Antagonism I (Substances) - Glossary Of Medical Terms

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Antagonism I (Substances) - Glossary Of Medical Terms
Antagonism I (Substances) - Glossary Of Medical Terms

Video: Antagonism I (Substances) - Glossary Of Medical Terms

Video: Antagonism I (Substances) - Glossary Of Medical Terms
Video: Applied Pharmacology 8, Terminology 2024, November
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Antagonism I (substance antagonism)

Antagonism I (antagonism of substances) (Greek antagonisma - rivalry, struggle) is a type of interaction in the body of substances (vitamins, amino acids, medicinal substances), characterized by the fact that one of them weakens the effect of the other.

The following types of antagonism of substances are distinguished:

  • Absolute - the effect of the simultaneous action of substances is less than the effect of each of them separately;
  • Bilateral - either of the two substances removes or weakens the action of the other;
  • Competitive - substances interact with the same cell receptors (it is reversible);
  • Non-competitive - direct antagonism, characterized by the fact that one of the interacting substances acts on the receptor outside its active center;
  • Indirect (synonym: indirect antagonism) - the action of substances is directed to various elements of cells;
  • Non-equilibrium - one of the substances irreversibly interacts with receptors;
  • One-sided - the action of one substance removes the action of another, but not vice versa;
  • Relative - the effect of the simultaneous action of substances is greater than the individual effects of each of them, but less than the summation of the effects of the same substances acting separately;
  • Direct - the action of substances is directed to the same cellular elements.

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