: Zalain

ATX code: D01AC14

Active ingredient: sertaconazole nitrate (sertaconazole nitrate)

Manufacturer: Ferrer Internacional (Spain)

Description and photo update: 2019-20-08

Prices in pharmacies: from 350 rubles.

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Cream for external use Zalain
Cream for external use Zalain

Zalain is an antifungal drug for local and external use.

Release form and composition

Zalain is available in the following dosage forms:

  • Vaginal suppositories: oval, white, waxy (1 pc. In blisters, 1 blister in a cardboard box);
  • Cream for external use 2%: soft, white, with a slight odor of fat or odorless (20 g each in aluminum tubes, 1 tube each in a cardboard box).

1 suppository contains:

  • Active substance: sertaconazole nitrate - 0.3 g;
  • Auxiliary components: suppository - 1.305 g, witepsol - 1.305 g, anhydrous colloidal silicon dioxide - 0.09 g.

The composition of 100 g of cream for external use includes:

  • Active substance: sertaconazole nitrate - 2 g;
  • Auxiliary components: methyl p-hydroxybenzoate - 0.1 g, polyethylene glycol and ethylene glycol palmitostearate - 20 g, saturated polyglycolized glycerides - 5 g, paraffin oil - 8 g, glycerol isostearate - 2 g, sorbic acid - 0.1 g, purified water - up to 100 g.

Pharmacological properties

Pharmacodynamics

Sertaconazole belongs to benzothiophene and imidazole derivatives and is characterized by a wide spectrum of action against pathogens of infectious diseases of the skin and mucous membranes (gram-positive strains of streptococci and staphylococci), dermatophytes (Microsporum and Trichophyton) and pathogenic fungi (Pityrosporum spp., Cand. Spp., Candida albicans). The drug exhibits fungicidal and fungistatic effects when used in recommended doses.

The mechanism of action of sertaconazole is to increase the permeability of the cell membrane, which causes lysis of the fungal cell, and suppression of the synthesis of ergosterol - the main sterol that is part of the membranes of yeast and fungi.

Pharmacokinetics

When applied topically, sertaconazole is not detected in blood and urine. There is no absorption after intravaginal administration.

Indications for use

According to the instructions, Zalain in the form of suppositories is prescribed for the local treatment of infections of the vaginal mucosa caused by fungi of the genus Candida (candidal vulvovaginitis).

Zalain cream is prescribed for candidiasis, pityriasis versicolor, superficial mycoses of the skin, including mycoses of the beard, trunk, legs, feet and hands.

Contraindications

Zalain is contraindicated for use in case of hypersensitivity to the components of the drug, as well as to benzothiphene and imidazole derivatives.

The use of the drug by lactating and pregnant women is possible only in cases where the intended benefits to the health of the mother are higher than the possible risk to the child or fetus.

Breastfeeding women should not apply the cream to their breasts.

Instructions for the use of Zalain: method and dosage

The drug in the form of suppositories is used once, before bedtime.

1 vaginal suppository should be inserted in the supine position deep into the vagina. If the clinical symptoms persist after 7 days, the drug can be reused. Before the introduction of the drug, you need to wash the external genitalia using soap (alkaline or neutral).

Zalain in the form of a cream is applied in a uniform thin layer on the affected skin 2 times a day, capturing about 1 cm of the healthy skin surface. The duration of therapy is determined by the etiology of the pathogen and the localization of the infection. As a rule, the symptoms of the disease disappear after 14-28 days. The recommended duration of the drug use is 1 month.

Side effects

During the use of Zalain suppositories, in rare cases, it is possible to develop a burning sensation, itching in the vagina, which usually go away on their own without additional therapy and do not require discontinuation of the drug. These side effects are classic for topical preparations and reflect the effectiveness of their use. Also, during therapy, allergic reactions may develop.

When applying the cream, local reactions may occur, manifested in the form of contact dermatitis. It is also possible to develop rapidly passing erythematous reactions, which do not require discontinuation of the drug.

Overdose

Since the drug is used externally and intravaginally, overdose is considered unlikely. In case of accidental oral administration of sertaconazole by mouth, it is necessary to rinse the stomach and consult a specialist who will prescribe symptomatic therapy.

special instructions

Suppositories can be used during menstruation.

With the development of a simultaneous infection of the labia and adjacent areas (candidal vulvitis), it is additionally recommended to carry out local treatment with Zalain in the form of a cream.

The risk of damage to barrier contraception (diaphragm or condom rupture) increases when used concurrently with Zalain.

During therapy, you should refrain from sexual intercourse. To prevent the development of urogenital reinfection, simultaneous treatment of the sexual partner is recommended.

Zalain cream is not used in ophthalmic practice. During therapy, the use of acidic detergents is not recommended (the multiplication of Candida spp. Fungi increases in an acidic environment).

Influence on the ability to drive vehicles and complex mechanisms

The use of Zalain does not affect the ability to engage in potentially hazardous activities that require increased attention and immediate psychomotor reactions (driving, etc.).

Drug interactions

With the simultaneous use of suppositories Zalain with local contraceptives, it is possible to weaken the spermicidal action of the latter.

Analogs

Zalain's analogues are: Sertaconazole, Optiginal, Sertamikol, Clotrimazole-Akrikhin, Candide, Dermazole, etc.

Terms and conditions of storage

Keep out of the reach of children.

Shelf life - 3 years at a temperature:

  • Vaginal suppositories - up to 30 ° C;
  • Topical cream - up to 25 ° C.

Terms of dispensing from pharmacies

Available without a prescription.

Reviews about Zalain

Reviews of Zalain in the form of a cream are quite favorable. Patients highly rate the safety, efficacy and duration of the drug compared to similar topical drugs. Many of them recommend Zalain to friends who have been diagnosed with the same infectious diseases.

Reviews of Zalain candles are also positive. There are often references to a decrease in the severity of symptoms of candidiasis after the introduction of one suppository. Some women advise using the drug in this form during pregnancy, given its high safety and a decrease in the recurrence rate of an infectious disease. However, antifungal therapy in each individual case should be selected by the doctor individually.

Price for Zalain in pharmacies

The approximate price for Zalain in the form of a cream is 466–556 rubles, and in the form of vaginal suppositories - 502–615 rubles.

Zalain: prices in online pharmacies

Drug name

Price

Pharmacy

Zalain 2% cream for external use 20 g 1 pc.

RUB 350

Buy

Zalain 300 mg vaginal suppositories 1 pc.

RUB 400

Buy

Zalain vaginal suppositories. 300mg

RUB 518

Buy

Zalain cream 2% 20g

RUB 524

Buy

Anna Kozlova
Anna Kozlova

Anna Kozlova Medical journalist About the author

Education: Rostov State Medical University, specialty "General Medicine".

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!

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