Grammidin with neo anesthetic
Latin name: Grammidin with anesthetic neo
ATX code: R02A
Active ingredients: gramicidin C (Gramicidin S) + oxybuprocaine (Oxybuprocaine) + cetylpyridinium chloride (Cetylpyridinium chloride)
Manufacturer: JSC "Valenta Pharmaceuticals" (Russia)
Description and photo update: 2020-15-07
Prices in pharmacies: from 257 rubles.
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Grammidin with anesthetic neo - a drug of antimicrobial and local anesthetic action for local use in the treatment of diseases of the oral cavity and throat.
Release form and composition
Dosage form - tablets for resorption: round, biconvex, white, on one side there is an inscription GR (6 pieces in a blister contour packaging, in a cardboard box 2, 3 or 4 packs; 9 pcs. In a blister contour packaging, in a box of cardboard 2 packages and instructions for the use of Grammidin with anesthetic neo).
Composition for 1 tablet:
- active ingredients: gramicidin C dihydrochloride - 3.2 mg (corresponds to the content of gramicidin C - 3 mg); cetylpyridinium chloride monohydrate - 1.05 mg (corresponds to the content of cetylpyridinium chloride - 1 mg); oxybuprocaine hydrochloride - 0.2 mg;
- auxiliary ingredients: sorbitol - 1065.55 mg; colloidal silicon dioxide - 5 mg; talc - 60 mg; mint flavor - 25 mg; magnesium stearate - 25 mg; potassium acesulfame - 15 mg.
Pharmacological properties
Pharmacodynamics
Grammidin with neo anesthetic is a unique combination drug effective in the treatment of infectious and inflammatory diseases localized in the mouth and throat.
The preparation contains as active substances: gramicidin C - an antibiotic of the tyrothricin group; oxybuprocaine - a local anesthetic; cetylpyridinium chloride is an antiseptic.
The mechanism of action of Grammidin with the neo anesthetic is due to the pharmacological activity of its main components:
- gramicidin C: increases the permeability of the cytoplasmic membrane of the microbe cell, disrupting its resistance and leading to death. It has a pronounced antimicrobial activity against pathogenic microflora of the oral cavity and throat;
- oxybuprocaine: has a local anesthetic effect on the mucous membrane of the mouth and throat. Reversibly blocks the propagation and conduction of nerve impulses by the axons of nerve cells;
- cetylpyridinium chloride: has an antimicrobial effect, due to which it inhibits growth and suppresses the reproduction of causative agents of infectious diseases of the oral cavity.
Grammidin with neo anesthetic has an analgesic effect, reduces inflammation, and exhibits antimicrobial activity. When resorbed, the tablets facilitate swallowing, soften perspiration and relieve sore throat, increase the secretion of the salivary glands, as a result of which the abundant secretion of saliva in the oral cavity enhances its mechanical cleansing from pathogens.
Pharmacokinetics
When applied topically, the agent is practically not absorbed in the digestive tract and has no systemic effect.
Indications for use
Grammidin with neo anesthetic is used to treat such infectious and inflammatory diseases of the oral cavity and throat as tonsillitis, tonsillitis, acute pharyngitis, stomatitis, periodontal disease, gingivitis.
Contraindications
The drug is contraindicated for women in the first trimester of pregnancy, children under four years of age and patients with established hypersensitivity to any of its components.
Grammidin with neo anesthetic, instructions for use: method and dosage
Grammidin tablets with neo anesthetic are intended to be absorbed in the mouth. They cannot be chewed or swallowed.
The drug is used 1–2 hours before or after the same period of time after eating or any drinks.
Recommended dosage regimen:
- children aged 4-12 years: one tablet 1-2 times a day;
- children over 12 years of age and adult patients: one tablet 3-4 times a day.
Side effects
The use of Grammidin with the neo anesthetic in predisposed patients, in some cases, can cause hypersensitivity reactions to its constituent components. A transient loss of tongue sensitivity is also possible.
Overdose
There is no information on overdose cases.
special instructions
If there is no effect from using the drug within 1 week, it is recommended to consult a specialist.
Application during pregnancy and lactation
It is contraindicated to use Grammidin tablets with neo anesthetic in the first trimester of pregnancy.
It is recommended to stop breastfeeding while using the drug.
Pediatric use
In pediatrics, Grammidin with neo anesthetic is not prescribed for the treatment of children under four years of age.
Drug interactions
With simultaneous use, the drug enhances the effect of other local and systemic antibacterial agents.
Analogs
Analogs of Grammidin with anesthetic neo are Anti-Angin Formula, Hexoral Tabs, Doritricin, Septalor, Novosept Forte, Stopangin 2A, Strepsils Express, Teraflu LAR, Rinza Lorsept Anesthetics, etc.
Terms and conditions of storage
Store at a temperature of 25 ° C in a place protected from light. Keep out of the reach of children.
Shelf life is 2 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Grammidin with anesthetic neo
Most patients who have used the drug for sore throat or dental problems leave positive reviews about Grammidin with neo anesthetic. They argue that the resorption of tablets effectively relieves pain, and due to the content of antimicrobial and antiseptic components, it accelerates recovery.
As disadvantages, the inconvenient dosing regimen is most often noted, namely the fact that the drug must be used strictly between meals. Some people call it high cost.
Price for Grammidin with neo anesthetic in pharmacies
The approximate price of Grammidin with neo anesthetic, lozenges (3 mg + 0.2 mg + 1 mg), for a package containing 18 pieces, can range from 265 to 338 rubles.
Grammidin with neo anesthetic: prices in online pharmacies
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Drug name Price Pharmacy |
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Grammidin with neo anesthetic 3 mg + 0.2 mg + 1 mg lozenges 18 pcs. 257 r Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
