VIANVAK
VIANVAK: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews
- 16. Price in pharmacies
Latin name: Vianvac
ATX code: J07AP03
Active ingredient: Vi-antigen (Virulence antigen)
Manufacturer: FGBNU "FNTSIRIP im. M. P. Chumakov RAS "(Russia)
Description and photo updated: 2019-14-05
VIANVAC (Typhoid V-Polysaccharide Vaccine) is a vaccine for the prevention of typhoid fever.
Release form and composition
The drug is produced in the form of a solution for subcutaneous (subcutaneous) administration: a clear or slightly opalescent colorless liquid [0.5 ml (1 dose) in an ampoule, 5 or 10 ampoules in a blister strip or in a cardboard box, or 10 ampoules in a cardboard snake in a carton box together with instructions for using VIANVAC, or 500 ampoules in a cardboard box - in-bulk; 10 ml (20 doses) in a vial, 5 or 100 vials in a cardboard box; 18,000 ml (36,000 doses) in a Flexboy container, 1 container in a foam thermal container].
1 dose of solution (0.5 ml) contains:
- active substance: Vi-antigen - 0.025 mg;
- additional components: sodium phosphate monobasic, sodium phosphate disubstituted, sodium chloride, phenol, water for injection.
Pharmacological properties
Pharmacodynamics
VIANVAC is a solution of Vi-antigen - a capsular polysaccharide obtained from the culture supernatant of Salmonella typhi strain Tu-2 No. 4446 and purified using enzymatic and physicochemical methods.
As a result of the introduction of the drug, vaccinated specific Vi-antibodies appear in the blood quickly and intensively, which after 7-14 days ensure the body's immunity to infection, which lasts for at least three years.
Indications for use
VIANVAC vaccine is intended for the prevention of typhoid fever in children aged 3 years and older and adults.
Priority vaccination is subject to:
- population living in areas characterized by a high incidence of typhoid fever;
- population living in areas prone to chronic waterborne typhoid epidemics;
- persons whose field of activity is related to living cultures of typhoid pathogens;
- persons working in the field of public amenities (servicing sewer networks, equipment and structures, as well as those employed at enterprises for the sanitary cleaning of populated areas - collection, transportation and disposal of household waste);
- persons traveling to regions and countries hyperendemic for typhoid fever, as well as contacts in the outbreaks according to epidemiological indications.
According to epidemic indications, vaccinations are required when there is a danger of an epidemic / outbreak (serious accidents at the water supply and / or sewerage network, natural disasters), to persons contacting in outbreaks for epidemic indications, as well as during an epidemic.
Contraindications
- acute forms of infectious and non-infectious lesions, exacerbation of chronic diseases [vaccinations should be carried out 1 month after recovery (remission)];
- severe and unusual reactions caused by the previous administration of the VIANVAC vaccine;
- children under 3 years old;
- period of pregnancy.
In order to establish contraindications, the doctor / paramedic on the day of VIANVACA vaccination must conduct a survey and examination of the patient receiving the vaccine, including with the obligatory measurement of body temperature. If necessary, appoint an appropriate laboratory examination.
VIANVAC, instructions for use: method and dosage
VIANVAC is administered subcutaneously, vaccinations are carried out once.
The solution should be injected into the outer surface of the upper third of the shoulder. For patients of all ages, a single inoculation dose is 0.5 ml.
According to indications, revaccinations are performed every 3 years.
After opening the ampoule, the solution should be used immediately. It is necessary to open the ampoule and carry out the procedure for administering the vaccine with strict adherence to the rules of asepsis and antiseptics.
If the ampoule is damaged or labeled, the vaccine is not suitable for use. You can also not use the drug in the event of a change in its physical properties, improper storage or an expired shelf life.
The VIANVAC vaccination carried out is registered in the established registration forms, which indicate the name and dose of the drug, the date of vaccination, the batch number and side effects caused by the vaccination, if any.
Side effects
Reactions to the introduction of the drug are recorded quite rarely and are mild. These effects can be observed during the first 24 hours after immunization in the form of soreness and redness at the injection site, as well as headache and a slight increase in temperature - less than 37.6 ° C during the first 24-48 hours in 3-5% of cases.
Overdose
Cases of drug overdose have not been registered.
special instructions
VIANVAC, like any other vaccine, may not provide 100% protection against disease in all vaccinated patients.
Influence on the ability to drive vehicles and complex mechanisms
There are no data on the negative effect of the drug on the ability to drive a car and control complex equipment.
Application during pregnancy and lactation
The drug is not used during pregnancy.
There is no information on the use of the vaccine during breastfeeding.
Pediatric use
Vaccination can be carried out for children from 3 years old.
Drug interactions
VIANVAC and inactivated vaccines of the national vaccination calendar can be injected with different syringes in different areas of the body at the same time or with an interval of 30 days.
Analogs
The analogues of VIANVAK are Tifivak, Tifim Vi.
Terms and conditions of storage
Keep out of the reach of children. Avoid freezing.
Store at 2–8 ° С. It is allowed to transport the vaccine at a temperature of 2–25 ° С (transportation is allowed at temperatures up to + 35 ° С, but for a period not exceeding 2 weeks).
The shelf life is 3 years.
Terms of dispensing from pharmacies
For medical and sanitary facilities.
Reviews about VIANVAK
There are currently no reviews on VIANVAK left by patients on medical websites, by which it would be possible to realistically assess its effectiveness and disadvantages.
Price for VIANVAC in pharmacies
The price of VIANVAC, a solution for subcutaneous administration, can be 5410 rubles. per package containing 10 ampoules of 0.5 ml (1 dose).
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
