Amintax
Amintax: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. In case of impaired renal function
- 12. For violations of liver function
- 13. Drug interactions
- 14. Analogs
- 15. Terms and conditions of storage
- 16. Terms of dispensing from pharmacies
- 17. Reviews
- 18. Price in pharmacies
Latin name: Amintax
ATX code: G01AA51
Active ingredient: nystatin (Nystatin), neomycin (Neomycin), polymyxin B (Polymyxin B)
Producer: Altpharm LLC (Russia)
Description and photo update: 2019-10-07
Prices in pharmacies: from 329 rubles.
Buy
Amintax is a combined antibacterial drug for use in gynecology.
Release form and composition
Dosage form - vaginal suppositories: torpedo-shaped, yellow, possibly the presence of a funnel-shaped depression and / or an air rod (5 pcs. In cell contour packs, 2 packs in a cardboard box together with instructions for the use of Amintax).
Composition of 1 suppository:
- active ingredients: nystatin - 100,000 ME (International units), neomycin - 35,000 ME, polymyxin B - 35,000 ME;
- excipients: macrogol 400 and macrogol 1500 (in a ratio of 5:95) - until a suppository weighing 2400 mg is obtained.
Pharmacological properties
Pharmacodynamics
Amintax is a combined preparation, the effect of which is due to the properties of active substances:
- nystatin is an antifungal agent, an antibiotic of the polyene group, which has a fungicidal effect on pathogenic fungi, especially yeast-like of the genus Candida albicans, Histoplasma and Cryptococcus;
- neomycin and polymyxin B are antibiotics (aminoglycoside and polypeptide, respectively) that are active against many gram-positive (including corynebacteria and Staphylococcus aureus) and gram-negative (Escherichia coli, Enterobacter aerogenes, Enterococcus faecium, Klebsiella pneumgarisium, Protein influenzae, Ureaplasma urealyticum) microorganisms.
The drug also improves trophic processes in the vaginal mucosa.
Anaerobic bacteria and Streptococcus spp. Are insensitive to the action of Amintax.
Pharmacokinetics
With intravaginal use of the drug, the active substances are quickly distributed over the vaginal mucosa, practically not absorbed, and have a local bactericidal and fungicidal effect.
Indications for use
- treatment of infectious and inflammatory diseases caused by sensitive microorganisms: fungal, nonspecific and mixed vaginitis, cervicovaginitis and vulvovaginitis;
- preoperative prevention of infectious complications during gynecological interventions: intrauterine diagnostic procedures, diathermocoagulation of the cervix, childbirth.
Contraindications
Absolute:
- I trimester of pregnancy;
- lactation;
- hypersensitivity to any component of Amintax.
With caution, if the benefit to the mother from the forthcoming treatment outweighs the potential risk to the fetus, the drug is prescribed in the II and III trimesters of pregnancy.
Amintax, instructions for use: method and dosage
Amintax suppositories are intended for intravaginal use.
Suppositories should be administered in 1 pc. deep into the vagina, lying on your back, before going to bed. The duration of the treatment course is 12 days, the preventive course is 6 days.
If you miss the next appointment, you do not need to double the dose, you must continue the treatment as usual.
Side effects
- local reactions: itching, burning, irritation in the vagina;
- allergic reactions, including allergic contact eczema.
In the case of long-term treatment, there is a possibility of manifestation of systemic side effects inherent in neomycin.
Overdose
Considering the local method of application of Amintax, an overdose is unlikely. If the suppository is accidentally taken by mouth, the likelihood of developing systemic effects (nephro- and ototoxicity) is not excluded. With continued treatment, the risk of allergic contact eczema increases.
Therapy for the developed disorders is symptomatic.
special instructions
Amintax is prescribed after taking a smear and conducting a bacteriological analysis.
If after the end of the course of therapy there is no improvement, the existing symptoms worsen or new ones appear, you should immediately consult a doctor. If clinical signs of infection persist, a repeated microbiological examination is indicated to confirm the diagnosis.
The recommended duration of treatment should not be exceeded in order to prevent the formation of resistance of individual pathogens and to avoid the risk of reinfection.
It is not required to interrupt the course during menstruation, however, it is necessary to refrain from using vaginal tampons.
In case of local intolerance to Amintax, the development of allergic or other side reactions, you should stop using the drug and consult a doctor.
During the period of treatment, it is recommended to refrain from sexual intercourse. Latex products (including diaphragms) should not be used as there is a risk of rupture.
Influence on the ability to drive vehicles and complex mechanisms
The components included in Amintax do not affect the speed of psychomotor reactions and the ability to concentrate.
Application during pregnancy and lactation
In the first trimester of pregnancy, the use of vaginal suppositories Amintax is contraindicated. In the II and III trimesters, the drug can be prescribed only after a thorough assessment of the expected benefits and possible risks.
During lactation, drug treatment is contraindicated. In cases of absolute need for a course of therapy, women are advised to stop breastfeeding.
Pediatric use
Information not provided by the manufacturer.
With impaired renal function
Patients with renal insufficiency should consult a doctor before starting treatment.
For violations of liver function
There is no information indicating the need to change the dosage regimen of Amintax in case of functional liver disorders.
Drug interactions
You should not use spermicides during the treatment period, since they can reduce the effectiveness of the drug.
The drug interaction of Amintax with other drugs has not been studied.
Analogs
Amintax analogs are: Vilimiksin, Clindacin B Prolong, Polygynax, Polygynax Virgo.
Terms and conditions of storage
Store at a temperature not exceeding 25 ° C out of reach of children.
Shelf life is 2 years.
Terms of dispensing from pharmacies
Dispensed by prescription.
Reviews about Amintax
Patients leave mostly positive reviews about Amintax, noting that the drug is effective for various gynecological diseases caused by sensitive microorganisms, and it is also cheaper than many analogues.
At the same time, there are reports where women complain of the development of severe side effects (severe itching and burning), because of which they had to interrupt the course of treatment.
Price for Amintax in pharmacies
Depending on the region of sale and the pharmacy chain, the price for Amintax can be 410–525 rubles. for a pack of 10 vaginal suppositories.
Amintax: prices in online pharmacies
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Drug name Price Pharmacy |
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Amintax 35000 IU + 100000 IU + 35000 IU vaginal suppositories 10 pcs. 329 r Buy |
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Amintax vaginal suppositories. 3500ME + 100000ME + 35000ME 10 pcs. 477 r Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
