Deprim
Deprim: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Drug interactions
- 10. Analogs
- 11. Terms and conditions of storage
- 12. Terms of dispensing from pharmacies
- 13. Reviews
- 14. Price in pharmacies
Latin name: Deprim
ATX code: N06AX
Active ingredient: St. John's wort herb extract (extractum herbae Hyperici perforati)
Manufacturer: Lek, Slovenia; Sandoz dd, Slovenia
Description and photo update: 2019-13-08
Deprim is a herbal antidepressant.
Release form and composition
Deprim is produced in the form of coated tablets: biconvex, round, green (in blisters of 10 pcs., From 3 to 6 blisters in a cardboard box).
The composition of 1 tablet includes:
- Active ingredient: St. John's wort (dry standardized extract) - 60 mg (including hypericin (total) - 0.3 mg);
- Auxiliary components: magnesium stearate, lactose, talc, microcrystalline cellulose, colloidal silicon dioxide.
Shell composition: carnauba wax, polyethylene glycol, hydroxypropyl methylcellulose, talc, green and blue glaze, titanium dioxide (E171).
Pharmacological properties
Deprim is a herbal medicine with antidepressant and anxiolytic effects. Its active ingredient - extract of the herb St. John's wort - contains flavonoids, pseudohypericin, hypericin, hyperforin, which improve the functional state of the autonomic and central nervous system. Deprim improves mood and provides greater physical and mental activity.
Pharmacodynamics
The pharmacodynamics of Deprim is currently not well understood.
Pharmacokinetics
There is no information on the pharmacokinetics of the drug.
Indications for use
- Depressive states of moderate and mild severity, accompanied by a feeling of anxiety (including conditions associated with climacteric syndrome);
- Increased sensitivity to weather changes;
- Decreased mood.
Contraindications
- Severe depression;
- Age up to 6 years;
- Hypersensitivity to drug components.
For nursing and pregnant women, Deprim can only be taken if the expected benefit to the mother is higher than the potential risk to the fetus or child.
Instructions for the use of Deprim: method and dosage
Deprim should be taken orally with water.
Children from 12 years old and adults are usually prescribed 1 tablet 3 times a day (regularly at the same time). For children 6-12 years old, the drug can be taken in 1-2 tablets (in the morning and evening) under medical supervision.
The therapeutic effect appears 10-14 days after the start of therapy. The optimal effect of taking Deprim regularly is usually achieved within a few weeks.
If a dose is missed, it must be taken as soon as possible. You should not take an additional dose to compensate for the missed dose.
Side effects
During therapy, the development of disorders from some body systems is possible:
- Central nervous system: restlessness, feeling tired;
- Digestive system: vomiting, nausea, constipation;
- Dermatological reactions: photosensitivity (in combination with sunbathing in patients with hypersensitivity to sunlight);
- Allergic reactions: itching, flushing of the skin.
Overdose
Acute intoxication with Deprim in humans has not been registered. Signs of an overdose include drowsiness, lethargy, general weakness, and a greater severity of side effects depending on the dose taken. There are reports of confusion and the development of seizures after taking a dose of Deprim not exceeding 4.5 g daily for 2 weeks and taking an additional 15 g of the drug immediately before admission to the hospital. With significant overdoses, phototoxic reactions sometimes develop.
In this case, the drug is canceled and activated carbon is prescribed. It is also recommended to avoid exposure to the sun and UV radiation for 1-2 weeks. Outdoor activities should be limited as much as possible and clothing and / or skin protection should be used.
special instructions
If there is no therapeutic effect within 1-1.5 months from the start of treatment, you need to interrupt the reception of Deprim and consult your doctor.
Patients taking the drug are advised to avoid exposure to the sun and UV radiation (including tanning beds), and to refrain from drinking alcohol.
Influence on the ability to drive vehicles and complex mechanisms
There is no reliable information on the effect of Deprim on the ability to drive vehicles or perform complex types of work associated with increased concentration of attention and speed of psychomotor reactions.
Drug interactions
According to the instructions, Deprim should be taken with caution along with anticonvulsants, antidepressants (serotonin reuptake inhibitors), monoamine oxidase inhibitors, tricyclic antidepressants, anti-migraine drugs (tryptans), cardiac glycosides (including digoxin), oral hormonal drugs, contraceptives, contraceptives, contraceptives, cyclosporine.
When used together, Deprim can enhance the effect of opioid analgesics and general anesthetics.
Analogs
Deprim's analogs are: Alventa, Gerbion Hypericum, Gelarium Hypericum, Hyperflav, Deprivit, Venlift, Venlaxor, Velaksin, Life 600, Life 900, Mirtel, Neuroplant, St. John's wort.
Terms and conditions of storage
Keep out of reach of children at temperatures up to 25 ° C.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Deprim
Among doctors, there are mixed reviews about Deprim. Many patients self-medicate, taking the drug without consulting a specialist. This often led to an aggravation of the symptoms of the disease, as a result of which it was necessary to switch to drugs with a more intense effect. Doctors believe that St. John's wort extract may be effective for unstable moods, as well as mild apathy and depression.
Patients respond positively to Deprim. It is taken for seasonal mood swings and anxiety associated with significant changes in life or the loss of loved ones. It is recommended to apply the product regularly over a long period of time. Side effects are rare when taking Deprim. To avoid them, some patients prefer to change the treatment regimen, taking pills not in the morning or afternoon, but at night.
The price of Deprim in pharmacies
The approximate price for Deprim in pharmacy chains is 210–261 rubles (for a package of 30 tablets).
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
