Ascorbic Acid - Instructions For Use, Indications, Doses, Analogues

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Vitamin C

Instructions for use:

1. 1. Release form and composition
2. 2. Indications for use
3. 3. Contraindications
4. 4. Method of application and dosage
5. 5. Side effects
6. 6. Special instructions
7. 7. Analogs
8. 8. Terms and conditions of storage

Prices in online pharmacies:

from 3 rubles.

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Ascorbic acid (vitamin C) is a drug belonging to the group of synthetic vitamins.

Release form and composition

Ascorbic acid is an active ingredient of vitamin products, the release form of which may be as follows:

• Dragee 0.05 g (50 and 200 pcs. In polymer cans);
• Lyophilisate for preparing a solution for intravenous and intramuscular administration, 0.05 g each (3 ml each in ampoules with a solvent, 5 ampoules in a cardboard box);
• Powder for preparation of oral solution (in sachets of 2.5 g);
• Solution for intravenous and intramuscular administration, in 1 ml - 0.05 g. Excipients: sodium sulfite anhydrous, sodium bicarbonate, water for injection (in 1 or 2 ml ampoules, 10 ampoules per package);
• Tablets of 25, 50, 75, 100 or 200 mg (10 pcs. In waxed paper, in non-cell contour packs; 50 pcs. (50 mg) in dark glass jars);
• Chewable tablets, 50 mg (10 pcs. In blisters, in a carton pack 5 blisters).

Indications for use

The use of Ascorbic acid is recommended in the case of hypo- and avitaminosis C (increased need for vitamin C) with: unbalanced diet, parenteral nutrition, intense mental and physical activity, convalescence after serious illness, scurvy, alcoholism, smoking, burn disease, prolonged hypothermia, prolonged fever, hyperthyroidism, chronic infections, diseases and surgical treatment of the gastrointestinal tract (persistent diarrhea, resection of the small intestine, peptic ulcer, gastrectomy), trauma, tuberculosis, pregnancy (especially multiple fetuses, as well as against the background of nicotine or drug dependence) and during lactation, artificial feeding and intensive growth, chronic intoxication with Fe preparations, idiopathic methemoglobinemia, prolonged stress,recovery in the postoperative period.

In laboratory practice, the drug is used in conjunction with sodium chromate 51Cr for labeling erythrocytes.

Contraindications

An absolute contraindication for the use of the drug in any dosage is hypersensitivity to ascorbic acid.

Long-term use in doses of more than 0.5 g is prohibited for the following diseases:

• Diabetes;
• Hyperoxaluria;
• Nephrourolithiasis;
• Deficiency of glucose-6-phosphate dehydrogenase;
• Thalassemia;
• Hemochromatosis.

Ascorbic acid in any dosage should be taken with caution (preferably under medical supervision) in case of glucose-6-phosphate dehydrogenase deficiency, hemochromatosis, diabetes mellitus, sideroblastic anemia, thalassemia, hyperoxaluria, and kidney stones.

Method of administration and dosage

Ascorbic acid is taken orally, as well as intramuscularly or intravenously in the following recommended doses:

• For adults: prophylactic - 0.05-0.1 g per day; therapeutic - from 0.05 to 0.1 g 3-5 times a day;
• For children: preventive - 0.025 g 3 times a day; therapeutic - 0.05-0.1 g 2-3 times a day;
• During pregnancy and lactation with a deficiency of vitamin C in the diet: 0.3 g per day, duration of use - about 2 weeks, then 0.1 g in order to prevent hypovitaminosis throughout the entire period of pregnancy and breastfeeding of the baby.

Intramuscularly or intravenously Ascorbic acid is prescribed in a dose of 1 to 3 ml of a 5% solution.

The course of treatment with preparations containing vitamin C depends on the nature of the disease and is prescribed by the attending physician.

Side effects

The use of Ascorbic acid can cause the following complications:

• Central nervous system: feeling of fatigue, dizziness (with rapid intravenous administration), headache, hyperexcitability, insomnia (with prolonged consumption of more than 1 g per day);
• Urinary system: moderate pollakiuria (at a dose of more than 600 mg / day), nephrolithiasis (from calcium oxalate), hyperoxaluria, damage to the renal glomerular apparatus (with prolonged use of large doses);
• Cardiovascular system: decreased capillary permeability with possible deterioration of tissue trophism, increased blood pressure, hypercoagulation, development of microangiopathies (with prolonged use in significant doses);
• Digestive system: irritation of the gastrointestinal mucosa (when ingested), damage to tooth enamel (with intensive use of chewable tablets or resorption of oral forms);
• Immune system: allergic manifestations (flushing of the skin, skin rash);
• Local reactions: possibly - painful sensations in the places of intramuscular injection of the solution;
• Others: suppression of the function of the insular apparatus of the pancreas (hyperglycemia, glucosuria), increased hemolysis of erythrocytes (with prolonged use of more than 1 g of Ascorbic acid per day), termination of pregnancy as a result of hyperestrogenemia (with intravenous administration of significant doses of the drug).

The consequence of taking this vitamin preparation may be such laboratory parameters as: thrombocytosis, hypoprothrombinemia, hypokalemia, glucosuria, neutrophilic leukocytosis, erythropenia.

In all cases of side effects, symptomatic therapy and forced diuresis are recommended.

special instructions

During treatment, it is necessary to control blood pressure and adrenal function, since vitamin C stimulates the synthesis of corticosteroid hormones.

With an increased content of iron (Fe) in the body, it is allowed to take ascorbic acid only in minimal doses.

It should be borne in mind that taking vitamin C can cause distortion of laboratory test results, such as blood sugar and urine, lactate dehydrogenase and transaminase activity, and bilirubin in liver tests.

Vitamin C should not be taken without a doctor's prescription, especially for women during pregnancy and lactation.

Analogs

Preparations in which the main active ingredient is ascorbic acid: Additive Vitamin C, Asvitol Ascovit, Vitamin C Rostvit, Setebe 500, Tsevikap, Celaskon, Citravit, etc.

A drug that is similar in its mechanism of action and belongs to one pharmaceutical subgroup: Upsavit vitamin C chewable tablets.

Terms and conditions of storage

Storage conditions and periods are different for each form of Ascorbic Acid release and are indicated on the packages.

Ascorbic acid: prices in online pharmacies

Drug name Price Pharmacy

Ascorbic acid Meligen powder for preparation of oral solution 2.5 g 1 pc. RUB 3 Buy

Ascorbic acid with glucose 100 mg + 877 mg tablets 10 pcs. RUB 4 Buy

Ascorbic acid Eco powder for solution for oral administration 2.5 g 1 pc. RUB 4 Buy

Ascorbic acid 25 mg tablets 10 pcs. RUB 5 Buy

Ascorbic acid with glucose 100 mg chewable tablets 10 pcs. RUB 5 Buy

Ascorbic acid with glucose 100 mg + 877 mg tablets 10 pcs. RUB 6 Buy

Ascorbic acid with glucose Meligen 1 g tablets 10 pcs. RUB 7 Buy

Ascorbic acid 50 mg tablets 10 pcs. RUB 8 Buy

Ascorbic acid 75 mg tablets 10 pcs. RUB 8 Buy

Ascorbic acid with glucose 100 mg + 877 mg tablets 10 pcs. RUB 8 Buy

Ascorbic acid with Sesana sugar 2.9 g chewable tablets with strawberry flavor 10 pcs. RUB 9 Buy

Ascorbic acid chewable tablets 75mg 10 pcs RUB 10 Buy

Ascorbic acid 2.5 g powder for solution for oral administration 50 pcs. RUB 11 Buy

Ascorbic acid with sugar Kvadrat-S 2.9 g strawberry tablets 10 pcs. RUB 11 Buy

Ascorbic acid chewable tablets 50mg 10 pcs RUB 12 Buy

Ascorbic acid with sugar Kvadrat-S 2.9 g cherry tablets 10 pcs. RUB 12 Buy

Ascorbic acid with sugar Kvadrat-S 2.9 g tablets with lemon flavor 10 pcs. RUB 15 Buy

Ascorbic acid 50 mg pills 200 pcs. RUB 18 Buy

Ascorbic acid 50 mg pills 200 pcs. RUB 19 Buy

Ascorbic acid with glucose 100 mg + 877 mg tablets 40 pcs. 22 RUB Buy

Ascorbic acid (for injection) 50 mg / ml solution for intravenous and intramuscular administration 2 ml 10 pcs. RUB 23 Buy

Ascorbic acid (for injection) 50 mg / ml solution for intravenous and intramuscular administration 1 ml 10 pcs. RUB 25 Buy

Ascorbic acid (BAA) dragee 200 pcs. RUB 25 Buy

Ascorbic acid 50 mg pills 200 pcs. RUB 27 Buy

Ascorbic acid (for injection) 50 mg / ml solution for intravenous and intramuscular administration 2 ml 10 pcs. RUB 30 Buy

Ascorbic acid with glucose 100 mg + 877 mg tablets 20 pcs. RUB 30 Buy

Ascorbic acid (for injection) 50 mg / ml solution for intravenous and intramuscular administration 2 ml 10 pcs. RUB 31 Buy

ZdravCity Ascorbic Acid 25 Strawberry Flavored 770 mg Tablets 10 pcs 32 RUB Buy

ZdravCity Ascorbic Acid 25 Orange Flavored 770 mg Tablets 10 pcs 32 RUB Buy

Zdravcity Ascorbic acid 25 25 mg strawberry flavored tablets 10 pcs. 32 RUB Buy

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Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!