Coldact Flu Plus
Coldakt Flu Plus: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. In case of impaired renal function
- 12. For violations of liver function
- 13. Drug interactions
- 14. Analogs
- 15. Terms and conditions of storage
- 16. Terms of dispensing from pharmacies
- 17. Reviews
- 18. Price in pharmacies
Latin name: Coldact Flu Plus
ATX code: N02BE51
Active ingredient: Paracetamol + Phenylephrine + Chlorphenamine (Paracetamol + Phenylephrine + Chlorphenamine)
Producer: Natco Pharma (India)
Description and photo update: 2018-22-10
Prices in pharmacies: from 146 rubles.
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Coldakt Flu Plus is a combined preparation with antipyretic, antihistamine, analgesic, anti-congestive and alpha-adrenomimetic action. It is used for the symptomatic treatment of colds and acute respiratory diseases (ARI).
Release form and composition
- extended-release capsules: size no. 0, hard, gelatinous, with a transparent body and a red cap; contents - pellets of almost white or white, yellow and from orange to red color (10 pcs. in blisters, in a cardboard box of 1 or 10 blisters);
- suspension for oral administration: orange in color with a characteristic odor (in dark glass bottles of 60 ml, in a cardboard box 1 bottle complete with a dosing spoon).
Capsules
Active ingredients in 1 capsule:
- paracetamol - 200 mg;
- phenylephrine hydrochloride - 25 mg;
- chlorphenamine maleate - 8 mg.
Additional components:
- excipients: Non Pareil Seeds 18/22 granules (sugar crumbs: starch syrup, sucrose), diethyl phthalate, microcrystalline cellulose, ethyl cellulose, hypromellose, disodium edetate, sodium disulfite, povidone, talc, isopropanol (lost during production), purified water is lost during the production process), dyes sunset yellow, quinoline yellow and crimson (Ponso 4 R);
- shell composition: methyl parahydroxybenzoate, gelatin, propyl parahydroxybenzoate, purified water, crimson dyes (Ponso 4R) and azorubin.
Oral suspension
Active substances in a 5 ml suspension:
- paracetamol - 125 mg;
- phenylephrine hydrochloride - 5 mg;
- chlorphenamine maleate - 2 mg.
Additional components: propyl parahydroxybenzoate, sodium citrate, colloidal silicon dioxide, disodium edetate, citric acid, microcrystalline cellulose, sodium saccharinate, xanthan gum, sodium carmellose, sodium chloride, polysorbate 20, sucrose, glycerin, methyl parahydroxybenzoate, 50 aromatized water, orange (051941CS2) and pineapple (503092C), sunset yellow dye.
Pharmacological properties
Coldakt Flu Plus is a long-acting drug with a combined composition.
Paracetamol has an analgesic and antipyretic effect: it reduces high body temperature, reduces the pain syndrome characteristic of colds - sore throat, joint, muscle and headache.
Phenylephrine has a vasoconstrictor property: it reduces hyperemia and edema of the mucous membranes of the paranasal sinuses and upper respiratory tract.
Chlorphenamine has an anti-allergic effect: it eliminates itching in the nose and eyes, as well as watery eyes.
Indications for use
Coldakt Flu Plus is used for the symptomatic treatment of influenza, colds and acute respiratory viral infections (to eliminate rhinorrhea, febrile and pain syndromes).
Contraindications
- thyrotoxicosis;
- diabetes;
- diseases of the pancreas;
- peptic ulcer of the stomach and duodenum;
- severe diseases of the heart, kidneys, liver, bladder;
- adenoma of the prostate gland, accompanied by difficulty urinating;
- diseases of the blood system;
- deficiency of the enzyme glucose-6-phosphate dehydrogenase;
- angle-closure glaucoma;
- arterial hypertension;
- severe atherosclerosis of the coronary arteries;
- pregnancy;
- lactation period;
- children age: up to 12 years - for capsules, up to 6 years - for suspension;
- hypersensitivity to any component of the drug.
According to the instructions, Coldakt Flu Plus should be used with caution in chronic obstructive pulmonary disease, bronchial asthma, congenital hyperbilirubinemia (Gilbert, Rotor and Dubin-Johnson syndromes).
Instructions for the use of Coldact Flu Plus: method and dosage
Coldact Flu Plus should be taken orally. The suspension bottle must be shaken before each dose.
Capsules for adults and adolescents from 12 years old are prescribed 1 pc. 2 times a day (at 12-hour intervals) with a course of 3-5 days.
Single doses of the drug in the form of a suspension:
- for adults and adolescents from 12 years old - 10 ml (2 teaspoons);
- for children 6–12 years old - 5 ml (1 teaspoon).
The frequency of admission is 3-4 times a day.
You can take Coldakt Flu Plus no more than 3 days as an antipyretic agent, no more than 5 days as an analgesic.
Side effects
During the period of therapy with Coldact Flu Plus, the following side effects may develop: sleep disturbance, drowsiness, increased excitability, dizziness, increased blood pressure, tachycardia, increased intraocular pressure, paresis of accommodation, mydriasis, dry mucous membranes, impaired appetite, pain in the epigastric region, nausea; rarely - leukopenia, thrombocytopenia, agranulocytosis, anemia; very rarely - allergic reactions (urticaria, itching, skin rash, angioedema), urinary retention.
With prolonged use of the drug in high doses, the development of nephrotoxic and hepatotoxic effects is possible.
Overdose
In case of a significant excess of the recommended dose (more than 10,000-15,000 mg of paracetamol), an overdose may develop, manifested by pallor of the skin, decreased appetite, nausea, vomiting, increased activity of hepatic transaminases, hepatonecrosis, and increased prothrombin time.
If no more than 6 hours have passed after administration, gastric lavage should be performed. Within 8-9 hours after an overdose, donors of SH-groups and precursors of glutathione synthesis (methionine) are administered, within 12 hours N-acetylcysteine is administered.
If you accidentally take a dose that significantly exceeds the recommended one, you must immediately consult a doctor, even if there are no negative symptoms.
special instructions
Coldakt Flu Plus may affect the results of laboratory tests (the quantitative determination of glucose and uric acid in plasma).
With long-term treatment, it is necessary to monitor the functional state of the liver and the parameters of peripheral blood.
During the period of treatment, it is necessary to refrain from drinking alcoholic beverages.
Simultaneously with Coldact Flu Plus, you should not take other drugs containing paracetamol, as well as sleeping pills, tranquilizers or other psychotropic drugs.
Without a doctor's prescription, the drug is forbidden to be taken by patients undergoing therapy with monoamine oxidase inhibitors.
If during treatment the fever persists or the body temperature rises again, a doctor's consultation is required.
Influence on the ability to drive vehicles and complex mechanisms
Due to the risk of drowsiness and (or) dizziness during the period of therapy, it is recommended to refrain from driving vehicles and performing work that requires quick reactions and increased attention.
Application during pregnancy and lactation
The use of the drug is contraindicated during pregnancy and lactation.
Pediatric use
In the form of capsules, Coldakt Flu Plus is not prescribed for children under 12 years old, in the form of a suspension - up to 6 years.
With impaired renal function
The use of the drug is contraindicated in severe kidney disease.
For violations of liver function
The use of the drug is contraindicated in severe liver diseases.
Drug interactions
Coldakt Flu Plus reduces the severity of the hypotensive effect of guanethidine, and also enhances the effects of monoamine oxidase inhibitors, ethanol and sedatives.
Paracetamol, which is part of the composition, reduces the effect of uricosuric drugs.
Tricyclic antidepressants and guanethidine enhance the alpha-adrenostimulating activity of phenylephrine.
With the simultaneous use of the following drugs with Coldact Flu Plus, undesirable effects may develop:
- halothane: ventricular arrhythmia;
- phenothiazine derivatives, antidepressants, antipsychotic and antiparkinsonian drugs: dry mouth, urinary retention, constipation;
- glucocorticosteroids: glaucoma;
- furazolidone: agitation, hypertensive crisis, hyperpyrexia;
- rifampicin, carbamazepine, diphenin, barbiturates, zidovudine and other inducers of liver microsomal enzymes: increased hepatotoxic effect of paracetamol.
Analogs
AntiFlu, Theraflu, TeraFlu ExtraTab, Rinza, Fervex, Pharmacitron, Coldrex, Coldfree, Cameflu, Gripcold, Effect Flu, etc. are analogs of Coldact Flu Plus.
Terms and conditions of storage
Store in a dry (capsule) place out of reach of children with an ambient temperature of up to 25 ° C. Avoid freezing the suspension.
Shelf life is 2 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Coldact Flu Plus
According to reviews, Coldakt Flu Plus is an effective drug that significantly alleviates the symptoms of colds and flu, in particular, quickly reduces fever, eliminates nasal congestion, watery eyes and rhinorrhea. The main thing is to start taking it as early as possible after the onset of symptoms of the disease, then, in the opinion of many, recovery occurs within 3-5 days.
To an additional advantage of the drug in the form of capsules, patients attribute a long-term effect - up to 12 hours, due to which it is necessary to take the drug only 2 times a day, which is especially important for the night period.
In addition, Coldakt Flu Plus, judging by the reviews, practically does not cause side effects. Rare adverse events include increased drowsiness.
Price for Coldact Flu Plus in pharmacies
The price of Coldact Flu Plus is:
- 140–250 rubles for a pack of 10 capsules;
- an average of 100 rubles for 1 bottle of suspension.
Coldakt Flu Plus: prices in online pharmacies
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Drug name Price Pharmacy |
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Coldakt Flu Plus capsules of prolonged action 10 pcs. 146 r Buy |
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Coldakt Flu Plus prolonged action capsules 10 pcs. 178 r Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
